Patents by Inventor Zhaohui Zhou

Zhaohui Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240095563
    Abstract: The present disclosure provides a quantum convolution operator, comprising: a quantum state encoding module, a quantum entanglement module, a quantum convolution kernel module, a measuring module, and a computing module; the quantum state encoding module is configured to encode a current group of input data onto qubits; the quantum entanglement module is configured to associate quantum state information of different qubits; the quantum convolution kernel module is configured to extract feature information corresponding to the quantum state information; the measuring module is configured to measure a quantum state of a preset qubit and obtain a corresponding amplitude; the computing module is configured to compute a convolution result corresponding to the current group of input data according to the measured quantum state and its amplitude.
    Type: Application
    Filed: February 23, 2022
    Publication date: March 21, 2024
    Applicant: ORIGIN QUANTUM COMPUTING TECHNOLOGY (HEFEI) CO., LTD.
    Inventors: Menghan Dou, Yuan Fang, Zhaohui Zhou, Hanchao Wang, Lei Li
  • Patent number: 11891663
    Abstract: The present invention is directed to methods, reagents, kits, and compositions for identifying and quantifying target polynucleotide sequences. A linker probe comprising a 3? target specific portion, a loop, and a stem is hybridized to a target polynucleotide and extended to form a reaction product that includes a reverse primer portion and the stem nucleotides. A detector probe, a specific forward primer, and a reverse primer can be employed in an amplification reaction wherein the detector probe can detect the amplified target polynucleotide based on the stem nucleotides introduced by the linker probe. In some embodiments a plurality of short miRNAs are queried with a plurality of linker probes, wherein the linker probes all comprise a universal reverse primer portion a different 3? target specific portion and different stems. The plurality of queried miRNAs can then be decoded in a plurality of amplification reactions.
    Type: Grant
    Filed: August 26, 2020
    Date of Patent: February 6, 2024
    Assignee: APPLIED BIOSYSTEMS, LLC
    Inventors: Caifu Chen, Dana Ridzon, Zhaohui Zhou, Kai Qin Lao, Neil A. Straus
  • Publication number: 20230193223
    Abstract: Provided herein are compositions and systems for use in polymerase-dependent, nucleotide transient-binding methods. The methods are useful for deducing the sequence of a template nucleic acid molecule and single nucleotide polymorphism (SNP) analyses. The methods rely on the fact that the polymerase transient-binding time for a complementary nucleotide is longer compared to that of a non-complementary nucleotide. The labeled nucleotides transiently-binds the polymerase in a template-dependent manner, but does not incorporate. The methods are conducted under any reaction condition that permits transient binding of a complementary or non-complementary nucleotide to a polymerase, and inhibits nucleotide incorporation.
    Type: Application
    Filed: September 16, 2022
    Publication date: June 22, 2023
    Inventors: Peter VANDER HORN, Cheng-Yao CHEN, Guobin LUO, Michael PREVITE, Jamshid TEMIROV, Theo NIKIFOROV, Zhaohui ZHOU, Hongye SUN, Yufang WANG, Stefanie Yukiko NISHIMURA, Hongyi WANG, Marian PERIS, Barnett ROSENBLUM, Michael PHELAN
  • Patent number: 11447756
    Abstract: Provided herein are compositions and systems for use in polymerase-dependent, nucleotide transient-binding methods. The methods are useful for deducing the sequence of a template nucleic acid molecule and single nucleotide polymorphism (SNP) analyses. The methods rely on the fact that the polymerase transient-binding time for a complementary nucleotide is longer compared to that of a non-complementary nucleotide. The labeled nucleotides transiently-binds the polymerase in a template-dependent manner, but does not incorporate. The methods are conducted under any reaction condition that permits transient binding of a complementary or non-complementary nucleotide to a polymerase, and inhibits nucleotide incorporation.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: September 20, 2022
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Peter Vander Horn, Cheng-Yao Chen, Guobin Luo, Michael Previte, Jamshid Temirov, Theo Nikiforov, Zhaohui Zhou, Hongye Sun, Yufang Wang, Stefanie Yukiko Nishimura, Hongyi Wang, Marian Peris, Barnett Rosenblum, Michael Phelan
  • Patent number: 11359758
    Abstract: In a sectional-type high wear-resistant double-layer straight tube and a method for preparing the same, the double-layer straight tube includes a protective outer tube and a sectional-type wear-resistant inner tube. The protective outer tube is nested outside of the sectional-type wear-resistant inner tube; the sectional-type wear-resistant inner tube includes at least two wear-resistant inner tube sections; and the wear-resistant inner tube sections are connected sequentially. The sectional-type wear-resistant inner tube at least includes a left inner tube section, a right inner tube section, and one or more middle inner tube section. The wear-resistant straight tube can greatly prolong the service life of the pipeline so that the cost performance of the pipeline is increased by more than a few times. It would also easily achieve mass production, the quality is stable and reliable, and the safety performance is high.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: June 14, 2022
    Inventor: Zhaohui Zhou
  • Publication number: 20210108755
    Abstract: In a sectional-type high wear-resistant double-layer straight tube and a method for preparing the same, the double-layer straight tube includes a protective outer tube and a sectional-type wear-resistant inner tube. The protective outer tube is nested outside of the sectional-type wear-resistant inner tube; the sectional-type wear-resistant inner tube includes at least two wear-resistant inner tube sections; and the wear-resistant inner tube sections are connected sequentially. The sectional-type wear-resistant inner tube at least includes a left inner tube section, a right inner tube section, and one or more middle inner tube section. The wear-resistant straight tube can greatly prolong the service life of the pipeline so that the cost performance of the pipeline is increased by more than a few times. It would also easily achieve mass production, the quality is stable and reliable, and the safety performance is high.
