Abstract: The present disclosure provides an integration method for multiple centralized units, an integration device for multiple centralized units, and an integration system for multiple centralized units. The integration system for multiple centralized units includes a centralized unit center, the centralized unit center is configured to integrate multiple logical centralized units, the multiple logical centralized units share one or more function modules at corresponding levels according to a preset service requirement, and the function modules at the corresponding levels are configured to provide function services at the corresponding levels for the logical centralized units.

Abstract: An envelope tracking power amplifier module and an envelope tracking method are provided. The envelope tracking power amplifier module includes a power amplifier and a linear amplifier coupled to the power amplifier and configured to receive and amplify an envelope signal and provide the amplified envelope signal to the power amplifier. The power amplifier is configured to receive and amplify a signal according to the amplified envelope signal. The envelope tracking method includes: providing a signal to the power amplifier; deriving an envelope phase of the signal, the envelope phase corresponding to an output power of the power amplifier; providing an envelope signal including the envelope phase to the envelope tracking module; the envelope tracking module providing the amplified envelope signal to the power amplifier; and the power amplifier amplifying the signal according to the amplified envelope signal and outputting the amplified signal at the output power.

Abstract: The disclosure discloses a recombinant Bacillus subtilis engineered bacterium capable of efficiently expressing keratinase, and belongs to the technical fields of genetic engineering and fermentation engineering. The disclosure successfully constructs a genetically engineered bacterium B. subtilis WB600-pP43NMK-ker capable of efficiently expressing keratinase by using a keratinase gene from Bacillus licheniformis (BBE11-1) as a target gene, pP43NMK as an expression vector and B. subtilis WB600 as an expression host; and meanwhile, the disclosure conducts in-depth research on fermentation media and fermentation conditions when the engineered bacteria are configured as a production strain to produce keratinase to obtain a fermentation medium capable of increasing a yield of keratinase and an optimum process for fermentation production of keratinase.

Abstract: A non-common-ground bandpass filter circuit with electrostatic discharge (ESD) protection is disclosed. The non-common-ground bandpass filter circuit with ESD protection includes a non-common-ground plane, a dielectric substrate and a conductor. The conductor is disposed above the non-common-ground plane. The dielectric substrate is disposed between the conductor and the non-common-ground plane. The non-common-ground plane at least has a first ground region and a second ground region separated and insulated from each other. The first ground region corresponds to a first terminal of the conductor and the second ground region corresponds to a second terminal of the conductor. When an ESD event occurs on one of the first ground region and the second ground region, the other of the first ground region and the second ground region will not be damaged by the ESD event. The non-common-ground bandpass filter circuit also provides surge protection.

Abstract: A positioning and tracking system is disclosed. The positioning and tracking system includes positioning sensors disposed in a space, wherein the positioning sensors are all movable and all have functions of sensing distance, angle and time, and the positioning sensors communicate with each other to sense relative distances, relative angles and relative times between every two positioning sensors of the positioning sensors. when at least one of the positioning sensors moves in the space, the positioning sensors re-communicate with each other to instantly update the relative distances, the relative angles and the relative times between every two positioning sensors of the positioning sensors.

Abstract: An envelope tracking power amplifier module and an envelope tracking method are provided. The envelope tracking power amplifier module includes a power amplifier and a linear amplifier coupled to the power amplifier and configured to receive and amplify an envelope signal and provide the amplified envelope signal to the power amplifier. The power amplifier is configured to receive and amplify a signal according to the amplified envelope signal. The envelope tracking method includes: providing a signal to the power amplifier; deriving an envelope phase of the signal, the envelope phase corresponding to an output power of the power amplifier; providing an envelope signal including the envelope phase to the envelope tracking module; the envelope tracking module providing the amplified envelope signal to the power amplifier; and the power amplifier amplifying the signal according to the amplified envelope signal and outputting the amplified signal at the output power.

