Patents by Inventor Zhaozhong Jia

Zhaozhong Jia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF SYK AND JAK PROTEIN KINASES
    Publication number: 20120130073
    Abstract: The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
    Type: Application
    Filed: October 7, 2011
    Publication date: May 24, 2012
    Applicant: Portola Pharmaceuticals, Inc.
    Inventors: Zhaozhong Jia, Chandrasekar Venkataramani, Wolin Huang, Mukund Mehrotra, Yonghong Song, Qing Xu, Shawn M. Bauer, Jack W. Rose, Brian Kane, Anjali Pandey
  • INHIBITORS OF SYK AND JAK PROTEIN KINASES
    Publication number: 20120101275
    Abstract: The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
    Type: Application
    Filed: October 17, 2011
    Publication date: April 26, 2012
    Applicant: Portola Pharmaceuticals, Inc.
    Inventors: Zhaozhong Jia, Chandrasekar Venkataramani, Wolin Huang, Mukund Mehrotra, Yonghong Song, Qing Xu, Shawn M. Bauer, Jack W. Rose, Brian Kane, Anjali Pandey
  • FACTOR XA INHIBITORS
    Publication number: 20110118244
    Abstract: The present invention is directed to compounds of formula (I) and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to intermediates used in making such compounds, pharmaceutical compositions containing such a compound, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
    Type: Application
    Filed: May 11, 2010
    Publication date: May 19, 2011
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Yonghong SONG, Zhaozhong JIA, Robert SCARBOROUGH, Anjali PANDEY
  • Inhibitors of syk and JAK protein kinases
    Publication number: 20100048567
    Abstract: The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
    Type: Application
    Filed: April 16, 2009
    Publication date: February 25, 2010
    Applicant: Portola Pharmaceuticals Inc.
    Inventors: Zhaozhong Jia, Chandrasekar Venkataramani, Wolin Huang, Mukund Mehrota, Yonghong Song, Qing Xu, Shawn M. Bauer, Jack W. Rose, Brian Kane, Anjali Pandey
  • FACTOR Xa INHIBITORS
    Publication number: 20070185092
    Abstract: The present invention is directed to compounds represented by Formula (I) or a pharmaceutically acceptable salt, ester, or prodrug thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
    Type: Application
    Filed: January 5, 2007
    Publication date: August 9, 2007
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Bing-Yan Zhu, Shawn Bauer, Zhaozhong Jia, Yonghong Song, Gary Probst, Yanchen Zhang, Robert Scarborough
  • Factor Xa inhibitors
    Publication number: 20060100193
    Abstract: The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
    Type: Application
    Filed: June 20, 2005
    Publication date: May 11, 2006
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Bing-Yan Zhu, Shawn Bauer, Zhaozhong Jia, Gary Probst, Yanchen Zhang, Robert Scarborough
  • 2,4-dioxo-3-quinazolinylaryl sulfonylureas
    Publication number: 20050107357
    Abstract: 2,4-Dioxo-3-quinazolinylaryl sulfonylurea compounds are provided that are useful for the inhibition of ADP-platelet aggregation, particularly in the treatment of thrombosis and thrombosis related conditions or disorders.
    Type: Application
    Filed: September 29, 2004
    Publication date: May 19, 2005
    Applicant: Portola Pharmaceuticals, Inc.
    Inventors: Robert Scarborough, Wolin Huang, Anjali Pandey, Shawn Bauer, Xiaoming Zhang, Zhaozhong Jia