Patents by Inventor Zheng-Jun Li

Zheng-Jun Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microbial production of renewable glycolate
    Patent number: 10294481
    Abstract: Some aspects provide engineered microbes for glycolate production. Methods for microbe engineering and culturing are also provided herein. Such engineered microbes exhibit greatly enhanced capabilities for glycolate production.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: May 21, 2019
    Assignee: Massachusetts Institute of Technology
    Inventors: Gregory Stephanopoulos, Zheng-Jun Li, Brian Pereira
  • MICROBIAL PRODUCTION OF RENEWABLE GLYCOLATE
    Publication number: 20170121717
    Abstract: Some aspects provide engineered microbes for glycolate production. Methods for microbe engineering and culturing are also provided herein. Such engineered microbes exhibit greatly enhanced capabilities for glycolate production.
    Type: Application
    Filed: September 30, 2016
    Publication date: May 4, 2017
    Applicant: Massachusetts Institute of Technology
    Inventors: GREGORY STEPHANOPOULOS, Zheng-Jun Li, Brian Pereira
  • Recombinant hosts and methods for manufacturing polyhydroxyalkanoate
    Patent number: 8546125
    Abstract: Known attempts using engineered bacteria to produce P(3HB-co-4HB) with carbon sources that are structurally unrelated to 4-hydroxybutyrate resulted in relatively low 4HB monomer content of 1.5 to 5 mol %. The current invention provides recombinant hosts for producing P(3HB-co-4HB) wherein the plasmid including succinate semialdehyde dehydrogenase gene (sucD gene) and 4-hydroxybutyrate dehydrogenase gene (4hbD gene) further includes pyruvate decarboxylase promoter (Ppdc). It was found that the 4HB monomer content in P(3HB-co-4HB) is significantly enhanced to be over 20 mol %, in the range of 8.8 to 23 mol %.
    Type: Grant
    Filed: February 21, 2011
    Date of Patent: October 1, 2013
    Assignee: Tianjin Greenbio Material Co., Ltd.
    Inventors: Guo-Qiang Chen, Zheng-Jun Li, Zhen-Yu Shi, Ying-Ying Guo, Jia Jian, Qiong Wu
  • RECOMBINANT HOSTS AND METHODS FOR MANUFACTURING POLYHYDROXYALKANOATE
    Publication number: 20120214213
    Abstract: Known attempts using engineered bacteria to produce P(3HB-co-4HB) with carbon sources that are structurally unrelated to 4-hydroxybutyrate resulted in relatively low 4HB monomer content of 1.5 to 5 mol %. The current invention provides recombinant hosts for producing P(3HB-co-4HB) wherein the plasmid including succinate semialdehyde dehydrogenase gene (sucD gene) and 4-hydroxybutyrate dehydrogenase gene (4hbD gene) further includes pyruvate decarboxylase promoter (Ppdc). It was found that the 4HB monomer content in P(3HB-co-4HB) is significantly enhanced to be over 20 mol %, in the range of 8.8 to 23 mol %.
    Type: Application
    Filed: February 21, 2011
    Publication date: August 23, 2012
    Applicant: TIANJIN GREENBIO MATERIAL CO., LTD.
    Inventors: Guo-Qiang Chen, Zheng-Jun Li, Ying-Ying Guo, Wei-Chuan Lu, Zi-Zhen Zhou