Patents by Inventor Zhen Zeng

Zhen Zeng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210403557
    Abstract: The present invention relates to dosing regimens of an anti-TIGIT antibody useful for the treatment of cancer. In particular, the invention relates to the dosing regimen in a combination therapy which comprises administering an antibody of a Programmed Death 1 protein (PD-1) or Programmed Death Ligand 1 (PD-L1) and an anti-TIGIT antibody.
    Type: Application
    Filed: November 4, 2019
    Publication date: December 30, 2021
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Mingmei Cai, Elliot K. Chartash, Jane Anne Healy, Mallika Lala, Tommy Ruosi Li, Kapil Mayawala, Raluca Andreia Predoiu, Sybil M.G. Williams, Zhen Zeng
  • Publication number: 20210399327
    Abstract: Disclosed herein are batteries and methods of making batteries. The batteries disclosed herein generally comprise a cathode, an electrolyte capable of conducting protons and/or hydronium ions, and an anode comprising a material capable of absorbing protons and/or hydronium ions, wherein (i) the cathode is in contact with a cathode substance, or (ii) the electrolyte comprises a reduced cathode substance, or (iii) the cathode is in contact with a cathode substance and the electrolyte comprises a reduced cathode substance, and wherein the cathode substance is an oxide of one or more metals or an oxide of a halide.
    Type: Application
    Filed: October 29, 2019
    Publication date: December 23, 2021
    Inventors: Chuan ZHAO, Haocheng GUO, Yachao ZENG, Wenhao REN, Zhen SU, Xuancheng PENG
  • Publication number: 20210338803
    Abstract: The present invention discloses a dual-molecular DNA vaccine composed of viral antigen and immunization coactivator, which relates to the technical field of biomedicine. The said vector is a DNA plasmid; the viral antigen is any viral immunogenic (antigen) molecule; the immunological activator is a kind of T cell costimulators. The vaccine disclosed in the present invention is that two gene fragments expressing the T cell costimulator and the viral antigen molecule are constructed into one plasmid DNA and will be co-expressed in a cell at the same time to activate the systemic immune response through the two signalings. The dual-molecular DNA vaccine also is a novel platform of vaccine technology, using for development of multiple vaccines to prevention from various infectious diseases. Especially, a dual-molecular DNA vaccine with the SARS-CoV-2 S antigen and T cell costimulator can be constructed through this technology platform to prevent and control global pandemic COVID-19.
    Type: Application
    Filed: May 14, 2020
    Publication date: November 4, 2021
    Inventors: Li YU, Zhen ZENG, Lian ZENG, Mei ZHANG
  • Patent number: 11113669
    Abstract: In various embodiments, tools and user interfaces are provided that cater to the way that many employees desire to view their human resources data and human resources related transactions. These tools can be configured to provide appropriate, distilled contextual information, and transparency to the employment situation of the employee.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: September 7, 2021
    Assignee: The PNC Financial Services Group, Inc.
    Inventors: Helen Anne Miles, Linda Griffith, Scott Paterson, Zhen Zeng, Jen M. Levin, Elizabeth A. Spenko
  • Publication number: 20210224467
    Abstract: Described embodiments provide a method, computer program product, and computer system for generating, by a computing device, a data file including at least one property from a first cascading style sheet (CSS) file, the at least one property defining a scripting language object. A scripting language file may be generated, the scripting language file may include a scripting language variable for the scripting language object. A second CSS file may be generated by replacing the at least one property from the data file with the scripting language variable of the scripting language file. An element of a webpage referenced by the scripting language object may be rendered based upon, at least in part, the scripting language variable of the second CSS file.
    Type: Application
    Filed: April 6, 2021
    Publication date: July 22, 2021
    Inventors: Zhen Zeng, Cheng Xie
  • Patent number: 10970469
    Abstract: Described embodiments provide a method, computer program product, and computer system for generating, by a computing device, a data file including at least one property from a first cascading style sheet (CSS) file, the at least one property defining a scripting language object. A scripting language file may be generated, the scripting language file may include a scripting language variable for the scripting language object. A second CSS file may be generated by replacing the at least one property from the data file with the scripting language variable of the scripting language file. An element of a webpage referenced by the scripting language object may be rendered based upon, at least in part, the scripting language variable of the second CSS file.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: April 6, 2021
    Assignee: Citrix Systems, Inc.
    Inventors: Zhen Zeng, Cheng Xie
  • Publication number: 20210019367
    Abstract: Described embodiments provide a method, computer program product, and computer system for generating, by a computing device, a data file including at least one property from a first cascading style sheet (CSS) file, the at least one property defining a scripting language object. A scripting language file may be generated, the scripting language file may include a scripting language variable for the scripting language object. A second CSS file may be generated by replacing the at least one property from the data file with the scripting language variable of the scripting language file. An element of a webpage referenced by the scripting language object may be rendered based upon, at least in part, the scripting language variable of the second CSS file.
