Patents by Inventor Zheguang FAN

Zheguang FAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230321859
    Abstract: A knife holder is provided. The knife holder includes: a base; a pressure plate pivotally arranged to the base and configured to releasably clamp a blade in a sectioning position together with the base; and a blade changing apparatus embedded in the base and configured to output an unused blade out of the base to change a used blade.
    Type: Application
    Filed: September 10, 2020
    Publication date: October 12, 2023
    Inventors: Jue CHEN, Zheguang FAN, Hongjian TAO
  • Publication number: 20230324259
    Abstract: A microtome includes a blade; and a knife holder. The blade has a cutting edge configured to section a specimen block. The knife holder includes a base, a pressure plate and a frame. The pressure plate is connected to the base, and the pressure plate is adjustable relative to the base to clamp the blade between base and the pressure plate. The frame includes at least one limb and a bridge extending from the at least one limb parallel to the cutting edge. The bridge is proximate the cutting edge, the bridge and the blade cooperatively define a first gap therebetween, and the bridge and the pressure plate cooperatively define a second gap therebetween.
    Type: Application
    Filed: September 3, 2020
    Publication date: October 12, 2023
    Inventors: ZheGuang FAN, HongJian TAO, Song JIN, Alice ZHANG
  • Publication number: 20230256641
    Abstract: A blade moving device includes: a support base; a linear bushing arranged in the support base; a moving block received in the support base and movably fitted over the linear bushing; a touch connector connected to the moving block and configured to move along with the moving block; and a blade box connected to the support base and configured to receive a blade therein. The touch connector is further configured to touch and push the blade to move out of the blade box when moving along with the moving block.
    Type: Application
    Filed: October 30, 2019
    Publication date: August 17, 2023
    Inventors: Zheguang FAN, Hongjian TAO
  • Publication number: 20230243722
    Abstract: A blade roller device (100) includes a first blade roll unit (110), a second blade roll unit (120) spaced apart from the first blade roll unit (110), and a first rotate lever (130). The first blade roll unit (110) includes a first slewing mechanism (111) and a first blade roll (112) wound upon the first slewing mechanism (111). The second blade roll unit (120) includes a second slewing mechanism (121) coupled to the first rotate lever (130) and a second blade roll (122) formed by pulling a segment of the first blade roll (112) to the second slewing mechanism (121) and winding the segment of the first blade roll (112) upon the second slewing mechanism (121). A rotation of the first rotate lever (130) in a first direction is capable of pulling the segment of first blade roll (112) to the second slewing mechanism (121).
    Type: Application
    Filed: October 30, 2019
    Publication date: August 3, 2023
    Inventors: Zheguang FAN, Haixia ZHANG
  • Publication number: 20230236091
    Abstract: A blade clamping device for a microtome is provided. The blade clamping device includes: a base part; a pressure plate rotatably connected to the base part via a rotation shaft; a clamping pin received in the base part, and configured to extend out of the base part and push the pressure plate to rotate, so as to clamp a blade between the base part and the pressure plate; and a drive unit received in the base part, connected to the clamping pin and configured to drive the clamping pin to extend out of the base part.
    Type: Application
    Filed: October 31, 2019
    Publication date: July 27, 2023
    Inventors: Zheguang FAN, Song JIN
  • Patent number: 11668628
    Abstract: A retraction device includes a spindle movable along the axis thereof and an operating unit including a pull rod and a movable member. The movable member defines a step-shaped groove, the pull rod has a first end connected to the spindle, and a second end received in the groove; the groove includes a first step and a second step and an inclined face connecting the first step and the second step arranged along a first direction, and a height of the second step is greater than that of the first step along the axis direction of the spindle; the movable member is slidable along the first direction relative to the pull rod, to allow the spindle to switch between a retraction position in which the pull rod is received in the second step, and a release position in which the pull rod is received in the first step.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: June 6, 2023
    Assignee: Leica Microsystems Ltd., Shanghai
    Inventors: Zheguang Fan, Xiang Liang, Gang Zhou
  • Publication number: 20230076711
    Abstract: The present disclosure relates to a cutter holder for a microtome. The cutter holder includes: a base; a pressing plate pivotably mounted to the base and having a first end configured to clamp the cutter; an eccentric shaft rotatably mounted in the base; and a sliding assembly slidably mounted in the base. The sliding assembly is arranged between the pressing plate and the eccentric shaft and is in contact with the eccentric shaft, and the sliding assembly is movable towards the pressing plate when the eccentric shaft rotates, so as to force the first end of the pressing plate to clamp the cutter with the base. The cutter holder according to embodiments of the present disclosure allows easy mounting and replacement of the pressing plate, facilitates clamping of the cutter and regulation of a clamping force, and has high working efficiency and high reliability.
