Patents by Inventor Zhen Zhu
Zhen Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220042584Abstract: A multi-mode continuously variable transmission with both speed coupling and torque coupling includes an engine-power input assembly, a hydraulic transmission assembly, a motor transmission assembly, a planetary gear assembly, an output member, a clutch assembly, and a brake assembly, wherein an output end of the planetary gear assembly is connected to the output member, the clutch assembly connects the engine-power input assembly, the hydraulic transmission assembly, and the motor transmission assembly to an input end of the planetary gear assembly, and the clutch assembly connects the engine-power input assembly to the hydraulic transmission assembly; and the clutch assembly and the brake assembly provide a continuously changing transmission ratio between the engine-power input assembly or/and the motor transmission assembly and the output member.Type: ApplicationFiled: August 14, 2020Publication date: February 10, 2022Applicant: JIANGSU UNIVERSITYInventors: Zhen ZHU, Longhui LAI, Yingfeng CAI, Juncheng WANG, Jiangyi HAN, Jianguo ZHU, Rong ZOU, Dehua SHI, Xing XU, Yulin DENG
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Publication number: 20220042587Abstract: A gear-double ring-hydraulic hybrid transmission device includes an input mechanism, a double ring series transmission mechanism, a hydraulic transmission mechanism, an output member, a front planetary gear mechanism, a middle planetary gear mechanism, a rear planetary gear mechanism, a clutch assembly, and a brake assembly. An output of the double ring series transmission mechanism is connected to the middle planetary gear mechanism. The clutch assembly connects the input mechanism to the double ring series transmission mechanism, the hydraulic transmission mechanism, and the front planetary gear mechanism, connects an output of the hydraulic transmission mechanism to the middle planetary gear mechanism, and connects an output of the rear planetary gear mechanism to the output member. The clutch assembly and the brake assembly provide a continuous transmission ratio between the input mechanism and the output member.Type: ApplicationFiled: August 14, 2020Publication date: February 10, 2022Applicant: JIANGSU UNIVERSITYInventors: Zhen ZHU, Xiang TIAN, Yingfeng CAI, Long CHEN, Changgao XIA, Juncheng WANG, Jiangyi HAN, Jianguo ZHU, Rong ZOU, Lingxin ZENG
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Publication number: 20220011214Abstract: Disclosed is a passive wireless device for microfluidic detection of multi-level droplets. A primary inductor channel and a secondary inductor channel each comprise two layers of inductance coils, and the inductance coils of the primary inductor channel and the secondary inductor channel are alternately arranged in each layer. A double-resonance circuit is formed after a liquid conductive material is injected. A first part of a detection channel is disposed between a primary capacitor channel, and a second part of a detection channel is disposed between a secondary capacitor channel. A reading device is used to read a resonant frequency of the double-resonance circuit, and perform detection according to the resonant frequency to obtain information of a corresponding first droplet group and/or second droplet group.Type: ApplicationFiled: April 26, 2020Publication date: January 13, 2022Applicant: Southeast UniversityInventors: Zhen ZHU, Mi WANG, Zhao ZHANG, Qingan HUANG
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Publication number: 20210384832Abstract: A switch-mode power supply (SMPS), an SMPS system and a power supply method for an SMPS system are disclosed. The SMPS controller includes an output-voltage power supply unit, a built-in energy storage unit and a logic control unit. The output-voltage power supply unit is configured to charge the built-in energy storage unit using an output voltage from the SMPS system so that the built-in energy storage unit can provide an operating voltage for the logic control unit. The use of a stand-off energy storage capacitor can be dispensed with, and the use of the output voltage as a power supply is enabled. As a result, significant reductions in overall and standby power dissipation are achieved. In addition, the SMPS controller may further include a high-voltage power supply unit, which provides a hybrid power supply solution, together with the output-voltage power supply unit.Type: ApplicationFiled: June 4, 2021Publication date: December 9, 2021Inventors: Rulong JIANG, Liqiang HU, Shungen SUN, Zhen ZHU, Xiaoru GAO, Yihui CHEN, Hong ZHANG, Pengfei LU
