Abstract: A method for performing real-time magnetic resonance (MR) imaging on a subject is disclosed. A prep pulse sequence is applied to the subject to obtain a high-quality special subspace, and a direct linear mapping from k-space training data to subspace coordinates. A live pulse sequence is then applied to the subject. During the live pulse sequence, real-time images are constructed using a fast matrix multiplication procedure on a single instance of the k-space training readout (e.g., a single k-space line or trajectory), which can be acquired at a high temporal rate.

Abstract: A method of performing multidimensional magnetic resonance imaging on a subject comprises collecting imaging data for a region of interest of the subject, the imaging data related to one or more spatially-varying parameters of the subject within the region of interest; collecting auxiliary data for the region of interest in the subject, the auxiliary data related to one or more time-varying parameters of the subject within the region of interest; linking the imaging data and the auxiliary data; and constructing an image tensor with one or more temporal dimensions based on at least a portion of the linked imaging data and at least a portion of the linked auxiliary data.

Abstract: A method for performing magnetic resonance imaging on a subject comprises: injecting a contrast agent into a region of interest of the subject; applying a pulse sequence to the region of interest; collecting auxiliary data for the region of interest, the auxiliary data being related to one or more time-varying parameters of the subject within the region of interest; determining a temporal factor ? from the auxiliary data; collecting imaging data for the region of interest, the imaging data being related to one or more spatially-varying parameters of the subject within the region of interest; determining a spatial factor Ur from the imaging data; modeling a multi-dimensional image sequence as I=Ur?; and deriving at least a first metric and a second metric from the multi-dimensional image sequence I, the first metric and the second metric being associated with distinct perfusion-based imaging techniques.

Abstract: A method for performing real-time magnetic resonance (MR) imaging on a subject is disclosed. A prep pulse sequence is applied to the subject to obtain a high-quality special subspace, and a direct linear mapping from k-space training data to subspace coordinates. A live pulse sequence is then applied to the subject. During the live pulse sequence, real-time images are constructed using a fast matrix multiplication procedure on a single instance of the k-space training readout (e.g., a single k-space line or trajectory), which can be acquired at a high temporal rate.

Abstract: A separator for a lithium-based battery, and method for fabricating the same is disclosed. The method includes oxidizing cellulose fibrils to form oxidized cellulose having carboxylic functional groups, decorating the oxidized cellulose with nanoparticles, and forming the nanoparticle-decorated oxidized cellulose into a film to become the separator for the lithium-based battery. The cellulose may be a bacterial cellulose. The cellulose fibrils may be oxidized through a TEMPO oxidation. Decorating the oxidized cellulose with nanoparticles may include introducing a precursor solution to the oxidized cellulose that reacts with hydroxyl groups of the oxidized cellulose while preserving the carboxylic functional groups, causing the nanoparticles to nucleate on the surface of the oxidized cellulose. The nanoparticles may be composed of an oxide material. The oxide material may be SiO2. The precursor solution may be tetraethyl orthosilicate (TEOS).

Abstract: A method of performing multidimensional magnetic resonance imaging on a subject comprises collecting imaging data for a region of interest of the subject, the imaging data related to one or more spatially-varying parameters of the subject within the region of interest; collecting auxiliary data for the region of interest in the subject, the auxiliary data related to one or more time-varying parameters of the subject within the region of interest; linking the imaging data and the auxiliary data; and constructing an image tensor with one or more temporal dimensions based on at least a portion of the linked imaging data and at least a portion of the linked auxiliary data.

Abstract: A method of performing multidimensional magnetic resonance imaging on a subject comprises collecting imaging data for a region of interest of the subject, the imaging data related to one or more spatially-varying parameters of the subject within the region of interest; collecting auxiliary data for the region of interest in the subject, the auxiliary data related to one or more time-varying parameters of the subject within the region of interest; linking the imaging data and the auxiliary data; and constructing an image tensor with one or more temporal dimensions based on at least a portion of the linked imaging data and at least a portion of the linked auxiliary data.

Abstract: High-frequency supercapacitors that can respond at kilohertz frequencies (AC-supercapacitors). The electrodes of the AC-supercapacitors include edge oriented graphene (EOG) electrodes or carbon nanofiber network (CNN) electrodes. The EOG electrodes are formed by utilizing a plasma and feedstock carbon gas to carbonize cellulous paper and deposit graphene implemented in one step. The CNN electrodes are formed by pyrolyzing a carbon nanofiber network utilizing a plasma.

Abstract: Magnetic resonance imaging utilizing a continuous spoiled gradient echo sequence with 3D radial trajectory and 1D self-gating for respiratory motion detection can be used to characterize respirator motion in the abdomen. The resulting image data is acquired and is retrospectively sorted into different respiratory phases based on their temporal locations within a respiratory cycle, and each phase is reconstructed via a self-calibrating conjugate gradient sensitivity encoding (CG-SENSE) program.

Abstract: High-frequency supercapacitors that can respond at kilohertz frequencies (AC-supercapacitors). The electrodes of the AC-supercapacitors include edge oriented graphene (EOG) electrodes or carbon nanofiber network (CNN) electrodes. The EOG electrodes are formed by utilizing a plasma and feedstock carbon gas to carbonize cellulous paper and deposit graphene implemented in one step. The CNN electrodes are formed by pyrolyzing a carbon nanofiber network utilizing a plasma.

