Patents by Inventor Zhaoxiong CAI

Zhaoxiong CAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ELASTASE INHIBITOR PRODRUG AND USE THEREOF
    Publication number: 20230107378
    Abstract: The present disclosure provides an elastase inhibitor prodrug and use thereof, being a compound of formula I or a pharmaceutically acceptable salt, ester, isomer or solvate thereof, prodrugs or isotopically labeled compound. Compared with the compound 52 (control example) in WO 2018/175173 A1, the compound disclosed herein has the advantages of high pulmonary exposure and long half-life. The prodrugs of the present disclosure significantly increase the concentration and residence time of the active compound (control example) in the lungs with significant improvements in pharmacokinetics in vivo compared to the control example.
    Type: Application
    Filed: March 8, 2021
    Publication date: April 6, 2023
    Inventors: Cheng PENG, Yang ZHOU, Yanfei WANG, Mengfei QIAN, Zhaoxiong CAI, Gang ZOU, Haiqing YUAN, Zhen Jim WU
  • Dihydroisoquinoline compound
    Patent number: 10647712
    Abstract: A compound of general formula I: is disclosed. The compound be used to prevent or treat hepatitis B virus infection.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: May 12, 2020
    Assignee: SUZHOU ARK BIOPHARMACEUTICAL CO., LTD.
    Inventors: Cheng Peng, Qing Xu, Teng Feng, Xiashi Lv, Xiaogang Lai, Rui Cui, Shaoyun Zhang, Jian Han, Chaojun Gong, Zhaoxiong Cai, Yang Zhou, Gang Zou, Danbin Li, Haiqing Yuan, Zhen Jim Wu
  • DIHYDROISOQUINOLINE COMPOUND
    Publication number: 20190389855
    Abstract: A compound of general formula I: is disclosed. The compound be used to prevent or treat hepatitis B virus infection.
    Type: Application
    Filed: January 10, 2018
    Publication date: December 26, 2019
    Inventors: Cheng PENG, Qing XU, Teng FENG, Xiashi LV, Xiaogang LAI, Rui CUI, Shaoyun ZHANG, Jian HAN, Chaojun GONG, Zhaoxiong CAI, Yang ZHOU, Gang ZOU, Danbin LI, Haiqing YUAN, Zhen Jim WU