Patents by Inventor Zheng J. Li

Zheng J. Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cristalline 3-{(3R,4R)-4 methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile mono citrate salt
    Patent number: 7803805
    Abstract: This invention relates to novel amorphous and crystallline forms of 3-{(3R,4R)-4-methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3 -oxo-propionitrile mono citrate salt, useful as inhibitors of protein kinases, and to their methods of preparation.
    Type: Grant
    Filed: January 10, 2005
    Date of Patent: September 28, 2010
    Assignee: Pfizer Inc.
    Inventors: Mark E. Flanagan, Zheng J. Li
  • Crystal forms of azithromycin
    Patent number: 7309782
    Abstract: The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: December 18, 2007
    Assignee: Pfizer Inc.
    Inventors: Zheng J. Li, Andrew V. Trask
  • Crystal forms of azithromycin
    Patent number: 7307156
    Abstract: The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections.
    Type: Grant
    Filed: August 27, 2003
    Date of Patent: December 11, 2007
    Assignee: Pfizer Inc.
    Inventors: Zheng J. Li, Andrew V. Trask, Joseph E. Mertz
  • Crystal forms of azithromycin
    Patent number: 7282486
    Abstract: The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections.
    Type: Grant
    Filed: August 27, 2003
    Date of Patent: October 16, 2007
    Assignee: Pfizer Inc
    Inventors: Zheng J. Li, Andrew V. Trask
  • Crystal forms of azithromycin
    Patent number: 7105179
    Abstract: The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: September 12, 2006
    Assignee: Pfizer Inc.
    Inventors: Zheng J. Li, Andrew V. Trask
  • Crystal forms of azithromycin
    Patent number: 7081525
    Abstract: The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: July 25, 2006
    Assignee: Pfizer Inc.
    Inventors: Zheng J. Li, Andrew V. Trask
  • Crystal forms of azithromycin
    Patent number: 7053192
    Abstract: The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: May 30, 2006
    Assignee: Pfizer Inc.
    Inventors: Zheng J. Li, Andrew V. Trask
  • Crystal forms of azithromycin
    Patent number: 6977243
    Abstract: The invention relates to crystal forms of azithromycin, an antibiotic useful in the treatment of infections.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: December 20, 2005
    Assignee: Pfizer Inc.
    Inventors: Zheng J. Li, Andrew V. Trask
  • Crystalline 3-{4-methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile citrate
    Patent number: 6965027
    Abstract: This invention relates to novel amorphous and crystallline forms of 3-{(3R,4R)-4-methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile mono citrate salt, useful as inhibitors of protein kinases, and to their methods of preparation.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: November 15, 2005
    Assignee: Pfizer Inc.
    Inventors: Mark E. Flanagan, Zheng J. Li
  • Stable non-dihydrate azithromycin oral suspensions
    Patent number: 6861413
    Abstract: This invention relates to a powder for oral suspension, and an oral suspension made therefrom, which comprises a n-propanol solvate of non-dihydrate azithromycin and an azithromycin conversion stabilizing excipient, wherein said excipient reduces the conversion of the form of azithromycin, when placed in suspension, to another form of azithromycin. This invention also relates to an oral suspension which comprises a n-propanol solvate of non-dihydrate azithromycin and an aqueous vehicle.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: March 1, 2005
    Assignee: Pfizer Inc.
    Inventors: Zheng J. Li, Andrew V. Trask
  • Salt forms of E-2-methoxy-N-(3-{4-[3 methyl-4-(6-methyl-pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-allyl)-acetamide and method of production
    Patent number: 6844349
    Abstract: The invention relates to succinate and malonate complexes of E-2-Methoxy-N-(3-{4-[3-methyl-4-(6-methyl-pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-allyl)-acetamide having the following formula I: More particular the present invention relates to monosuccinate, hemisuccinate, sesquisuccinate and di-malonate complexes of formula I. The invention also relates to pharmaceutical compositions containing the succinate and malonate complexes of formula I. The invention further relates to methods of treating hyperproliferative diseases, such as cancers, in mammals, especially humans by administering the above complexes and to methods of preparing the above complexes.
    Type: Grant
    Filed: December 10, 2002
    Date of Patent: January 18, 2005
    Assignee: Pfizer Inc
    Inventors: John C. Kath, Daniel T. Richter, Zheng J. Li, Andrew V. Trask
  • Crystal forms of 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl pyridine
    Publication number: 20040266832
    Abstract: The invention concerns crystalline forms of 2-(3-difluromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine, their preparation and use in pharmaceuticals.