Abstract: Embodiments of the present disclosure pertain to delivery agents for delivering one or more active agents to desired cells (e.g., adipose stromal cells). The delivery agents generally include: (1) a particle; (2) one or more active agents carried by the particle; and (3) a targeting agent associated with the particle, where the targeting agent directs the delivery agent to the desired cells. Additional embodiments of the present disclosure pertain to methods for delivering active agents to adipose stromal cells through the use of the aforementioned delivery agents. In some embodiments, the methods include a step of associating the adipose stromal cells with the delivery agent such that the associating results in the delivery of the active agents into the adipose stromal cells. The associating can occur by administering the delivery agent to a subject for the treatment or prevention of obesity and related disorder or diseases in the subject.

Abstract: High-frequency supercapacitors that can respond at kilohertz frequencies (AC-supercapacitors). The electrodes of the AC-supercapacitors include edge oriented graphene (EOG) electrodes or carbon nanofiber network (CNN) electrodes. The EOG electrodes are formed by utilizing a plasma and feedstock carbon gas to carbonize cellulous paper and deposit graphene implemented in one step. The CNN electrodes are formed by pyrolyzing a carbon nanofiber network utilizing a plasma.

Abstract: Embodiments can provide a computer-implemented method for free breathing three dimensional diffusion imaging, the method comprising initiating, via a k-space component processor, diffusion/T2 preparation, comprising generating diffusion contrast; and adjusting one or more of amplitude, duration, and polarity to set a first order moment; applying, via an image data processor, a stack of stars k-space ordering, comprising acquiring a radial/spiral view for all members of a plurality of partitions in a partition-encoding direction; increasing an azimuthal angle until a complete set of radial/spiral views are sampled; and applying diffusion gradients along each of three axis simultaneously; and calculating, via the image data processor, an apparent diffusion coefficient map.

Abstract: A method for performing 3D body imaging includes performing a 3D MRI acquisition of a patient to acquire k-space data and dividing the k-space data into k-space data bins. Each bin includes a portion of the k-space data corresponding to a distinct breathing phase. 3D image sets are reconstructed from the bins, with each 3D image set corresponding to a distinct k-space data bin. For each bin other than a selected reference bin, forward and inverse transforms are calculated between the 3D image set corresponding to the bin and the 3D image set corresponding to the reference bin. Then, a motion corrected and averaged image is generated for each bin by (a) aligning the 3D image set from each other bin to the 3D image set corresponding to the bin using the transforms, and (b) averaging the aligned 3D image sets to yield the motion corrected and averaged image.

Abstract: A method of performing multidimensional magnetic resonance imaging on a subject comprises collecting imaging data for a region of interest of the subject, the imaging data related to one or more spatially-varying parameters of the subject within the region of interest; collecting auxiliary data for the region of interest in the subject, the auxiliary data related to one or more time-varying parameters of the subject within the region of interest; linking the imaging data and the auxiliary data; and constructing an image tensor with one or more temporal dimensions based on at least a portion of the linked imaging data and at least a portion of the linked auxiliary data.

Abstract: Embodiments can provide a computer-implemented method for free breathing three dimensional diffusion imaging, the method comprising initiating, via a k-space component processor, diffusion/T2 preparation, comprising generating diffusion contrast; and adjusting one or more of amplitude, duration, and polarity to set a first order moment; applying, via an image data processor, a stack of stars k-space ordering, comprising acquiring a radial/spiral view for all members of a plurality of partitions in a partition-encoding direction; increasing an azimuthal angle until a complete set of radial/spiral views are sampled; and applying diffusion gradients along each of three axis simultaneously; and calculating, via the image data processor, an apparent diffusion coefficient map.

Abstract: A magnetic resonance method and system are provided for providing improved 3D imaging of blood vessels and the like, which provides suppression of both blood and fat signals and is insensitive to subject motion, thereby facilitating improved visualization of vessel walls. The image data pulse sequence includes a plurality of pulse series, where each series includes a dark-blood sequence, a fat-suppression sequence, and a data readout sequence. Each data readout sequence samples a particular radial direction within each partition (Kz value) that passes through the Kz axis, and different radial orientations are sampled in subsequent series to provide a stack-of-stars sampling scheme.

Abstract: A method for performing 3D body imaging includes performing a 3D MRI acquisition of a patient to acquire k-space data and dividing the k-space data into k-space data bins. Each bin includes a portion of the k-space data corresponding to a distinct breathing phase. 3D image sets are reconstructed from the bins, with each 3D image set corresponding to a distinct k-space data bin. For each bin other than a selected reference bin, forward and inverse transforms are calculated between the 3D image set corresponding to the bin and the 3D image set corresponding to the reference bin. Then, a motion corrected and averaged image is generated for each bin by (a) aligning the 3D image set from each other bin to the 3D image set corresponding to the bin using the transforms, and (b) averaging the aligned 3D image sets to yield the motion corrected and averaged image.

Abstract: In various embodiments, the present invention teaches systems and methods for using T1-weighted black-blood MR imaging, with which a CVT can be well isolated from the surrounding tissues due to the signal suppression of flowing blood. In some embodiments, the invention teaches using black-blood imaging (3D variable-flip-angle turbo spin-echo acquisition) to directly visualize thrombi. In certain embodiments, the invention teaches using T1 weighted image contrast and isotropic sub-millimeter spatial resolution for accurate detection and staging of thrombi. In various embodiments, the invention allows for the detection of chronic thrombosis recanalization.

Abstract: The present invention relates to imaging and characterizing atherosclerotic lesions. The invention utilizes a low-flip-angle gradient echo-based MRI acquisition technique combined with specialized magnetization preparative schemes (i.e. non-selective inversion and FSD), and multiple co-registered 3D image sets with different contrast weightings are collected in an interleaved fashion. Using the inventive method, a single scan allows for comprehensive assessment of atherosclerotic plaque within just a few minutes.