Patents by Inventor Zheng-Yu Yang

Zheng-Yu Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Flavone acetic acid analogs and methods of use thereof
    Patent number: 6916831
    Abstract: Compounds are described having a structure according to Formula I or Formula II: wherein: X is selected from the group consisting of O, NH, and S; Y is selected from the group consisting of O and S; m is from 1 to 3; n is from 1 to 5; R1 and R3 are each independently selected from the group consisting of H, hydroxy, lower alky, lower alkoxy, halo, amino, aminoalkyl, nitro, heteroaryl, —OC(?O)R6, —O(C?O)OR6; and —O(C?O)N(R6)2; and R2 is side chain such as an acetic acid side chain, where p is O to 4, R5 is hydroxy, alkoxy or amino, and R6 is H or lower alkyl, or a pharmaceutically acceptable salt thereof. The compounds are useful for the treatment of cancer.
    Type: Grant
    Filed: February 24, 2003
    Date of Patent: July 12, 2005
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Kuo-Hsiung Lee, Yi Xia, Zheng-Yu Yang, Kenneth F. Bastow, Sheng-Chu Kuo
  • Flavone acetic acid analogs and methods of use thereof
    Publication number: 20040167151
    Abstract: Compounds are described having a structure according to Formula I or Formula II: 1
    Type: Application
    Filed: February 24, 2003
    Publication date: August 26, 2004
    Inventors: Kuo-Hsiung Lee, Yi Xia, Zheng-Yu Yang, Kenneth F. Bastow, Sheng-Chu Kuo
  • Fluorinated quinolones as antimitotic and antitumor agents
    Patent number: 6569870
    Abstract: The present invention provides fluorinated quinolones which are fluorinated on the phenyl group thereof, along with pharmaceutical formulations containing the same, methods of treating tumors or cancer by the administration of such compounds, and methods of inhibiting cellular mitosis by the administration of such compounds.
    Type: Grant
    Filed: September 25, 2000
    Date of Patent: May 27, 2003
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Kuo-Hsiung Lee, Yi Xia, Zheng-Yu Yang, Sheno-Chu Kuo