Patents by Inventor Zhen Hou

Zhen Hou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12619400
    Abstract: In some implementations, a system may obtain, using a configuration manager, a configuration file associated with a multi-layer model platform, the configuration file comprising one or more parameter values associated with one or more parameters, wherein the one or more parameters are associated with at least one data source, at least one model algorithm, a model structure, at least one model running environment, and at least one model dependency. The system may generate, using the configuration manager in association with the configuration file, a multi-layer model instance. The system may deploy the multi-layer model instance in the at least one model running environment.
    Type: Grant
    Filed: November 14, 2023
    Date of Patent: May 5, 2026
    Assignee: Capital One Services, LLC
    Inventors: Zhen Hou, Jake Lowell Blitch, Sreekanth Chinthagunta, Antonio Valdes Cento
  • Patent number: 12505902
    Abstract: An embodiment represents composition of molecules in a feedstock as a combination of individual molecule representations and molecular attribute representations. A representation of chemistry of a chemical reaction of the feedstock in a chemical reactor is then formulated based on the representations. Then, a simulation of the chemical reaction of the feedstock in the reactor is performed using the representations to determine composition of products of the reaction. A first subset of the products are represented as individual molecule represented products, and a second subset of the products are represented as attribute represented products. In turn, the attribute represented products of the second subset are sampled to determine individual molecule representations of the attribute represented products. As a consequence of the sampling, individual molecule representations of the first and second subsets of the products of the chemical reaction of the feedstock in the chemical reactor result.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: December 23, 2025
    Assignee: AspenTech Corporation
    Inventors: Zhen Hou, Darin Campbell
  • Publication number: 20250315722
    Abstract: Systems and methods for augmenting feature selection for a first machine learning model using feature interactions from a preliminary feature set used for a second model. In some aspects, the system receives a first candidate set of features to train a machine learning model. The system also receives a precursor feature set used to train a precursor machine learning model in preparation for the machine learning model. Using the first candidate set of features and the precursor feature set, the system trains an algorithm to produce an interaction matrix, wherein the interaction matrix indicates an explanative power of each feature when combined with other features. Based on the interaction matrix, the system generates a subset of features from the first candidate set of features and the precursor feature set using a selection program. The system thus trains the machine learning model to use the subset of features as input.
    Type: Application
    Filed: April 8, 2024
    Publication date: October 9, 2025
    Applicant: Capital One Services, LLC
    Inventors: Zhen HOU, Ruoyu SHAO
  • Publication number: 20250308641
    Abstract: Embodiments represent a composition of molecules, in a chemical feedstock as a probabilistic combination of (i) a subset of a plurality of structural attribute representations and (ii) a subset of a plurality of individual molecule representations. Then, representations of reaction paths and reaction kinetics are determined based on the plurality of structural attribute representations and the plurality of individual molecule representations. A simulation is automatically performed of a chemical process on the feedstock that results in a processed feedstock using (i) the subset of the plurality of structural attribute representations, (ii) the subset of the plurality of individual molecule representations, and (iii) the determined representations of the reaction paths and reaction kinetics.
    Type: Application
    Filed: March 29, 2024
    Publication date: October 2, 2025
    Inventors: Zhen Hou, Darin Campbell
  • Publication number: 20250232844
    Abstract: Described is a computer-implemented method for modeling an equilibrium separation in a chemical separator. The method can include representing a feedstock of the chemical separator as a collection of molecules, each molecule having a mole fraction. A cluster analysis is performed on the feedstock based on a property of the collection of molecules to generate thermodynamic lumps. A mapping identity table is generated that identifies each molecule of the collection of molecules in the feedstock. A simulation of a chemical separation of the thermodynamic lumps is performed. The mole fraction of molecules in a resultant first phase and the mole fraction of molecules in a resultant second phase is determined.
    Type: Application
    Filed: April 7, 2022
    Publication date: July 17, 2025
    Inventors: Zhen Hou, Lingxiang Li, Lili Yu, Shu Wang, Darin Campbell
  • Publication number: 20250156158
    Abstract: In some implementations, a system may obtain, using a configuration manager, a configuration file associated with a multi-layer model platform, the configuration file comprising one or more parameter values associated with one or more parameters, wherein the one or more parameters are associated with at least one data source, at least one model algorithm, a model structure, at least one model running environment, and at least one model dependency. The system may generate, using the configuration manager in association with the configuration file, a multi-layer model instance. The system may deploy the multi-layer model instance in the at least one model running environment.
    Type: Application
    Filed: November 14, 2023
    Publication date: May 15, 2025
    Inventors: Zhen HOU, Jake Lowell BLITCH, Sreekanth CHINTHAGUNTA, Antonio VALDES CENTO
  • Publication number: 20250139065
    Abstract: In some implementations, a system may obtain an object comprising a plurality of sub-objects. The system may identify a schema associated with serialization and deserialization of the object, the schema defining a plurality of mappings. Each mapping in the plurality of mappings may associate a respective set of sub-objects in the plurality of sub-objects with a file in a plurality of files. The system may process the object according to the schema to obtain the plurality of files. The system may provide an output including the plurality of files.