    Type: Application
    Filed: August 19, 2019
    Publication date: January 21, 2021
    Inventors: Zhen ZENG, Cheng XIE
  • Publication number: 20200396089
    Abstract: Embodiments of this application relate to a digital certificate management method performed at a computer device. The method includes: receiving a digital certificate generation request submitted by a certificate application node; transmitting identification information to consensus authentication centers for certification to obtain certification results obtained by the consensus authentication centers from performing the certification according to the identification information; determining an identification result corresponding to the certificate application node according to the certification results of the consensus authentication centers; generating, when the certification succeeds, a target digital certificate corresponding to the certificate application node submitting the digital certificate generation request; and writing the target digital certificate as a transaction resource into a blockchain associated with the consensus authentication centers.
    Type: Application
    Filed: August 26, 2020
    Publication date: December 17, 2020
    Inventors: Rui GUO, Maocai LI, Jianjun ZHANG, Zhen ZENG, Zichao TANG, Jiguang LU
  • Publication number: 20200382326
    Abstract: Embodiments of this application relate to a digital certificate verification method and apparatus, a computer device, and a storage medium. The digital certificate verification method is performed by a authentication center, and include receiving a verification request for verifying a target digital certificate; obtaining a target transaction record corresponding to the target digital certificate from a blockchain, the target digital certificate being stored in the blockchain as a transaction resource; obtaining a target account type corresponding to the target transaction record, different account types corresponding to different certificate operation states; and determining a verification result corresponding to the target digital certificate according to the target account type.
    Type: Application
    Filed: August 19, 2020
    Publication date: December 3, 2020
    Inventors: Rui GUO, Maocai LI, Jianjun ZHANG, Zhen ZENG
  • Publication number: 20200374280
    Abstract: A platform for delivering secure web applications to a client browser. A software plug-in is provided configured for integration into a web browser. The plug-in includes: a request hook that intercepts web browser requests associated with a secure web application; a request processing system that redirects an request to access the secure web application to a network service, and then redirects subsequent HTTP requests to interact with the secure web application to the network service; and a package manager that receives a text-based data package from a customer domain server in response to the initial request and renders the secure web application in the web browser, and receives an updated text-based data package from the customer domain server in response to the subsequent HTTP request and renders updates to secure web application in the web browser.
    Type: Application
    Filed: June 7, 2019
    Publication date: November 26, 2020
    Inventors: Zhen Zeng, Hongfei Wu
  • Publication number: 20200374281
    Abstract: A network service, program product and method that manages secure web application delivery. A service is disclosed that includes an interface configured to receive a request for a secure web application from a plug-in integrated into a web browser on a client computing device, wherein the request further includes a user credential token. Also included is a token processor that evaluates the user credential token and determines an associated customer domain server provided by a back-end service and a transport service that establishes a secure channel with the customer domain server, and forwards the request to the associated customer domain server and receives back a text-based data package. Once generated, the text-based data package is forwarded to the plug-in in response to the request.
    Type: Application
    Filed: June 7, 2019
    Publication date: November 26, 2020
    Inventors: Zhen Zeng, Hongfei Wu
  • Patent number: 10733570
    Abstract: In various embodiments, tools and user interfaces are provided that cater to the way that many employees desire to view their human resources data and human resources related transactions. These tools can be configured to provide appropriate, distilled contextual information, and transparency to the employment situation of the employee.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: August 4, 2020
    Assignee: The PNC Financial Services Group, Inc.
    Inventors: Helen Anne Miles, Linda Griffith, Scott Paterson, Zhen Zeng, Jen M. Levin, Elizabeth A. Spenko
  • Patent number: 10704051
    Abstract: The present invention provides an expression element and an expression cassette to establish a novel vector therefrom. The expression element of the present invention has an effect of enhancing the expression level of the target gene so that is highly industrial valuable. Accordingly, the present vector is taken as a novel tool for genetic engineering.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: July 7, 2020
    Assignee: AGRICULTURAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Jiunn-Horng Lin, Jyh-Perng Wang, Zeng-Weng Chen, Chien-Yu Fang, Hao-Zhen Zeng, Jian-Fong Lai, Weng-Zeng Huang, Shih-Ling Hsuan
  • Publication number: 20200160264
    Abstract: A network computer system that determines metrics related to effort and cost on the part of deliverers who deliverer items for delivery orders. The network computer system can implement operations to facilitate or mitigate features that cause deliverers to expend effort or cost when completing delivery tasks.