Abstract: The present invention provides an antenna structure, an antenna device and a wireless localization method. The antenna structure includes a first radiation unit including a plurality of first connecting portions and a plurality of first annular radiation portions, a second radiation unit including a plurality of second connecting portions and a plurality of second annular radiation portions, a first conductive wire and a plurality of second conductive wires. A first end of each first annular radiation portion is connected to the first connecting portion, and the second end thereof extends towards the first end of the adjacent first annular radiation portion. A first end of each second annular radiation portion is connected to the second connecting portion, and the second end thereof extends towards the first end of the adjacent second annular radiation portion.

Abstract: A compound for treating a protein kinase-related disease or disorder having a structure of formula (I) wherein L is NR8 or O; R1, R2, R3, R4, R5, R6 and R7 are defined herein. Compounds of formula (I) are useful for inhibition of protein kinases. Methods of using compounds of formula (I), stereoisomers, tautomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

Abstract: A compound, capable of inhibiting kinases, for the treatments of diseases or disorders mediated by such kinases, has a structure of formula (I): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt thereof. The compound can be used in the treatments of diseases or conditions mediated by CSF-1R, c-KIT, FLT3, or PDGFR kinases. Such diseases or conditions may include cancers, autoimmune diseases, and bone resorptive diseases.

Abstract: The present invention provides an antenna structure, an antenna device and a wireless localization method. The antenna structure includes a first radiation unit including a plurality of first connecting portions and a plurality of first annular radiation portions, a second radiation unit including a plurality of second connecting portions and a plurality of second annular radiation portions, a first conductive wire and a plurality of second conductive wires. A first end of each first annular radiation portion is connected to the first connecting portion, and the second end thereof extends towards the first end of the adjacent first annular radiation portion. A first end of each second annular radiation portion is connected to the second connecting portion, and the second end thereof extends towards the first end of the adjacent second annular radiation portion.

Abstract: A regioselective one-step process for the synthesis of 2-hydroxyquinoxaline of Formula (1) or tautomers thereof: comprising reacting 1,2-phenylenediamine of Formula (2): with an excess amount of glyoxylic acid, glyoxylic acid monohydrate, or a 2,2-dialkoxyacetic acid of Formula (3): at a low temperature; wherein R1 and R2 are as defined in the specification.

Abstract: A compound, capable of inhibiting kinases, for the treatments of diseases or disorders mediated by such kinases, has a structure of formula (I): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt thereof. The compound can be used in the treatments of diseases or conditions mediated by CSF-1R, c-KIT, FLT3, or PDGFR kinases. Such diseases or conditions may include cancers, autoimmune diseases, and bone resorptive diseases.

Abstract: A compound for treating a protein kinase-related disease or disorder having a structure of formula (I) wherein L is NR8 or O; R1, R2, R3, R4, R5, R6 and R7 are defined herein. Compounds of formula (I) are useful for inhibition of protein kinases.

Abstract: A system and a method for optimizing fundamental frequency modulation in a cascaded multilevel inverter (CMI) are provided. The CMI includes at least a first H-bridge module and a second H-bridge module connected in series with the first H-bridge module. The first H-bridge module is operated according to a first duty cycle and the second H-bridge module is operated according to a second duty cycle. The first duty cycle is greater than the second duty cycle. The first and second H-bridge modules are controlled utilizing fundamental frequency modulation. A portion of the first duty cycle is transferred to the second duty cycle thereby optimizing fundamental frequency modulation by at least improving power sharing between the first and second H-bridge modules and improving equalization of DC capacitor currents and voltage ripples while maintaining the same fundamental modulation to the output voltage waveform.

Abstract: A system and a method for optimizing fundamental frequency modulation in a cascaded multilevel inverter (CMI) are provided. The CMI includes at least a first H-bridge module and a second H-bridge module connected in series with the first H-bridge module. The first H-bridge module is operated according to a first duty cycle and the second H-bridge module is operated according to a second duty cycle. The first duty cycle is greater than the second duty cycle. The first and second H-bridge modules are controlled utilizing fundamental frequency modulation. A portion of the first duty cycle is transferred to the second duty cycle thereby optimizing fundamental frequency modulation by at least improving power sharing between the first and second H-bridge modules and improving equalization of DC capacitor currents and voltage ripples while maintaining the same fundamental modulation to the output voltage waveform.

