Abstract: Described is a polypeptide magnetic nanoparticle having a specific targeting polypeptide and a magnetic nanoparticle. The amino acid sequence of the specific targeting polypeptide is VRRDAPRFSMQGLDA-X, and the C-terminal X thereof is a sequence of 5 to 20 amino acids. The amino acid in the amino acid sequence of C-terminal X is selected from one or more of: C, G, and N. The polypeptide magnetic nanoparticle can be used for CTC detection and molecular typing of various cancer types, including esophageal cancer, liver cancer, lung cancer, stomach cancer, bladder cancer, skin cancer, melanoma, breast cancer, colorectal cancer, cervical cancer, etc. Biomarkers of CTC molecular typing include PD-L1, HER2, ER, PR, AR, EGFR, VEGFR, CXCR4, etc.

Abstract: The present disclosure provides a sleep monitoring garment and a sleep monitoring system. The sleep monitoring garment includes a wearable textile structure; a first monitoring band circumferentially extending along the wearable textile structure; a second monitoring band circumferentially extending along the wearable textile structure and with a distance to the first monitoring band; and an interface communicatively coupled with the first monitoring band and the second monitoring band.

Abstract: A polypeptide magnetic nanoparticle, comprising: a specific targeting polypeptide and a magnetic nanoparticle. The amino acid sequence of the specific targeting polypeptide is VRRDAPRFSMQGLDA-X, and the C-terminal X thereof is a sequence of 5 to 20 amino acids. The amino acid in the amino acid sequence of C-terminal X is selected from one or more of: C, G, and N. The polypeptide magnetic nanoparticle can be used for CTC detection and molecular typing of various cancer types, including esophageal cancer, liver cancer, lung cancer, stomach cancer, bladder cancer, skin cancer, melanoma, breast cancer, colorectal cancer, cervical cancer, etc. Biomarkers of CTC molecular typing include PD-L1, HER2, ER, PR, AR, EGFR, VEGFR, CXCR4, etc. The polypeptide magnetic nanoparticle is helpful for CTC detection and the qualitative and semiquantitative analysis of expression levels of biomarkers at CTC level, thereby performing precise therapy such as targeted individualized targeted therapy or immunotherapy on patients.

Abstract: The device has a short production line, and all components are reasonably configured. A multifunctional cooling control device is adopted to integrate high-pressure water descaling and intermediate billet cooling functions, which is simpler and more efficient. Layout of a 4R+(3?4)F rolling mill, four thermos-detectors and short-distance underground coilers are use. The method includes the steps: carrying out continuous casting to manufacture a slab, high-pressure water rotating descaling, rough rolling by a four-stand high reduction rough rolling unit, machining by a drum shear, cooling after high-pressure water descaling in the multifunctional cooling control device, finish rolling by a three-stand or four-stand finish rolling unit, air cooling, dividing coils by a high-speed flying shear, and coiling by underground coilers, wherein temperature monitoring is respectively carried out after rough rolling, before finish rolling, after finish rolling, and before coiling by the underground coiler.

Abstract: A wearable device and a system, the wearable device including a wearable textile body including a plurality of interwoven or knitted yarns; one or more textile sensors each located at an area on the wearable textile body, each textile sensor including a plurality of functional yarns integrally interwoven or knitted with the yarns of the wearable textile body at the located area; and an interface communicatively coupled with the one or more textile sensors.

Abstract: A communications device for forming a network node between two or more devices or systems. The communications device has a power supply connector for connecting to a power supply in a light socket of a lighting system thereby to power the communications device. The communications device depends from the light socket by the power supply connector. The communications device also includes a receiver for receiving incoming information from one or more first devices or systems, and a transmitter for transmitting outgoing information to one or more second devices or systems.

Abstract: A communications device for forming a network node between two or more devices or systems. The communications device has a power supply connector for connecting to a power supply in a light socket of a lighting system thereby to power the communications device. The communications device depends from the light socket by the power supply connector. The communications device also includes a receiver for receiving incoming information from one or more first devices or systems, and a transmitter for transmitting outgoing information to one or more second devices or systems.

Abstract: Timing of a global network of a circuit design is processed globally while modifications to the global network are associated with logical blocks of the circuit design. Accordingly, the global network can be divided at boundaries of the logical blocks after timing is optimized globally. Paths with the worst timing problems are processed first, and devices of the path which the largest delays are processed first. Improvements in a path's timing are achieved by replacing overloaded devices with bigger ones and/or by inserting buffers. Path segments though un-routed soft blocks are estimated by determining a density center of driven devices, determining a distance to the density center, and adding distances from the density center to each of the driven devices. Devices are categorized according to delays corresponding to driven capacitances. For each device delays are calculated and mapped for various driven capacitances and adjusted for the physical size of each device.