Abstract: The subject invention features methods for predicting whether a subject at risk of developing Acute Respiratory Distress Syndrome (ARDS) will develop ARDS by determining the amount of elafin present in a subject sample, or by determining the ration of elafin:neutrophil elastase in a subject sample. The invention also features methods for monitoring the efficacy of a treatment regimen for ARDS as well as methods of treatment for ARDS. The invention also features methods to determine a subject's predisposition for developing ARDS by determining whether certain genomic polymorphisms are present in the subject's DNA.

Abstract: A method for reconstructing the acoustic field on the surface of a vibrating object based on measurements of the radiated acoustic pressure includes solving the Helmholtz equation directly using the expansion of a set of independent functions that are generated by the Gram-Schmidt orthonormalization with respect to the particular solutions to the Helmholtz equation. The coefficients associated with these independent functions are determined by requiring the assumed form of solution to satisfy the pressure boundary condition at the measurement points. The errors involved in these coefficients are minimized by the least squares method. Once these coefficients are specified, the acoustic pressure at any point, including the source surface, is completely determined.