Abstract: An improved gate drive circuit is provided for a power device, such as a transistor. The gate driver circuit may include: a current control circuit; a first secondary current source that is used to control the switching transient during turn off of the power transistor and a second secondary current source that is used to control the switching transient during turn on of the power transistor. In operation, the current control circuit operates, during turn on of the power transistor, to source a gate drive current to a control node of the power transistor and, during turn off of the power transistor, to sink a gate drive current from the control node of the power transistor. The first and second secondary current sources adjust the gate drive current to control the voltage or current rate of change and thereby the overshoot during the switching transient.

Abstract: A compound for treating a protein kinase-related disease or disorder having a structure of formula (I) wherein G is a heteroaryl, heterocyclic or alkyne; X is N or CH; L1 is —N(R7)—, —O—, —C(S)—, —C(O)—, or —S—; L2 is —N(R8)— or —O—; R1 and R2 are independently hydrogen, halogen, hydroxyl, amino, cyano, nitro, carboxy, C1-C4 alkoxy, C1-C4 alkoxy C1-C4 alkoxy, N,N—(C1-C4 dialkyl)amino C1-C4 alkoxy, N—(C1-C4 alkyl)amino C1-C4 alkoxy, C1-C4 alkanoyl, C1-C4 alkanoyloxy, N—(C1-C4 alkyl)amino, N,N—(C1-C4 dialkyl)amino, C1-C4 alkanoyl amino, or heterocyclyl, wherein C1-C4 alkyl is optionally substituted with one or more substituents selected from fluorine and chlorine; R3, R4 and R5 are independently hydrogen, fluorine or chlorine; R6 is C1-C4 alkyl or aryl, which is optionally substituted with one or more substituents selected from halogen, hydroxyl, amino, cyano, nitro; or R6 and R8 form a 5-6 membered cyclyl or heterocyclyl.

Abstract: A power control device includes a first terminal, a second terminal connected to a transmission line, a first cascade multilevel inverter (CMI) and a second CMI. The first CMI is connected to the second terminal. The second CMI connected in series between the first terminal and the second terminal.

Abstract: A compound for treating a protein kinase-related disease or disorder having a structure of formula (I) wherein G is a heteroaryl, heterocyclic or alkyne; X is N or CH; L1 is —N(R7)—, —O—, —C(S)—, —C(O)—, or —S—; L2 is —N(R8)— or —O—; R1 and R2 are independently hydrogen, halogen, hydroxyl, amino, cyano, nitro, carboxy, C1-C4 alkoxy, C1-C4 alkoxy C1-C4 alkoxy, N,N—(C1-C4 dialkyl)amino C1-C4 alkoxy, N—(C1-C4 alkyl)amino C1-C4 alkoxy, C1-C4 alkanoyl, C1-C4 alkanoyloxy, N—(C1-C4 alkyl)amino, N,N—(C1-C4 dialkyl)amino, C1-C4 alkanoyl amino, or heterocyclyl, wherein C1-C4 alkyl is optionally substituted with one or more substituents selected from fluorine and chlorine; R3, R4 and R5 are independently hydrogen, fluorine or chlorine; R6 is C1-C4 alkyl or aryl, which is optionally substituted with one or more substituents selected from halogen, hydroxyl, amino, cyano, nitro; or R6 and R8 form a 5-6 membered cyclyl or heterocyclyl.

Abstract: A power control device includes a first terminal, a second terminal connected to a transmission line, a first cascade multilevel inverter (CMI) and a second CMI. The first CMI is connected to the second terminal. The second CMI connected in series between the first terminal and the second terminal.