Patents by Inventor Zhehui PENG

Zhehui PENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing bacterial polysaccharide-modified recombinant fusion protein and use of the protein
    Patent number: 10844098
    Abstract: The invention provided a method for preparing a bacterial polysaccharide-modified recombinant fusion protein and use of the bacterial polysaccharide-modified recombinant fusion protein. The method comprises: co-expressing a recombinant fusion protein and the Neisseria meningitidis O-oligosaccharyltransferase PglL in an O-antigen ligase gene-defective bacterium, and linking a polysaccharides endogenous or exogenous for the bacterium to the recombinant fusion protein by the O-oligosaccharyltransferase PglL, to obtain the bacterial polysaccharide-modified recombinant fusion protein. The protein can be used for preparing antibodies against bacterial polysaccharides and vaccines.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: November 24, 2020
    Assignee: Institute of Biotechnology, Academy of Military Medical Sciences, China
    Inventors: Jun Wu, Chao Pan, Peng Sun, Hengliang Wang, Bo Liu, Zhehui Peng, Li Zhu, Shaohong Chang, Xin Gong, Erling Feng, Bin Wang, Ming Zeng
  • Method for Preparing Bacterial Polysaccharide-Modified Recombinant Fusion Protein and Use of the Protein
    Publication number: 20180258145
    Abstract: The invention provided a method for preparing a bacterial polysaccharide-modified recombinant fusion protein and use of the bacterial polysaccharide-modified recombinant fusion protein. The method comprises: co-expressing a recombinant fusion protein and the Neisseria meningitidis O-oligosaccharyltransferase PglL in an O-antigen ligase gene-defective bacterium, and linking a polysaccharides endogenous or exogenous for the bacterium to the recombinant fusion protein by the O-oligosaccharyltransferase PglL, to obtain the bacterial polysaccharide-modified recombinant fusion protein. The protein can be used for preparing antibodies against bacterial polysaccharides and vaccines.
    Type: Application
    Filed: September 1, 2015
    Publication date: September 13, 2018
    Applicant: Institute of Biotechnology, Academy of Military Medical Sciences, China
    Inventors: Jun WU, Chao PAN, Peng SUN, Hengliang WANG, Bo LIU, Zhehui PENG, Li ZHU, Shaohong CHANG, Xin GONG, Erling FENG, Bin WANG, Ming ZENG