Abstract: Provided are a display panel and a display device. The display panel includes a first substrate and a second substrate disposed opposite to each other, and a liquid crystal layer located between the first substrate and the second substrate. The first substrate is provided with a planarization layer. A surface of a side of the planarization layer facing the liquid crystal layer is provided with multiple groove structures and a protrusion structure located between adjacent groove structures, the second substrate is provided with color film structures which are arranged at intervals, and a color film structure at least partially overlaps with a groove structure in a thickness direction of the display panel. Multiple first support structures are disposed between the first substrate and the second substrate, and a first support structures and the planarization layer are disposed at intervals in the thickness direction of the display panel.

Abstract: A display panel and a display device are provided. The display panel includes: a display region, a non-display region, and multiple drive signal lines. A fanout region and a connection terminal region are disposed in the non-display region. Multiple fanout wires are arranged in the fanout region. Multiple connection terminals are arranged in the connection terminal region. The fanout wires include a first fanout wire and a second fanout wire. The first fanout wire includes a first wire segment. The first wire segment has a width different from the width of the second fanout wire. The length of the first wire segment is equal to at least a portion of the length of the first fanout wire.

Abstract: An array substrate, a method for manufacturing an array substrate, a display panel and a display device are provided. The array substrate includes a substrate; an insulating layer arranged at a side of the substrate, where the insulating layer is provided with an opening, the insulating layer includes a first area and a second area, a thickness of the first area is less than a thickness of the second area, and the first area is arranged around at least a part of the opening; and a first conductive part arranged at a side of the insulating layer away from the substrate, where an orthographic projection of the first conductive part on the substrate and an orthographic projection of the first area on the substrate are at least partially overlapped.

Abstract: Disclosed herein are a polypeptide having cephalosporin C(CPC) acylase activity and a use thereof. More specifically, a mutant CPC acylase comprising a point mutation introduced thereinto, thereby exhibiting improved enzymatic activity and/or stability, and a use of the mutant CPC acylase for producing 7-aminocephalosporanic acid (7-ACA), are provided.

Abstract: Provided are a display panel including multiple scan lines located in the display region and gate drive unit groups located in a non-display region. The gate drive unit groups include at least one first gate drive unit group and at least one second gate drive unit group. The first gate drive unit group includes multiple cascaded first gate drive units. The second gate drive unit group includes multiple cascaded second gate drive units. The first gate drive units and the second gate drive units are connected to different scan lines. A first period during which a first gate drive unit at the first stage transmits an effective level signal to a scan line and a second period during which a second gate drive unit at the first stage transmits an effective level signal to a scan line overlap, overlap duration is t, and t>0.

Abstract: Disclosed herein are a microorganism with excellent deacetoxycephalosporin C (DAOC) productivity and a use thereof. A mutant microorganism with improved DAOC productivity and a use thereof for producing 7-aminodeacetoxycephalosporanic acid (7-ADCA) are provided.

Abstract: Disclosed herein are a polypeptide having cephalosporin C(CPC) acylase activity and a use thereof. More specifically, a mutant CPC acylase comprising a point mutation introduced thereinto, thereby exhibiting improved enzymatic activity and/or stability, and a use of the mutant CPC acylase for producing 7-aminocephalosporanic acid (7-ACA), are provided.

Abstract: The present invention relates to a mutated immunoglobulin-binding protein having increased alkaline tolerance and, more specifically, to an immunoglobulin-binding protein in which, with respect to the A-domain of Staphylococcal protein A, or a functional variant thereof, an amino acid at a specific site is mutated and thereby exhibits an increased chemical stability at an alkaline pH value in comparison to a parental molecule. The present invention can provide an antibody-purifying immunoglobulin-binding protein ligand and matrix which have enhanced alkaline tolerance and accordingly enhanced stability in multiple times of alkaline cleaning.

Abstract: The present invention relates to a mutated immunoglobulin-binding protein having increased alkaline tolerance and, more specifically, to an immunoglobulin-binding protein in which, with respect to the A-domain of Staphylococcal protein A, or a functional variant thereof, an amino acid at a specific site is mutated and thereby exhibits an increased chemical stability at an alkaline pH value in comparison to a parental molecule. The present invention can provide an antibody-purifying immunoglobulin-binding protein ligand and matrix which have enhanced alkaline tolerance and accordingly enhanced stability in multiple times of alkaline cleaning.