    Type: Application
    Filed: January 19, 2021
    Publication date: March 9, 2023
    Inventor: ZheGuang FAN
  • Publication number: 20220404237
    Abstract: The present disclosure provides a moving and clamping device (200) for a blade holder (100) of a microtome. The blade holder (100) includes a blade receptacle (120) configured to receive and clamp a blade. The moving and clamping device (200) includes a rotary member (210) and a clamping member (220). The rotary member (210) is configured to drive the blade receptacle (120) to move in a direction perpendicular to a rotating axis of the rotary member (210), and the clamping member (220) is configured to be movable in the rotating axis of the rotary member (210), so as to operatively clamp or release the blade receptacle (120). The rotary member (210) is rotatably fitted over the clamping member (220). The present disclosure further provides a blade holder (100).
    Type: Application
    Filed: November 11, 2019
    Publication date: December 22, 2022
    Inventor: Zheguang FAN
  • Publication number: 20220390331
    Abstract: The present disclosure provides a blade load mechanism for a blade holder of a microtome. The blade holder has a base defining a blade receptacle configured to receive a blade, the blade load mechanism includes a blade supply container configured to contain a blade therein, the blade supply container defining a removal opening through which the blade is able to be removed from the blade supply container, and a blade access slot through an outer wall of the blade supply container in a length direction of the blade; and a blade pusher configured to engage with the blade through the blade access slot and slide along the blade access slot to push the blade out of the blade supply container through the removal opening, and deliver the blade into the blade receptacle. The present disclosure further provides a blade unload mechanism and a blade changing system.
    Type: Application
    Filed: November 7, 2019
    Publication date: December 8, 2022
    Inventor: Zheguang FAN
  • Patent number: 11491677
    Abstract: A retraction device includes: a spindle, a support plate and a plurality of spring washers. The spindle is movable along an axis direction thereof and has a first end; a support plate has a fixed position, the first end of the spindle penetrates the support plate; and the plurality of spring washers are fitted over the first end of the spindle and stacked together in an identical direction. The plurality of spring washers are compressed between the spindle and the support plate with a predetermined pre-load. The spindle is configured to be switchable between a first position and a second position, and capable of moving a predetermined distance relative to the support plate in the axis direction of the spindle during switching. When in the first position, the spindle is farthest from the support plate, when in the second position, the spindle is closest to the support plate.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: November 8, 2022
    Assignee: Leica Microsystems Ltd., Shanghai
    Inventors: Zheguang Fan, Xiang Liang, Gang Zhou
  • Patent number: 11333582
    Abstract: The disclosure relates to a microtome having a cutting knife, an object holder mounted on a slide, the slide being movable relative to the cutting knife in a cutting direction and in a thickness defining direction, movement of the slide in the thickness defining direction being performed by a first electric motor controlled by a control unit, movement of the slide in the cutting direction being performed by a second electric motor controlled by the control unit, wherein the control unit is configured to control the movement of the slide in the thickness defining direction and in the cutting direction.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: May 17, 2022
    Assignee: LEICA BIOSYSTEMS NUSSLOCH GMBH
    Inventors: Zheguang Fan, Xiaoqi Jiang, Yunchao Yang, Song Jin, Xiang Liang, Jinyu Xu
  • Patent number: 11255758
    Abstract: A clamping device includes: an operating member; a wedge having a first inclined surface; a clamping member having a second inclined surface movable relative to the first inclined surface, the first and second inclined surfaces being provided in a face-to-face arrangement; and a housing having a first guiding part, a second guiding part and a chamber. The operating member is mounted in the first guiding part, the clamping member is mounted in the second guiding part, and the wedge is disposed in the chamber; the operating member is operated to move towards the wedge, such that the operating member contacts and pushes the wedge to move, and further the first inclined surface contacts and moves along the second inclined surface; whereby a pushing force of the operating member in a first direction is converted into a clamping force of the clamping member in a second direction.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: February 22, 2022
    Assignee: Leica Microsystems Ltd., Shanghai
    Inventors: Zheguang Fan, Xiangyu Hao, Xiaoqi Jiang
  • Patent number: 11209340