    Type: Application
    Filed: April 12, 2018
    Publication date: April 15, 2021
    Inventor: Zhaohui ZHOU
  • Publication number: 20200407789
    Abstract: The present invention is directed to methods, reagents, kits, and compositions for identifying and quantifying target polynucleotide sequences. A linker probe comprising a 3? target specific portion, a loop, and a stem is hybridized to a target polynucleotide and extended to form a reaction product that includes a reverse primer portion and the stem nucleotides. A detector probe, a specific forward primer, and a reverse primer can be employed in an amplification reaction wherein the detector probe can detect the amplified target polynucleotide based on the stem nucleotides introduced by the linker probe. In some embodiments a plurality of short miRNAs are queried with a plurality of linker probes, wherein the linker probes all comprise a universal reverse primer portion a different 3? target specific portion and different stems. The plurality of queried miRNAs can then be decoded in a plurality of amplification reactions.
    Type: Application
    Filed: August 26, 2020
    Publication date: December 31, 2020
    Inventors: Caifu CHEN, Dana RIDZON, Zhaohui ZHOU, Kai Qin LAO, Neil A. STRAUS
  • Patent number: 10781486
    Abstract: The present invention is directed to methods, reagents, kits, and compositions for identifying and quantifying target polynucleotide sequences. A linker probe comprising a 3? target specific portion, a loop, and a stem is hybridized to a target polynucleotide and extended to form a reaction product that includes a reverse primer portion and the stem nucleotides. A detector probe, a specific forward primer, and a reverse primer can be employed in an amplification reaction wherein the detector probe can detect the amplified target polynucleotide based on the stem nucleotides introduced by the linker probe. In some embodiments a plurality of short miRNAs are queried with a plurality of linker probes, wherein the linker probes all comprise a universal reverse primer portion a different 3? target specific portion and different stems. The plurality of queried miRNAs can then be decoded in a plurality of amplification reactions.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: September 22, 2020
    Assignee: Applied Biosystems, LLC
    Inventors: Caifu Chen, Dana Ridzon, Zhaohui Zhou, Kai Qin Lao, Neil A. Straus
  • Publication number: 20200231948
    Abstract: Provided herein are compositions and systems for use in polymerase-dependent, nucleotide transient-binding methods. The methods are useful for deducing the sequence of a template nucleic acid molecule and single nucleotide polymorphism (SNP) analyses. The methods rely on the fact that the polymerase transient-binding time for a complementary nucleotide is longer compared to that of a non-complementary nucleotide. The labeled nucleotides transiently-binds the polymerase in a template-dependent manner, but does not incorporate. The methods are conducted under any reaction condition that permits transient binding of a complementary or non-complementary nucleotide to a polymerase, and inhibits nucleotide incorporation.