    Type: Application
    Filed: October 31, 2023
    Publication date: May 1, 2025
    Inventors: Jake Lowell BLITCH, Zhen HOU
  • Patent number: 12265212
    Abstract: A three-dimensional (3D) microscope includes various insertable components that facilitate multiple imaging and measurement capabilities. These capabilities include Nomarski imaging, polarized light imaging, quantitative differential interference contrast (q-DIC) imaging, motorized polarized light imaging, phase-shifting interferometry (PSI), and vertical-scanning interferometry (VSI).
    Type: Grant
    Filed: November 28, 2022
    Date of Patent: April 1, 2025
    Assignee: KLA-Tencor Corporation
    Inventors: James Jianguo Xu, Ken Kinsun Lee, Rusmin Kudinar, Ronny Soetarman, Hung Phi Nguyen, Zhen Hou
  • Publication number: 20230087619
    Abstract: A three-dimensional (3D) microscope includes various insertable components that facilitate multiple imaging and measurement capabilities. These capabilities include Nomarski imaging, polarized light imaging, quantitative differential interference contrast (q-DIC) imaging, motorized polarized light imaging, phase-shifting interferometry (PSI), and vertical-scanning interferometry (VSI).
    Type: Application
    Filed: November 28, 2022
    Publication date: March 23, 2023
    Inventors: James Jianguo Xu, Ken Kinsun Lee, Rusmin Kudinar, Ronny Soetarman, Hung Phi Nguyen, Zhen Hou
  • Publication number: 20230049366
    Abstract: The present disclosure provides circulation system and method for detecting immune adherence of porcine erythrocytes. The system includes: a flow chamber, a gasket, a mobile-phase liquid storage bottle, a peristaltic pump, silicone hoses, and a cell culture dish provided with a glass slide, where the gasket is placed on an edge of the glass slide, and the flow chamber is covered on the gasket; the flow chamber, the mobile-phase liquid storage bottle, and the peristaltic pump are connected in sequence with the silicone hoses to form the circulation system; and a porcine erythrocyte suspension of immune adherence-sensitized GFP-E. coli is injected into the mobile-phase liquid storage bottle. In the present disclosure, the circulation system and method for detecting immune adherence of porcine erythrocytes can be used for detection and analysis of working parameters such as a mobile phase flow velocity, a shear force, and a maximum retention time.
    Type: Application
    Filed: August 4, 2022
    Publication date: February 16, 2023
    Inventors: Hongquan Li, Zhen Hou, Wei Yin, Kuohai Fan, Na Sun, Panpan Sun, Yaogui Sun
  • Patent number: 11536940
    Abstract: A three-dimensional (3D) microscope includes various insertable components that facilitate multiple imaging and measurement capabilities. These capabilities include Nomarski imaging, polarized light imaging, quantitative differential interference contrast (q-DIC) imaging, motorized polarized light imaging, phase-shifting interferometry (PSI), and vertical-scanning interferometry (VSI).
    Type: Grant
    Filed: December 2, 2020
    Date of Patent: December 27, 2022
    Assignee: KLA-Tencor Corporation
    Inventors: James Jianguo Xu, Ken Kinsun Lee, Rusmin Kudinar, Ronny Soetarman, Hung Phi Nguyen, Zhen Hou
  • Patent number: 11294161
    Abstract: A three-dimensional (3D) microscope includes various insertable components that facilitate multiple imaging and measurement capabilities. These capabilities include Nomarski imaging, polarized light imaging, quantitative differential interference contrast (q-DIC) imaging, motorized polarized light imaging, phase-shifting interferometry (PSI), and vertical-scanning interferometry (VSI).
    Type: Grant
    Filed: December 2, 2020
    Date of Patent: April 5, 2022
    Assignee: KLA-Tencor Corporation
    Inventors: James Jianguo Xu, Ken Kinsun Lee, Rusmin Kudinar, Ronny Soetarman, Hung Phi Nguyen, Zhen Hou
  • Patent number: 11219426
    Abstract: A method and system for determining an irradiation dose. The method for determining the irradiation dose includes determining a pixel having a biological feature in a region of interest in a radiotherapy simulated locating image by using a retrospective label; extracting a local radiomics feature based on the pixel having the biological feature, in which the local radiomics feature includes a grayscale histogram intensity, a tumor shape feature, a textural feature, a Laplacian of Gaussian filtering feature, and a wavelet feature; acquiring the local radiomics features to be measured; identifying a positive region having the local radiomics features to be measured based on the local radiomics features; performing three-dimensional reconstruction for the peripheral boundary of the positive region to determine a three-dimensional image.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: January 11, 2022
    Assignees: Tumor Hospital of Shandong First Medical University (Shandong Cancer Hospital and Institute
    Inventors: Jian Zhu, Zhen Hou, Zhenjiang Li, Haining Yu, Tong Bai, Yong Yin, Baosheng Li
  • Patent number: 11141127
    Abstract: A method and system for determining an irradiation dose. The method for determining the irradiation dose includes determining a pixel having a biological feature in a region of interest in a radiotherapy simulated locating image by using a retrospective label; extracting a local radiomics feature based on the pixel having the biological feature, in which the local radiomics feature includes a grayscale histogram intensity, a tumor shape feature, a textural feature, a Laplacian of Gaussian filtering feature, and a wavelet feature; acquiring the local radiomics features to be measured; identifying a positive region having the local radiomics features to be measured based on the local radiomics features; performing three-dimensional reconstruction for the peripheral boundary of the positive region to determine a three-dimensional image.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: October 12, 2021
    Assignees: Tumor Hospital of Shandong First Medical University
    Inventors: Jian Zhu, Zhen Hou, Zhenjiang Li, Haining Yu, Tong Bai, Yong Yin, Baosheng Li
  • Publication number: 20210217497
    Abstract: An embodiment represents composition of molecules in a feedstock as a combination of individual molecule representations and molecular attribute representations. A representation of chemistry of a chemical reaction of the feedstock in a chemical reactor is then formulated based on the representations. Then, a simulation of the chemical reaction of the feedstock in the reactor is performed using the representations to determine composition of products of the reaction. A first subset of the products are represented as individual molecule represented products, and a second subset of the products are represented as attribute represented products. In turn, the attribute represented products of the second subset are sampled to determine individual molecule representations of the attribute represented products. As a consequence of the sampling, individual molecule representations of the first and second subsets of the products of the chemical reaction of the feedstock in the chemical reactor result.
