Patents by Inventor Zhaoqing Ding

Zhaoqing Ding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Influenza virus vaccines and uses thereof
    Patent number: 10517941
    Abstract: Provided are influenza hemagglutinin stem domain polypeptides comprising (a) an influenza hemagglutinin HA1 domain that comprises an HA1 N-terminal stem segment comprising the amino acids from position 1 to position x, preferably from position p to position x, of the HA1 domain, covalently linked by a linking sequence of 0-50 amino acid residues to an HA1 C-terminal stem segment, comprising the amino acids from position y to and including the C-terminal amino acid of the HA1 domain; and (b) an influenza hemagglutinin HA2 domain, wherein the hemagglutinin stem domain polypeptide is resistant to protease cleavage at the junction between HA1 and HA2, and wherein one or more amino acid of the amino acids at positions 337, 340, 352, 353, 402, 406, 409, 413 and/or 416 have been mutated, as compared to the corresponding positions in wild-type influenza HA.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: December 31, 2019
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Jan Willem Meijberg, Antonietta Impagliazzo, Katarina Radosevic, Jehangir Wadia, Robert Anthony Williamson, Michelle Wagner, Zhaoqing Ding
  • Influenza virus vaccines and uses thereof
    Patent number: 10328144
    Abstract: Provided herein are influenza hemagglutinin stem domain polypeptides, methods for providing hemagglutinin stem domain polypeptides, compositions comprising the same, vaccines comprising the same and methods of their use, in particular in the detection, prevention and/or treatment of influenza.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: June 25, 2019
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Antonietta Impagliazzo, Jan Willem Meijberg, Katarina Radosevic, Michelle Wagner, Zhaoqing Ding
  • INFLUENZA VIRUS VACCINES AND USES THEREOF
    Publication number: 20190015500
    Abstract: Provided herein are influenza hemagglutinin stem domain polypeptides, methods for providing hemagglutinin stem domain polypeptides, compositions comprising the same, vaccines comprising the same and methods of their use, in particular in the detection, prevention and/or treatment of influenza
    Type: Application
    Filed: September 25, 2018
    Publication date: January 17, 2019
    Inventors: Antonietta IMPAGLIAZZO, Jan Willem MEIJBERG, Katarina RADOSEVIC, Michelle WAGNER, Zhaoqing DING
  • Influenza virus vaccines and uses thereof
    Patent number: 10117925
    Abstract: Provided herein are multimeric influenza hemagglutinin stem domain polypeptides, methods for providing hemagglutinin stem domain polypeptides, compositions comprising the same, vaccines comprising the same and methods of their use, in particular in the detection, prevention and/or treatment of influenza.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: November 6, 2018
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Antonietta Impagliazzo, Jan Willem Meijberg, Katarina Radosevic, Michelle Wagner, Zhaoqing Ding
  • Influenza virus vaccines and uses thereof
    Patent number: 10111944
    Abstract: Provided herein are influenza hemagglutinin stem domain polypeptides, methods for providing hemagglutinin stem domain polypeptides, compositions comprising the same, vaccines comprising the same and methods of their use, in particular in the detection, prevention and/or treatment of influenza.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: October 30, 2018
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Antonietta Impagliazzo, Jan Willem Meijberg, Katarina Radosevic, Michelle Wagner, Zhaoqing Ding
  • INFLUENZA VIRUS VACCINES AND USES THEREOF
    Publication number: 20170209564
    Abstract: Provided herein are influenza hemagglutinin stem domain polypeptides, methods for providing hemagglutinin stem domain polypeptides, compositions comprising the same, vaccines comprising the same and methods of their use, in particular in the detection, prevention and/or treatment of influenza
    Type: Application
    Filed: July 9, 2015
    Publication date: July 27, 2017
    Inventors: Antonietta IMPAGLIAZZO, Jan Willem MEIJBERG, Katarina RADOSEVIC, Michelle WAGNER, Zhaoqing DING
  • INFLUENZA VIRUS VACCINES AND USES THEREOF
    Publication number: 20170189519
    Abstract: Provided herein are multimeric influenza hemagglutinin stem domain polypeptides, methods for providing hemagglutinin stem domain polypeptides, compositions comprising the same, vaccines comprising the same and methods of their use, in particular in the detection, prevention and/or treatment of influenza
    Type: Application
    Filed: July 9, 2015
    Publication date: July 6, 2017
    Inventors: Antonietta IMPAGLIAZZO, Jan Willem MEIJBERG, Katarina RADOSEVIC, Michelle WAGNER, Zhaoqing DING
  • INFLUENZA VIRUS VACCINES AND USES THEREOF
    Publication number: 20160136262
    Abstract: Provided are influenza hemagglutinin stem domain polypeptides comprising (a) an influenza hemagglutinin HA1 domain that comprises an HA1 N-terminal stem segment comprising the amino acids from position 1 to position x, preferably from position p to position x, of the HA1 domain, covalently linked by a linking sequence of 0-50 amino acid residues to an HA1 C-terminal stem segment, comprising the amino acids from position y to and including the C-terminal amino acid of the HA1 domain; and (b) an influenza hemagglutinin HA2 domain, wherein the hemagglutinin stem domain polypeptide is resistant to protease cleavage at the junction between HA1 and HA2, and wherein one or more amino acid of the amino acids at positions 337, 340, 352, 353, 402, 406, 409, 413 and/or 416 have been mutated, as compared to the corresponding positions in wild-type influenza HA.
    Type: Application
    Filed: November 25, 2015
    Publication date: May 19, 2016
    Inventors: Jan Willem Meijberg, Antonietta Impagliazzo, Katarina Radosevic, Jehangir Wadia, Robert Anthony Williamson, Michelle Wagner, Zhaoqing Ding