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Publication number: 20210372512Abstract: A gear-hydraulic-metal belt integrated multi-mode hydro-mechanical hybrid transmission device includes an input assembly, an output assembly, a metal belt transmission mechanism, a planetary gear assembly, a hydraulic transmission mechanism, a clutch assembly and a brake assembly. The input assembly is connected to the metal belt transmission mechanism, the planetary gear assembly and the hydraulic transmission mechanism. The metal belt transmission mechanism and the hydraulic transmission mechanism are connected to the planetary gear assembly. The planetary gear assembly is connected to the output assembly. The clutch assembly connects the input assembly to the metal belt transmission mechanism and the planetary gear assembly, and connects each of the metal belt transmission mechanism and the hydraulic transmission mechanism to the planetary gear assembly. The clutch assembly and the brake assembly provide a continuous transmission ratio between the input assembly and the output assembly.Type: ApplicationFiled: February 10, 2020Publication date: December 2, 2021Applicant: Jiangsu UniversityInventors: Zhen ZHU, Yingfeng CAI, Long CHEN, Xiang TIAN, Changgao XIA, Falin ZENG, Chaochun YUAN, Jiajia WANG, Xiaodong SUN, Dehua SHI
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Publication number: 20210356024Abstract: A hydro-mechanical transmission device with a dual-clutch transmission includes an input mechanism, a pump-controlled motor mechanism, an odd-numbered gear transmission mechanism, an even-numbered gear transmission mechanism, an output mechanism, and a jackshaft. The input mechanism is connected to the odd-numbered gear transmission mechanism and the even-numbered gear transmission mechanism that are connected in parallel, and is connected to an input end of the pump-controlled motor mechanism. An output end of the pump-controlled motor mechanism is connected, through the jackshaft, to the odd-numbered gear transmission mechanism and the even-numbered gear transmission mechanism that are connected in parallel, and is connected to the output mechanism. Switching among hydraulic transmission, hydro-mechanical transmission, and mechanical transmission modes between the input mechanism and the output mechanism is implemented by controlling combination and engagement/disengagement of clutches and a brake.Type: ApplicationFiled: February 26, 2020Publication date: November 18, 2021Applicant: JIANGSU UNIVERSITYInventors: Zhen ZHU, Yingfeng CAI, Long CHEN, Changgao XIA, Xiang TIAN, Jiajia WANG, Falin ZENG, Xiaodong SUN, Dehua SHI, Xing XU
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Publication number: 20210331575Abstract: A continuously variable transmission system for hybrid power multi-mode switching, includes an input component, an output component, a clutch assembly, a brake, a hydraulic transmission assembly and a planetary gear assembly, wherein the input component is connected with the hydraulic transmission assembly, the output component is connected with the planetary gear assembly, the clutch assembly connects the input component and the hydraulic transmission assembly to the planetary gear assembly respectively, and the brake and the clutch assembly provide a transmission ratio for continuous forwarding or backwarding continuously between the input component and the output component. The hydro-mechanical transmission is switched to mechanical transmission by increasing the displacement ratio of the hydraulic transmission assembly linearly or non-linearly.Type: ApplicationFiled: January 24, 2019Publication date: October 28, 2021Inventors: Zhen ZHU, Yingfeng CAI, Long CHEN, Changgao XIA, Jiangyi HAN, Dehua SHI, Feng WANG, Chaochun YUAN, Chaofeng PAN, Xing XU