    Type: Application
    Filed: November 15, 2018
    Publication date: May 21, 2020
    Inventors: Scott Silverman, Martin Ken Iyoya, Wenjun Zhao, Zhen Zeng
  • Patent number: 10602651
    Abstract: A system for tracking objects such as a printed circuit board (PCB) undergoing multiple manufacturing processes traceability system includes a coding unit, a scanning unit, and a reading unit and a database. The printed circuit board includes at least two inner copper foil substrates, subsequent substrates can be added. The coding unit marks identification and manufacturing stage codes on the inner copper foil substrate for through scanning by the scanning unit emitting X-rays. The reading unit can receive and parse the codes identified by the X-rays, and determine the previous or a next stage according to a predetermined encoding rule without risk of stage repetition or stage omission or product misplacement. The database stores standard identities and information as to manufacturing stages as a reference.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: March 24, 2020
    Assignees: Avary Holding (Shenzhen) Co., Limited., HongQiSheng Precision Electronics (QinHuangDao) Co., Ltd.
    Inventors: Fu-Sheng Luo, Pai-Hung Huang, Chien-Jui Lo, Yin-Zhen Zeng
  • Publication number: 20200090248
    Abstract: A network computing system can publish a collection of interactive items for a given geographical region. The network computing system can detect interactions with the interactive items by a population of users, where each interaction is associated with a location of the user, one or more food items identified for selection by the interaction, and one or more food preparation sources selected by the interaction. Additionally, the network computing system can determine an interest level for a food item or type at one or more sub-regions of the geographic region, based on at least a portion of the detected interactions.
    Type: Application
    Filed: August 13, 2019
    Publication date: March 19, 2020
    Inventors: Zhen Zeng, Martin Ken Iyoya, Brion McDonough
  • Publication number: 20190320565
    Abstract: A system for tracking objects such as a printed circuit board (PCB) undergoing multiple manufacturing processes traceability system includes a coding unit, a scanning unit, and a reading unit and a database. The printed circuit board includes at least two inner copper foil substrates, subsequent substrates can be added. The coding unit marks identification and manufacturing stage codes on the inner copper foil substrate for through scanning by the scanning unit emitting X-rays. The reading unit can receive and parse the codes identified by the X-rays, and determine the previous or a next stage according to a predetermined encoding rule without risk of stage repetition or stage omission or product misplacement. The database stores standard identities and information as to manufacturing stages as a reference.
    Type: Application
    Filed: July 31, 2018
    Publication date: October 17, 2019
    Inventors: FU-SHENG LUO, PAI-HUNG HUANG, CHIEN-JUI LO, YIN-ZHEN ZENG
  • Patent number: 10208093
    Abstract: The present invention provides a plasmid, method and kit for producing heat labile enterotoxin B-subunit based on a Bacillus subtilis expression system. By comparing with the conventional method in the art, the present invention has the advantages of high safety, good yield, and simplified process and is therefore favorable for the commercialization object of heat labile enterotoxin B-subunit in the application of vaccine adjuvant.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: February 19, 2019
    Assignee: AGRICULTURAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Jiunn-Horng Lin, Jyh-Perng Wang, Chien-Yu Fang, Zeng-Weng Chen, Ming-Wei Hsieh, Hao-Zhen Zeng, Jian-Fong Lai, Weng-Zeng Huang, Tzu-Ting Peng
  • Publication number: 20180216119
    Abstract: The present invention provides an expression element and an expression cassette to establish a novel vector therefrom. The expression element of the present invention has an effect of enhancing the expression level of the target gene so that is highly industrial valuable. Accordingly, the present vector is taken as a novel tool for genetic engineering.
    Type: Application
    Filed: December 29, 2014
    Publication date: August 2, 2018
    Applicant: Agricultural Technology Research Institute
    Inventors: Jiunn-Horng LIN, Jyh-Perng WANG, Zeng-Weng CHEN, Chien-Yu FANG, Hao-Zhen ZENG, Jian-Fong LAI, Weng-Zeng HUANG, Shih-Ling HSUAN
  • Patent number: D849016
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: May 21, 2019
    Assignee: Airbnb, Inc.
    Inventors: Kyle Trevor Pickering, Derek Elijah Bradley, Stephanie Bain, Zhen Zeng, Jason Reyes Mamaril, Katherine Marisa Dill, David Bradley Haynes, David Chad Thornton, Nirav Vikash Sanghani, Joseph Nicholas Gebbia, Brian Joseph Chesky, Paul Phillip Stafford, James John Cullen, Alexandra Lubomirsky