    Type: Application
    Filed: June 24, 2004
    Publication date: December 30, 2004
    Inventors: Zheng J. Li, Robert J. Rafka, David H. B. Ripin, Michael J. Castaldi
  • Crystal forms of azithromycin
    Publication number: 20040138149
    Abstract: The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections.
    Type: Application
    Filed: August 27, 2003
    Publication date: July 15, 2004
    Applicant: Pfizer Inc
    Inventors: Zheng J. Li, Andrew V. Trask
  • Stable non-dihydrate azithromycin oral suspensions
    Publication number: 20040121966
    Abstract: This invention relates to a powder for oral suspension, and an oral suspension made therefrom, which comprises a n-propanol solvate of non-dihydrate azithromycin and an azithromycin conversion stabilizing excipient, wherein said excipient reduces the conversion of the form of azithromycin, when placed in suspension, to another form of azithromycin.
    Type: Application
    Filed: July 15, 2003
    Publication date: June 24, 2004
    Applicant: Pfizer Inc.
    Inventors: Zheng J. Li, Andrew V. Trask
  • Crystal forms of 6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-4-(3-ethynyl-phenyl)-1-methyl-1H-quinolin-2-one, 2,3,- dihydroxybutanedioate salts and method of production
    Patent number: 6734308
    Abstract: The invention relates to crystal forms of 6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-4-(3-ethynyl-phenyl)-1-methyl-1H-quinolin-2-one, 2,3-dihydroxy butanedioate salts having the formula shown below: and to pharmaceutical compositions containing the above compound, methods of treating hyperproliferative diseases, such as cancers, in mammals, especially humans by administering the above compound, and to methods of preparing the crystal forms of the above compound and related compounds.
    Type: Grant
    Filed: May 20, 2003
    Date of Patent: May 11, 2004
    Assignee: Pfizer Inc
    Inventors: Joseph P. Lyssikatos, Derek L. Tickner, Linda S. Newton, Zheng J. Li, Clifford N. Meltz
  • Crystal forms of azithromycin
    Publication number: 20040082527
    Abstract: The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections.
    Type: Application
    Filed: August 28, 2003
    Publication date: April 29, 2004
    Applicant: Pfizer Inc
    Inventors: Zheng J. Li, Andrew V. Trask
  • Crystal forms of quinoxaline-2-carboxylic acid [4-carbamoyl-1-(3-fluorobenzyl)-2,7-dihydroxy-7-methyl-octyl]-amide
    Publication number: 20040072834
    Abstract: This invention relates to crystal forms of quinoxaline-2-carboxylic acid [4-carbamoyl-1-(3-fluorobenzyl)-2,7-dihydroxy-7-methyl-octyl]-amide, useful in treating or preventing a disorder or condition by antagonizing the CCR1 receptor, and to their methods of preparation and use.
    Type: Application
    Filed: August 8, 2003
    Publication date: April 15, 2004
    Applicant: Pfizer Inc.
    Inventors: John C. Kath, Zheng J. Li, Zhengong B. Li, Eric McElroy, Clifford N. Meltz, Christopher S. Poss
  • Crystal forms of azithromycin
    Publication number: 20040043944
    Abstract: The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections.
    Type: Application
    Filed: August 27, 2003
    Publication date: March 4, 2004
    Applicant: Pfizer Inc
    Inventors: Zheng J. Li, Andrew V. Trask
  • Crystal forms of azithromycin
    Publication number: 20040043945
    Abstract: The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections.
    Type: Application
    Filed: August 28, 2003
    Publication date: March 4, 2004
    Applicant: Pfizer Inc
    Inventors: Zheng J. Li, Andrew V. Trask
  • Crystal forms of 6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-4-(3-ethynyl-phenyl)-1-methyl-1H-quinolin-2-one, 2,3,- dihydroxybutanedioate salts and method of production
    Publication number: 20030212103
    Abstract: The invention relates to crystal forms of 6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-4-(3-ethynyl-phenyl)-1-methyl-1H-quinolin-2-one, 2,3-dihydroxy butanedioate salts having the formula shown below: 1
    Type: Application
    Filed: May 20, 2003
    Publication date: November 13, 2003
    Applicant: Pfizer Inc.
    Inventors: Joseph P. Lyssikatos, Derek L. Tickner, Linda S. Newton, Zheng J. Li, Clifford N. Meltz