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Patent number: 11155154Abstract: A multi-pump driven single-motor hydro-mechanical hybrid transmission device includes an input shaft, a planetary gear split mechanism, a hydraulic transmission system, a planetary gear convergence mechanism, and an output shaft. The input shaft is connected to the hydraulic transmission system and the planetary gear convergence mechanism through the planetary gear split mechanism. The hydraulic transmission system and the planetary gear convergence mechanism are both connected to the output shaft. The hydraulic transmission system includes a multi-pump driving mechanism, a fixed displacement motor mechanism, and a hydraulic transmission output mechanism. The multi-pump driving mechanism is connected to the fixed displacement motor mechanism. The fixed displacement motor mechanism is connected to the planetary gear convergence mechanism and is connected to the output shaft through the hydraulic transmission output mechanism.Type: GrantFiled: February 26, 2020Date of Patent: October 26, 2021Assignee: JIANGSU UNIVERSITYInventors: Long Chen, Zhen Zhu, Yingfeng Cai, Xiang Tian, Changgao Xia, Falin Zeng, Jiajia Wang, Dehua Shi, Chaochun Yuan, Xiaodong Sun
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Publication number: 20210323394Abstract: A multi-pump driven single-motor hydro-mechanical hybrid transmission device includes an input shaft, a planetary gear split mechanism, a hydraulic transmission system, a planetary gear convergence mechanism, and an output shaft. The input shaft is connected to the hydraulic transmission system and the planetary gear convergence mechanism through the planetary gear split mechanism. The hydraulic transmission system and the planetary gear convergence mechanism are both connected to the output shaft. The hydraulic transmission system includes a multi-pump driving mechanism, a fixed displacement motor mechanism, and a hydraulic transmission output mechanism. The multi-pump driving mechanism is connected to the fixed displacement motor mechanism. The fixed displacement motor mechanism is connected to the planetary gear convergence mechanism and is connected to the output shaft through the hydraulic transmission output mechanism.Type: ApplicationFiled: February 26, 2020Publication date: October 21, 2021Applicant: JIANGSU UNIVERSITYInventors: Long CHEN, Zhen ZHU, Yingfeng CAI, Xiang TIAN, Changgao XIA, Falin ZENG, Jiajia WANG, Dehua SHI, Chaochun YUAN, Xiaodong SUN
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Publication number: 20210259951Abstract: The present invention relates to transmucosal delivery systems, methods and kits that include agents to penetrate the mucus, stratified squamous epithelial layer, and basement membrane, to deliver a vasodilatory agent and active agent to the lamina propria and smooth muscle. The formulation of the present invention further includes having a mucolytic agent for thinning or decreasing viscosity of mucus; a solvent; a proteolytic agent that cleaves or fragments long chain proteins to create cellular spacing of the stratified squamous epithelial layer and/or basement membrane, a vasodilatory agent; and at least one active ingredient. The formulation allows for penetration of the active ingredient at the mucosal surface to the smooth muscle. The active ingredient, once at the smooth muscle, is delivered locally to the tissue or systemically to the blood stream.Type: ApplicationFiled: February 17, 2021Publication date: August 26, 2021Applicants: North Atlantic Holdings LLCInventors: John J. Masiz, Zhen Zhu
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Publication number: 20210245597Abstract: A hydro-mechanical hybrid transmission device and a control method thereof, including an input shaft, a split mechanism, a hydraulic transmission assembly, a mechanical transmission assembly, a convergence mechanism, and an output shaft, wherein the input shaft is connected, through the split mechanism, to the hydraulic transmission assembly and the mechanical transmission assembly, wherein the hydraulic transmission assembly and the mechanical transmission assembly are connected in parallel, and the hydraulic transmission assembly and the mechanical transmission assembly are each connected to the output shaft through the convergence mechanism. In the hydro-mechanical hybrid transmission device, planetary gear structures are combined with engagement/disengagement of brakes and clutches, to implement switching of power split and convergence structural forms.Type: ApplicationFiled: December 4, 2019Publication date: August 12, 2021Applicant: JIANGSU UNIVERSITYInventors: Zhen ZHU, Yingfeng CAI, Long CHEN, Changgao XIA, Jiangyi HAN, Xiang TIAN, Xiaodong SUN, Longhui LAI, Dehua SHI, Chaochun YUAN