    Type: Application
    Filed: March 20, 2020
    Publication date: July 23, 2020
    Inventors: Peter VANDER HORN, Cheng-Yao CHEN, Guobin LUO, Michael PREVITE, Jamshid TEMIROV, Theo NIKIFOROV, Zhaohui ZHOU, Hongye SUN, Yufang WANG, Stefanie Yukiko NISHIMURA, Hongyi WANG, Marian PERIS, Barnett ROSENBLUM, Michael PHELAN
  • Patent number: 10597642
    Abstract: Provided herein are compositions and systems for use in polymerase-dependent, nucleotide transient-binding methods. The methods are useful for deducing the sequence of a template nucleic acid molecule and single nucleotide polymorphism (SNP) analyses. The methods rely on the fact that the polymerase transient-binding time for a complementary nucleotide is longer compared to that of a non-complementary nucleotide. The labeled nucleotides transiently-binds the polymerase in a template-dependent manner, but does not incorporate. The methods are conducted under any reaction condition that permits transient binding of a complementary or non-complementary nucleotide to a polymerase, and inhibits nucleotide incorporation.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: March 24, 2020
    Assignee: Life Technologies Corporation
    Inventors: Peter Vander Horn, Cheng-Yao Chen, Guobin Luo, Michael Previte, Jamshid Temirov, Theo Nikiforov, Zhaohui Zhou, Hongye Sun, Yufang Wang, Stefanie Yukiko Nishimura, Hongyi Wang, Marian Peris, Barnett Rosenblum, Michael Phelan
  • Patent number: 10428994
    Abstract: An auto-fill two-layer two-half wear resistant elbow of a concrete pump truck consists of an outer-layer protection elbow, an inner-layer heterogeneous wear resistant combined elbow and a wear resistant connecting flange. A filling space is provided between the outer-layer protection elbow and the inner-layer heterogeneous wear resistant combined elbow. The wear resistant elbow is designed as a two-layer two-half unique structure including a protection layer and a wear resistant layer. Upon using the wear resistant elbow for the first time, the concrete grout fills the reserved slit via the heterogenous combined elbow and enters the reserved filling space, allowing the outer-layer protection elbow and the inner-layer heterogeneous wear resistant combined elbow to be fixed as a whole.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: October 1, 2019
    Inventor: Zhaohui Zhou
  • Publication number: 20190061164
    Abstract: An interactive robot includes an input module having at least one input element, an output module having at least one output element, a communication unit in communication with a server, a storage unit, and at least one processor. The processor establishes at least one of the at least one input elements as a standby input element and establishes at least one of the at least one output element as a standby output element, obtains input information from the at least one standby input element, analyzes the input information and generates a control command according to the input information, and executes the control command through the at least one standby output element.
    Type: Application
    Filed: November 17, 2017
    Publication date: February 28, 2019
    Inventors: Zhaohui Zhou, Neng-De Xiang, Xue-Qin Zhang
  • Publication number: 20190004567
    Abstract: A display device includes a shell, a displaying module, and a touch plate. The shell defines a receiving space and includes a frame and two connecting strips horizontally extending from two fixed sides of the frame. The displaying module is received in the receiving space. The touch plate is received in the receiving space and includes a touch sensor member and a touch glass member. A touch glass layer is overlapped on the touch sensor layer. Two ends of the touch glass layer extend out of the touch sensor layer and are attached to an upper surface of the two connecting strips. The disclosure further provides a method for assembling the display device.
    Type: Application
    Filed: August 29, 2017
    Publication date: January 3, 2019
    Inventors: ZHAOHUI ZHOU, PING-HAO LIU, FA-MING WU, XUE-QIN ZHANG
  • Publication number: 20180370041
    Abstract: A smart robot with enhanced communication capabilities includes a camera, a voice collection unit configured to collect verbal commands, and a processor coupled with the camera and the voice collection unit. The smart robot receives user's voice through the voice collection unit, identifies and verifies the user's face image captured by the camera, recognizes voice of such verified user and verbal instructions therefrom, and determines and executes a behavior instruction according to multiple relationship tables, to interact with such user or to cause other objects to function according to the user's command.
    Type: Application
    Filed: April 9, 2018
    Publication date: December 27, 2018
    Inventors: CHIH-SIUNG CHIANG, ZHAOHUI ZHOU, NENG-DE XIANG, XUE-QIN ZHANG, CHIEH CHUNG
  • Publication number: 20180259113
    Abstract: A two-branch or multi-branch double-layer wear-and-impact-resistant tube and manufacturing method thereof. The wear-and-impact-resistant tube comprises an outer protective tube and an inner wear-resistant assembled tube nested in the outer protective tube. The inner wear-resistant assembled tube comprises two or more tube walls, the two or more tube walls are jointed to form a tube having an annular cross section. The wear-and-impact-resistant tube can be a straight tube or a bent tube. If the wear-and-impact-resistant tube is a straight tube, upper and lower portions of the inner wear-resistant assembled tube employ different structures, and if the wear-and-impact-resistant tube is a bent tube, a large curved portion and a small curved portion of the bent tube employ different structures. The inner assembled tube of the wear-and-impact-resistant tube is divided into at least two portions, and the at least two portions thereof employ different structures.