    Type: Application
    Filed: January 10, 2020
    Publication date: July 15, 2021
    Inventors: Zhen Hou, Darin Campbell
  • Publication number: 20210088768
    Abstract: A three-dimensional (3D) microscope includes various insertable components that facilitate multiple imaging and measurement capabilities. These capabilities include Nomarski imaging, polarized light imaging, quantitative differential interference contrast (q-DIC) imaging, motorized polarized light imaging, phase-shifting interferometry (PSI), and vertical-scanning interferometry (VSI).
    Type: Application
    Filed: December 2, 2020
    Publication date: March 25, 2021
    Inventors: James Jianguo Xu, Ken Kinsun Lee, Rusmin Kudinar, Ronny Soetarman, Hung Phi Nguyen, Zhen Hou
  • Publication number: 20210080710
    Abstract: A three-dimensional (3D) microscope includes various insertable components that facilitate multiple imaging and measurement capabilities. These capabilities include Nomarski imaging, polarized light imaging, quantitative differential interference contrast (q-DIC) imaging, motorized polarized light imaging, phase-shifting interferometry (PSI), and vertical-scanning interferometry (VSI).
    Type: Application
    Filed: December 2, 2020
    Publication date: March 18, 2021
    Inventors: James Jianguo Xu, Ken Kinsun Lee, Rusmin Kudinar, Ronny Soetarman, Hung Phi Nguyen, Zhen Hou
  • Patent number: 10884228
    Abstract: A three-dimensional (3D) microscope includes various insertable components that facilitate multiple imaging and measurement capabilities. These capabilities include Nomarski imaging, polarized light imaging, quantitative differential interference contrast (q-DIC) imaging, motorized polarized light imaging, phase-shifting interferometry (PSI), and vertical-scanning interferometry (VSI).
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: January 5, 2021
    Assignee: KLA-Tencor Corporation
    Inventors: James Jianguo Xu, Ken Kinsun Lee, Rusmin Kudinar, Ronny Soetarman, Hung Phi Nguyen, Zhen Hou
  • Publication number: 20190350550
    Abstract: A method and system for determining an irradiation dose. The method for determining the irradiation dose includes determining a pixel having a biological feature in a region of interest in a radiotherapy simulated locating image by using a retrospective label; extracting a local radiomics feature based on the pixel having the biological feature, in which the local radiomics feature includes a grayscale histogram intensity, a tumor shape feature, a textural feature, a Laplacian of Gaussian filtering feature, and a wavelet feature; acquiring the local radiomics features to be measured; identifying a positive region having the local radiomics features to be measured based on the local radiomics features; performing three-dimensional reconstruction for the peripheral boundary of the positive region to determine a three-dimensional image.
    Type: Application
    Filed: July 18, 2018
    Publication date: November 21, 2019
    Applicant: Shandong Cancer Hospital and Institute
    Inventors: Jian ZHU, Zhen HOU, Zhenjiang LI, Haining YU, Tong BAI, Yong YIN, Baosheng LI
  • Publication number: 20190228843
    Abstract: A computer-implemented method and system for modeling chemical reaction in a chemical reactor is disclosed. The method and system employ a molecule-based equation-oriented approach. Local-stored pre-estimated thermodynamic properties are generated based on a set of homologous series of compounds defined by the method and system. A set of reaction rate equations is automatically generated in equation-oriented format based on the defined set of homologous series of compounds, a system-defined set of permissible reactions, system-defined properties of the reactor compounds, and the locally-stored pre-estimated thermodynamic properties. The automatically generated set of reaction rate equations forms the model of chemical reactions in the chemical reactor.
    Type: Application
    Filed: January 17, 2019
    Publication date: July 25, 2019
    Inventors: Zhen Hou, Darin Campbell