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Patent number: 11072231Abstract: A hydro-mechanical hybrid transmission device and a control method thereof, including an input shaft, a split mechanism, a hydraulic transmission assembly, a mechanical transmission assembly, a convergence mechanism, and an output shaft, wherein the input shaft is connected, through the split mechanism, to the hydraulic transmission assembly and the mechanical transmission assembly, wherein the hydraulic transmission assembly and the mechanical transmission assembly are connected in parallel, and the hydraulic transmission assembly and the mechanical transmission assembly are each connected to the output shaft through the convergence mechanism. In the hydro-mechanical hybrid transmission device, planetary gear structures are combined with engagement/disengagement of brakes and clutches, to implement switching of power split and convergence structural forms.Type: GrantFiled: December 4, 2019Date of Patent: July 27, 2021Assignee: JIANGSU UNIVERSITYInventors: Zhen Zhu, Yingfeng Cai, Long Chen, Changgao Xia, Jiangyi Han, Xiang Tian, Xiaodong Sun, Longhui Lai, Dehua Shi, Chaochun Yuan
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Publication number: 20210102611Abstract: A hydro-mechanical hybrid transmission device and a control method thereof are provided. The device includes an input shaft, a split mechanism, a mechanical transmission assembly, a hydraulic transmission assembly, and an output shaft, wherein the input shaft is connected, through the split mechanism, to the mechanical transmission assembly and the hydraulic transmission assembly that are connected in parallel, and the mechanical transmission assembly and the hydraulic transmission assembly are both connected to the output shaft. The mechanical transmission assembly includes a front planetary-gear-set assembly and a rear planetary-gear-set assembly. The front planetary-gear-set assembly and the rear planetary-gear-set assembly are connected in series. The control method includes three modes of transmission: pure hydraulic transmission, hydro-mechanical hybrid transmission, and pure mechanical transmission are implemented through combination and engagement/disengagement of gear-shift components.Type: ApplicationFiled: October 23, 2019Publication date: April 8, 2021Applicant: JIANGSU UNIVERSITYInventors: Zhen ZHU, Yingfeng CAI, Long CHEN, Changgao XIA, Xiang TIAN, Jiangyi HAN, Xiaodong SUN, Dehua SHI, Feng WANG, Chaochun YUAN
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Patent number: 10955038Abstract: A hydro-mechanical hybrid transmission device and a control method thereof are provided. The device includes an input shaft, a split mechanism, a mechanical transmission assembly, a hydraulic transmission assembly, and an output shaft, wherein the input shaft is connected, through the split mechanism, to the mechanical transmission assembly and the hydraulic transmission assembly that are connected in parallel, and the mechanical transmission assembly and the hydraulic transmission assembly are both connected to the output shaft. The mechanical transmission assembly includes a front planetary-gear-set assembly and a rear planetary-gear-set assembly. The front planetary-gear-set assembly and the rear planetary-gear-set assembly are connected in series. The control method includes three modes of transmission: pure hydraulic transmission, hydro-mechanical hybrid transmission, and pure mechanical transmission are implemented through combination and engagement/disengagement of gear-shift components.Type: GrantFiled: October 23, 2019Date of Patent: March 23, 2021Assignee: JIANGSU UNIVERSITYInventors: Zhen Zhu, Yingfeng Cai, Long Chen, Changgao Xia, Xiang Tian, Jiangyi Han, Xiaodong Sun, Dehua Shi, Feng Wang, Chaochun Yuan
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Publication number: 20210071122Abstract: A microfluidic chip for culturing and real-time monitoring of multicellular tissues and use method thereof. The chip comprises a glass substrate layer, and a PDMS microchannel layer located on the glass substrate layer, wherein the glass substrate layer comprises a glass substrate, and a plurality of microelectrodes thereon; the PDMS microchannel comprises a plurality of independent microfluidic channels; the microelectrodes on the glass substrate are in one-to-one correspondence with the microfluidic channels in the PDMS microchannel layer; and the microelectrodes are electrically connected to an external circuit. The use method comprises: cell capture, cell or tissue culture, electrical impedance spectroscopy detection, and tissue release.Type: ApplicationFiled: April 4, 2018Publication date: March 11, 2021Inventors: Zhen ZHU, Qiaodan LI, Dingxin JIN, Feng YU, Yangye GENG
