Patents by Inventor Zhaozhao Zhang

Zhaozhao Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250114222
    Abstract: The present invention discloses a biodegradable molybdenum-based flow diverter and a preparation method thereof, wherein the preparation method comprises the following steps: step 1. pretreatment of a molybdenum wire: cleaning and drying the molybdenum wire, and then weaving to obtain the molybdenum-based flow diverter; step 2. performing heat treatment on the molybdenum-based flow diverter in the step 1; and step 3. performing surface chemical polishing treatment on the molybdenum-based flow diverter subjected to the heat treatment in the step 2. The present invention solves the technical problem that the flow diverter in the prior art cannot be degraded in vivo and therefore easily causing various complications. It provides also improved mechanical property, MRI magnetic resonance imaging (MRI) compatibility as well as biocompatibility, and particularly has the function of promoting rapid endothelialization, compared with other degradable materials.
    Type: Application
    Filed: September 10, 2024
    Publication date: April 10, 2025
    Inventors: GUOJIANG WAN, FEI GAO, YUKUN ZHOU, JINJING LIU, WENJIE TAO, ZHAOZHAO ZHANG
  • Patent number: 9718802
    Abstract: The present invention relates to novel crystal forms M and N of dabigatran etexilate mesylate and preparation method and uses thereof, wherein the X-Ray powder diffractogram of the crystal form M has characteristic peaks at the following 2? diffraction angles: 5.7±0.2°, 6.2±0.2°, 11.2±0.2°, 12.4±0.2°, 18.2±0.2°, 21.4±0.2°, 21.8±0.2° and 23.6±0.2°; and the X-Ray powder diffractogram of the crystal form N has characteristic peaks at the following 2? diffraction angles: 6.0±0.2°, 11.8±0.2°, 18.2±0.2°, 21.6±0.2°, 24.4±0.2°, 27.7±0.2° and 29.7±0.2°. The crystal forms of the present invention have excellent properties in the aspects of leaching time, biological release, chemical stability and processing adaptability.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: August 1, 2017
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Liang Zhang, Chuan Liu, Jinyi Xu, Zhaozhao Zhang, Zhi Chen, Jian Chai, Zhiqing Yang, Hairong Luo, Xiangyang Zhang
  • Publication number: 20170073327
    Abstract: The present invention relates to novel crystal forms M and N of dabigatran etexilate mesylate and preparation method and uses thereof, wherein the X-Ray powder diffractogram of the crystal form M has characteristic peaks at the following 2? diffraction angles: 5.7±0.2°, 6.2±0.2°, 11.2±0.2°, 12.4±0.2°, 18.2±0.2°, 21.4±0.2°, 21.8±0.2° and 23.6±0.2°; and the X-Ray powder diffractogram of the crystal form N has characteristic peaks at the following 20 diffraction angles: 6.0±0.2°, 11.8±0.2°, 18.2±0.2°, 21.6±0.2°, 24.4±0.2°, 27.7±0.2° and 29.7±0.2°. The crystal forms of the present invention have excellent properties in the aspects of leaching time, biological release, chemical stability and processing adaptability.
    Type: Application
    Filed: March 4, 2015
    Publication date: March 16, 2017
    Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Liang Zhang, Chuan Liu, Jinyi Xu, Zhaozhao Zhang, Zhi Chen, Jian Chai, Zhiqing Yang, Hairong Luo, Xiangyang Zhang