Patents by Inventor Zhehui ZHAO

Zhehui ZHAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHONDROITIN SULFATE POLYSACCHARIDE, AND SEMI-SYNTHETIC PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20220143074
    Abstract: The present invention relates to the technical field of medicine, in particular to a chondroitin sulfate polysaccharide, and a semi-synthetic preparation method therefor and the use thereof. A metal salt of the chondroitin sulfate polysaccharide provided by the present invention has an anti-inflammatory effect, and can be used for preparing a drug against inflammatory diseases. In particular, the metal salt of the chondroitin sulfate polysaccharide provided by the present invention has anti-inflammatory and bone-protecting effects, and can be used for preparing a drug against rheumatoid arthritis and for preparing a drug against osteoarthritis. The present invention provides a method for preparing the metal salt of the chondroitin sulfate polysaccharide, and the metal salt of the chondroitin sulfate polysaccharide with different degrees of sulfation can be obtained by semi-synthetic means in the present invention. The method is simple to operate and suitable for large-scale production.
    Type: Application
    Filed: March 5, 2020
    Publication date: May 12, 2022
    Applicant: Institute of Materia Medica, Chinese Academy of Medical Sciences
    Inventors: Zhehui ZHAO, Pingsheng LEI, Lianqiu WU, Shuang YANG, Wenjie WANG, Haijing ZHANG, Xiang LI