    Type: Application
    Filed: March 10, 2016
    Publication date: September 13, 2018
    Inventor: Zhaohui ZHOU
  • Publication number: 20180130557
    Abstract: A method for reading and recording physical condition of a user using an electronic device includes reading and recording physiological status of user when at least one collecting device of the electronic device is collecting physiological readings of a user. The readings are received by the electronic device, and a geographic location of the electronic device and environmental information of the geographic location are also acquired. A report and warning if necessary about physical condition of the user is generated by analyzing the status recorded and the environment information.
    Type: Application
    Filed: September 29, 2017
    Publication date: May 10, 2018
    Inventors: CHIH-SIUNG CHIANG, ZHAOHUI ZHOU, NENG-DE XIANG, PING-HAO LIU, XUE-QIN ZHANG
  • Publication number: 20170369857
    Abstract: Provided herein are compositions and systems for use in polymerase-dependent, nucleotide transient-binding methods. The methods are useful for deducing the sequence of a template nucleic acid molecule and single nucleotide polymorphism (SNP) analyses. The methods rely on the fact that the polymerase transient-binding time for a complementary nucleotide is longer compared to that of a non-complementary nucleotide. The labeled nucleotides transiently-binds the polymerase in a template-dependent manner, but does not incorporate. The methods are conducted under any reaction condition that permits transient binding of a complementary or non-complementary nucleotide to a polymerase, and inhibits nucleotide incorporation.
    Type: Application
    Filed: August 30, 2017
    Publication date: December 28, 2017
    Inventors: Peter VANDER HORN, Cheng-Yao CHEN, Guobin LUO, Michael PREVITE, Jamshid TEMIROV, Theo NIKIFOROV, Zhaohui ZHOU, Hongye SUN, Yufang WANG, Stefanie Yukiko NISHIMURA, Hongyi WANG, Marian PERIS, Barnett ROSENBLUM, Michael PHELAN
  • Publication number: 20170314724
    Abstract: An auto-fill two-layer two-half wear resistant elbow of a concrete pump truck consists of an outer-layer protection elbow, an inner-layer heterogeneous wear resistant combined elbow and a wear resistant connecting flange. A filling space is provided between the outer-layer protection elbow and the inner-layer heterogeneous wear resistant combined elbow. The wear resistant elbow is designed as a two-layer two-half unique structure including a protection layer and a wear resistant layer, wherein the protection layer protects the wear resistant layer from distortion or even damage by external force and distortion or even damage by impact force by internal materials during the transportation, installation and use of the elbow.
    Type: Application
    Filed: January 28, 2016
    Publication date: November 2, 2017
    Inventor: Zhaohui ZHOU
  • Publication number: 20170292158
    Abstract: The present invention is directed to methods, reagents, kits, and compositions for identifying and quantifying target polynucleotide sequences. A linker probe comprising a 3? target specific portion, a loop, and a stem is hybridized to a target polynucleotide and extended to form a reaction product that includes a reverse primer portion and the stem nucleotides. A detector probe, a specific forward primer, and a reverse primer can be employed in an amplification reaction wherein the detector probe can detect the amplified target polynucleotide based on the stem nucleotides introduced by the linker probe. In some embodiments a plurality of short miRNAs are queried with a plurality of linker probes, wherein the linker probes all comprise a universal reverse primer portion a different 3? target specific portion and different stems. The plurality of queried miRNAs can then be decoded in a plurality of amplification reactions.
    Type: Application
    Filed: April 18, 2017
    Publication date: October 12, 2017
    Inventors: Caifu CHEN, Dana RIDZON, Zhaohui ZHOU, Kai Qin LAO, Neil A. STRAUS
  • Patent number: 9765310
    Abstract: Provided herein are compositions and systems for use in polymerase-dependent, nucleotide transient-binding methods. The methods are useful for deducing the sequence of a template nucleic acid molecule and single nucleotide polymorphism (SNP) analyses. The methods rely on the fact that the polymerase transient-binding time for a complementary nucleotide is longer compared to that of a non-complementary nucleotide. The labeled nucleotides transiently-binds the polymerase in a template-dependent manner, but does not incorporate. The methods are conducted under any reaction condition that permits transient binding of a complementary or non-complementary nucleotide to a polymerase, and inhibits nucleotide incorporation.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: September 19, 2017
    Assignee: Life Technologies Corporation
    Inventors: Peter Vander Horn, Cheng-Yao Chen, Guobin Luo, Michael Previte, Jamshid Temirov, Theo Nikiforov, Zhaohui Zhou, Hongye Sun, Yufang Wang, Stefanie Yukiko Nishimura, Hongyi Wang, Marian Peris, Barnett Rosenblum, Michael Phelan