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Patent number: 10751309Abstract: A formulation and method for delivery of bioactive substances when applied to, or within, the skin or other exterior region of a mammal. for example, a patient, includes a vasoactive agent; an osmolyte; and an active ingredient. The formulation is sufficiently hygroscopic so as to create a condition of hypertonicity when absorbed by the skin. When the formulation is applied to the skin, the vasoactive agent can be delivered to the dermis so as to contact the vasculature of a patient.Type: GrantFiled: January 15, 2016Date of Patent: August 25, 2020Assignee: BioChemics, Inc.Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, John J. Masiz
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Publication number: 20200123536Abstract: The present disclosure relates to a circular transposon compound, wherein the circular transposon compound includes a Tn5 transposase and an insert DNA; and the insert DNA contains transposon end sequences, two tag sequences, and a DNA sequence containing an enzymecutting site. The present disclosure further relates to an application of the circular transposon in DNA library construction. In the present disclosure, the method of constructing a DNA library by using the circular transposon compound has simple and convenient operations and high library construction efficiency, wherein the whole process of the library construction can be completed in only 80 minutes, and the required DNA amount is significantly reduced, with 1-50 ng of target DNAs being sufficient for the library construction, thereby promoting the wide application of the next-generation sequencing technology in the life science research and precise medical enterprise, which has great and profound significance.Type: ApplicationFiled: May 16, 2017Publication date: April 23, 2020Applicant: BEIJING TRANSGEN BIOTECH CO., LTD.Inventors: Liang GENG, Zhen ZHU, Wen XIN
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Patent number: 10624867Abstract: The invention provides a topical formulation for treating pain comprising a nonsteroidal anti-inflammatory agent or a Cox-2 inhibitor and a gabapentin family member.Type: GrantFiled: May 9, 2018Date of Patent: April 21, 2020Assignee: Biochemics, Inc.Inventors: Gyula Varadi, Zhen Zhu, John J. Masiz, Stephen G. Carter
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Publication number: 20200101025Abstract: The present invention relates to transdermal delivery systems, methods and kits that include an agent to penetrate the basement membrane, a membrane of the skin previously known to be difficult to penetrate. In particular, the formulation includes a basement membrane disruptor that reversibly denatures the basement membrane of the skin. The formulation of the present invention further includes having at least one penetration agent, at least one vaso-modulator, and at least one active ingredient. In an embodiment, the penetration agent includes a solvent, a lipophilic agent, a hydrophilic agent, wherein the basement membrane disruptor, the vaso-modulator, and the active ingredient pass through the stratum corneum and epidermis. The basement membrane disruptor allows the vaso-modulator and the active ingredient pass through the basement membrane to dermis. The active ingredient, once at the dermis, is delivered locally to the tissue or systemically to the blood stream.Type: ApplicationFiled: September 25, 2019Publication date: April 2, 2020Applicants: BioPhysics Pharma, Inc.Inventors: John J. Masiz, Zhen Zhu
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Patent number: 10537536Abstract: A formulation and method for delivery of bioactive substances when applied to, or within, the skin or other exterior region of a mammal. for example, a patient, includes a vasoactive agent; an osmolyte; and an active ingredient. The formulation is sufficiently hygroscopic so as to create a condition of hypertonicity when absorbed by the skin. When the formulation is applied to the skin, the vasoactive agent can be delivered to the dermis so as to contact the vasculature of a patient.Type: GrantFiled: December 28, 2015Date of Patent: January 21, 2020Assignee: BioChemics, Inc.Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, John J. Masiz