Patents by Inventor Zhaoji WANG

Zhaoji WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250025608
    Abstract: The present invention belongs to the technical field of mechanical manufacturing and medical device surface processing, and specifically discloses a metal with a microporous surface structure, a preparation method therefor, and an application thereof. According to the present invention, a metal is sequentially sanded and polished, and then subjected to ultrasonic cavitation, wherein conditions for the ultrasonic cavitation are as follows: the ultrasonic cavitation is performed for 1-240 min, an amplitude of ultrasonic equipment is 1-100 ?m, an output power of the ultrasonic equipment is 5-200 W, and an ultrasonic frequency is 15000-55000 Hz; and the metal with a microporous surface structure is obtained. The method disclosed by the present invention has the advantages of low cost, simple operation, and no pollution to the surface, can solve the preparation of micropores on small and micro surfaces, and has potential wide application prospects in medical biology and other related fields.
    Type: Application
    Filed: April 4, 2023
    Publication date: January 23, 2025
    Applicant: YANSHAN UNIVERSITY
    Inventors: Hongwang ZHANG, Xin WANG, Zhaoji WANG
  • Patent number: 11813334
    Abstract: The present invention relates to the technical field of medicines, and relates to a polyethylene glycol conjugated drug, a preparation method therefor and the use thereof. In particular, the present invention relates to a polyethylene glycol conjugated drug as shown in formula I or a pharmaceutically acceptable salt thereof. The present invention also relates to a method for preparing the polyethylene glycol conjugated drug or the pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the polyethylene glycol conjugated drug or the pharmaceutically acceptable salt thereof, and the use thereof in the preparation of a drug.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: November 14, 2023
    Assignee: CHONGQING UPGRA BIOTECHNOLOGY CO., LTD.
    Inventors: Gaoquan Li, Dajun Li, Qian Zhang, Diedie Li, Chengzhi Gao, Yue Liu, Xiaoling Ding, Yusong Wei, Xiangwei Yang, Yongchen Peng, Jia Gao, Qiang Luo, Yanxia Heng, Mei Liu, Yuyang Yi, Xiafan Zeng, Tao Tu, Xiao Tang, Xi Liu, Jianhuan Li, Zhaojie Wang, Bin Wang, Jinping Wan, Mingyang Hou, Jiao Liu, Huiyu Chen, Jie Lou, Yue Yang, Yuanqiang Wang
  • Publication number: 20230101564
    Abstract: The present invention relates to the technical field of medicines, and relates to a polyethylene glycol conjugated drug, a preparation method therefor and the use thereof. In particular, the present invention relates to a polyethylene glycol conjugated drug as shown in formula I or a pharmaceutically acceptable salt thereof. The present invention also relates to a method for preparing the polyethylene glycol conjugated drug or the pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the polyethylene glycol conjugated drug or the pharmaceutically acceptable salt thereof, and the use thereof in the preparation of a drug.
    Type: Application
    Filed: March 11, 2020
    Publication date: March 30, 2023
    Inventors: Gaoquan LI, Dajun LI, Qian ZHANG, Diedie LI, Chengzhi GAO, Yue LIU, Xiaoling DING, Yusong WEI, Xiangwei YANG, Yongchen PENG, Jia GAO, Qiang LUO, Yanxia HENG, Mei LIU, Yuyang YI, Xiafan ZENG, Tao TU, Xiao TANG, Xi LIU, Jianhuan LI, Zhaojie WANG, Bin WANG, Jinping WAN, Mingyang HOU, Jiao LIU, Huiyu CHEN, Jie LOU, Yue YANG, Yuanqiang WANG
  • Publication number: 20230073036
    Abstract: The disclosure relates to the technical field of medicine, specifically to a polyethylene glycol conjugated drug, a preparation method therefor and use thereof, and relates in particular to a polyethylene glycol conjugated drug represented by formula (I) or a pharmaceutically acceptable salt thereof. The disclosure further relates to a method for preparation of the polyethylene glycol conjugated drug or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the polyethylene glycol conjugated drug or a pharmaceutically acceptable salt thereof, and use of the polyethylene glycol conjugated drug or a pharmaceutically acceptable salt thereof in preparation of a medicament.
    Type: Application
    Filed: March 11, 2020
    Publication date: March 9, 2023
    Inventors: Gaoquan LI, Qian ZHANG, Dajun LI, Diedie LI, Chengzhi GAO, Xiaoling DING, Yue LIU, Yusong WEI, Xiangwei YANG, Yongchen PENG, Jia GAO, Qiang LUO, Yanxia HENG, Mei LIU, Yuyang YI, Xiafan ZENG, Tao TU, Xiao TANG, Xi LIU, Jianhuan LI, Zhaojie WANG, Jinping WAN, Mingyang HOU, Jie LOU, Huiyu CHEN, Yue YANG, Yuanqiang WANG
  • Publication number: 20230016403
    Abstract: The present disclosure provides a method of processing triple data, a method of training a triple data processing model, an electronic device, and a storage medium. A specific implementation solution includes: performing a triple data extraction on text data to obtain a plurality of field data; normalizing the plurality of field data to determine target triple data, wherein the target triple data contains entity data, entity relationship data, and association entity data; and verifying a confidence level of the target triple data to obtain a verification result.
    Type: Application
    Filed: September 23, 2022
    Publication date: January 19, 2023
    Inventors: Zhaoji WANG, Fang HUANG, Ye JIANG, Yabing SHI, Chunguang CHAI, Yong ZHU