    Abstract: A rotary microtome and a control method therefore are provided. The rotary microtome includes: a specimen holder, configured to hold a specimen; a handwheel drive system, including a handwheel and a handwheel axis, and configured to receive a user operation via the handwheel and to move the specimen holder up and down via the handwheel axis based on the user operation; a damping component, connected to the handwheel axis, and configured to generate damping for rotation of the handwheel axis; a knife; a section motor, connected to the knife and configured to drive the knife to cut the specimen; and a control device, connected to the damping component and the section motor respectively, and configured to obtain an operation parameter of the section motor, and to adjust the damping generated by the damping component according to the operation parameter, such that the user feels a material hardness of the specimen.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: December 28, 2021
    Assignee: LEICA MICROSYSTEMS LTD., SHANGHAI
    Inventor: Zheguang Fan
  • Patent number: 11047770
    Abstract: A mass-balance means and a rotary microtome having the same are provided in the present disclosure. The mass-balance means includes: a connecting element, a first end of the connecting element being configured to be connected with a movable mass of the rotary microtome; a gear set having a preset gear ratio, a first end of the gear set being connected with a second end of the connecting element; an elastic element, the elastic element being pre-tensioned and adjustable, in which a first end of the elastic element is connected with a second end of the gear set for moving along with a rotation of the gear set so as to balance the movable mass.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: June 29, 2021
    Assignee: Leica Microsystems Ltd., Shanghai
    Inventors: Zheguang Fan, Xiangyu Hao, Xiaoqi Jiang
  • Publication number: 20200316805
    Abstract: A retraction device includes: a spindle, a support plate and a plurality of spring washers. The spindle is movable along an axis direction thereof and has a first end; a support plate has a fixed position, the first end of the spindle penetrates the support plate; and the plurality of spring washers are fitted over the first end of the spindle and stacked together in an identical direction. The plurality of spring washers are compressed between the spindle and the support plate with a predetermined pre-load. The spindle is configured to be switchable between a first position and a second position, and capable of moving a predetermined distance relative to the support plate in the axis direction of the spindle during switching. When in the first position, the spindle is farthest from the support plate, when in the second position, the spindle is closest to the support plate.
    Type: Application
    Filed: November 27, 2018
    Publication date: October 8, 2020
    Inventors: Zheguang FAN, Xiang LIANG, Gang ZHOU
  • Publication number: 20200307012
    Abstract: A retraction device includes a spindle movable along the axis thereof and an operating unit including a pull rod and a movable member. The movable member defines a step-shaped groove, the pull rod has a first end connected to the spindle, and a second end received in the groove; the groove includes a first step and a second step and an inclined face connecting the first step and the second step arranged along a first direction, and a height of the second step is greater than that of the first step along the axis direction of the spindle; the movable member is slidable along the first direction relative to the pull rod, to allow the spindle to switch between a retraction position in which the pull rod is received in the second step, and a release position in which the pull rod is received in the first step.
    Type: Application
    Filed: November 27, 2018
    Publication date: October 1, 2020
    Inventors: Zheguang FAN, Xiang LIANG, Gang ZHOU
  • Publication number: 20200217758
    Abstract: A rotary microtome and a control method therefore are provided. The rotary microtome includes: a specimen holder, configured to hold a specimen; a handwheel drive system, including a handwheel and a handwheel axis, and configured to receive a user operation via the handwheel and to move the specimen holder up and down via the handwheel axis based on the user operation; a damping component, connected to the handwheel axis, and configured to generate damping for rotation of the handwheel axis; a knife; a section motor, connected to the knife and configured to drive the knife to cut the specimen; and a control device, connected to the damping component and the section motor respectively, and configured to obtain an operation parameter of the section motor, and to adjust the damping generated by the damping component according to the operation parameter, such that the user feels a material hardness of the specimen.
    Type: Application
    Filed: September 26, 2018
    Publication date: July 9, 2020
    Inventor: Zheguang FAN
  • Patent number: D903893
    Type: Grant
    Filed: December 1, 2019
    Date of Patent: December 1, 2020
    Assignee: LEICA MICROSYSTEMS LTD. SHANGHAI
    Inventors: Gang Zhou, Jingtian Zhang, Zheguang Fan, Xiang Liang
  • Patent number: D903894
    Type: Grant
    Filed: December 1, 2019
    Date of Patent: December 1, 2020
    Assignee: LEICA MICROSYSTEMS LTD. SHANGHAI
    Inventors: Gang Zhou, Jingtian Zhang, Zheguang Fan, Xiang Liang
  • Patent number: D903895
    Type: Grant
    Filed: December 1, 2019
    Date of Patent: December 1, 2020
    Assignee: LEICA MICROSYSTEMS LTD. SHANGHAI
    Inventors: Gang Zhou, Jingtian Zhang, Zheguang Fan, Xiang Liang