Patents by Inventor Zheng Z. Wu
Zheng Z. Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10376473Abstract: A stable transdermal adhesive composition comprising: an adhesive comprising a washed polymerization reaction product of at least two ethylenically unsaturated monomers; and at least one pharmaceutically active compound which is susceptible to oxidative degradation; wherein the at least two ethylenically unsaturated monomers, if present in the adhesive as unreacted monomers, are present at a level of less than 200 ppm of total unreacted monomer, based upon the total weight of the adhesive, methods of making the composition, a transdermal drug delivery device using the composition, methods of making the device, and methods of delivery the pharmaceutically active compound are provided.Type: GrantFiled: July 23, 2018Date of Patent: August 13, 2019Assignee: 3M Innovative Properties CompanyInventors: James P. DiZio, Elizabeth E. Johnson, Zheng Z. Wu, Amy Preszler Prince
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Publication number: 20180325838Abstract: A stable transdermal adhesive composition comprising: an adhesive comprising a washed polymerization reaction product of at least two ethylenically unsaturated monomers; and at least one pharmaceutically active compound which is susceptible to oxidative degradation; wherein the at least two ethylenically unsaturated monomers, if present in the adhesive as unreacted monomers, are present at a level of less than 200 ppm of total unreacted monomer, based upon the total weight of the adhesive, methods of making the composition, a transdermal drug delivery device using the composition, methods of making the device, and methods of delivery the pharmaceutically active compound are provided.Type: ApplicationFiled: July 23, 2018Publication date: November 15, 2018Inventors: James P. DiZIO, Elizabeth E. JOHNSON, Zheng Z. WU, Amy PRESZLER PRINCE
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Patent number: 10034840Abstract: A stable transdermal adhesive composition comprising: an adhesive comprising a washed polymerization reaction product of at least two ethylenically unsaturated monomers; and at least one pharmaceutically active compound which is susceptible to oxidative degradation; wherein the at least two ethylenically unsaturated monomers, if present in the adhesive as unreacted monomers, are present at a level of less than 200 ppm of total unreacted monomer, based upon the total weight of the adhesive, methods of making the composition, a transdermal drug delivery device using the composition, methods of making the device, and methods of delivery the pharmaceutically active compound are provided.Type: GrantFiled: May 31, 2016Date of Patent: July 31, 2018Assignee: 3M Innovative Properties CompanyInventors: James P. Dizio, Elizabeth E. Johnson, Zheng Z. Wu, Amy Preszler Prince
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Publication number: 20160271074Abstract: A stable transdermal adhesive composition comprising: an adhesive comprising a washed polymerization reaction product of at least two ethylenically unsaturated monomers; and at least one pharmaceutically active compound which is susceptible to oxidative degradation; wherein the at least two ethylenically unsaturated monomers, if present in the adhesive as unreacted monomers, are present at a level of less than 200 ppm of total unreacted monomer, based upon the total weight of the adhesive, methods of making the composition, a transdermal drug delivery device using the composition, methods of making the device, and methods of delivery the pharmaceutically active compound are provided.Type: ApplicationFiled: May 31, 2016Publication date: September 22, 2016Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: JAMES P. DIZIO, ELIZABETH E. JOHNSON, ZHENG Z. WU, AMY PRESZLER PRINCE
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Publication number: 20040033201Abstract: A medicinal aerosol steroid solution formulation product with enhanced chemical stability. The steroid is a 20-ketosteroid having an OH group at the C-17 or C-21 position and the aerosol container has a non-metal interior surface which has been found to reduce chemical degradation of such steroids.Type: ApplicationFiled: July 30, 2003Publication date: February 19, 2004Applicant: 3M Innovative Properties CompanyInventors: Zheng Z. Wu, Nayna Govind, Peter R. Johnson
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Patent number: 6610273Abstract: A medicinal aerosol steroid solution formulation product with enhanced chemical stability. The steroid is a 20-ketosteroid having an OH group at the C-17 or C-21 position and the aerosol container has a non-metal interior surface which has been found to reduce chemical degradation of such steroids.Type: GrantFiled: October 4, 2001Date of Patent: August 26, 2003Assignee: 3M Innovative Properties CompanyInventors: Zheng Z. Wu, Nayna Govind, Peter R. Johnson
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Publication number: 20020071810Abstract: A medicinal aerosol steroid solution formulation product with enhanced chemical stability. The steroid is a 20-ketosteroid having an OH group at the C-17 or C-21 position and the aerosol container has a non-metal interior surface which has been found to reduce chemical degradation of such steroids.Type: ApplicationFiled: October 4, 2001Publication date: June 13, 2002Applicant: 3M Innovative Properties CompanyInventors: Zheng Z. Wu, Nayna Govind, Peter R. Johnson
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Patent number: 6315985Abstract: A medicinal aerosol steroid solution formulation product with enhanced chemical stability. The steroid is a 20-ketosteroid having an OH group at the C-17 or C-21 position and the aerosol container has a non-metal interior surface which has been found to reduce chemical degradation of such steroids.Type: GrantFiled: June 13, 2000Date of Patent: November 13, 2001Assignee: 3M Innovative Properties CompanyInventors: Zheng Z. Wu, Nayna Govind, Peter R. Johnson
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Patent number: 6280919Abstract: The invention provides a photographic element comprising a light-sensitive silver halide emulsion layer having associated therewith a coupler based on a 1-aryl-3-arylpyrazol-5-one ring and represented by formula I: wherein the substituents are as described in the specification.Type: GrantFiled: December 30, 1998Date of Patent: August 28, 2001Assignee: Eastman Kodak CompanyInventors: Wojciech K. Slusarek, Jerrold N. Poslusny, Zheng Z. Wu
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Patent number: 6150078Abstract: The invention provides a photographic element comprising a light-sensitive silver halide emulsion layer having associated therewith an 1-arylpyrazol-5-one coupler bearing a 4-aryloxy coupling-off group containing a group capable of releasing a photographically useful group (PUG) wherein:(1) the 1-arylpyrazol-5-one ring contains a 3-aryl substituent which in turn contains substituents for which the sum of the Hammett's .sigma. constant values is at least 0, provide that two or more such substituents may join to form one or more additional rings; and(2) the 4-aryloxy coupling-off group:(a) contains ring substituents selected so that the sum of the Hammett's sigma constant values for all substituents on the aryloxy ring is at least 0.Type: GrantFiled: December 30, 1998Date of Patent: November 21, 2000Assignee: Eastman Kodak CompanyInventors: Wojciech K. Slusarek, Jerrold N. Poslusny, Zheng Z. Wu, Xiqiang Yang
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Patent number: 6132944Abstract: Disclosed is a photographic element containing a light sensitive silver halide emulsion layer having associated therewith a coupler represented by Formula I: ##STR1## wherein COUP is a coupler parent group capable of reacting with an oxidized developer to form a first dye and is bonded at a coupling position to the group ##STR2## wherein X is a or NSO.sub.2 R; R is an alkyl or aryl group; and DYE is a releasable second dye that is after release the same color as the first dye and is linked to OC.dbd.X by a moiety of the DYE having Formula (IA): ##STR3## wherein R.sup.2 is a substituent; provided there is contained in the coupler of Formula I at least one group of Formula IB:--L.sub.m --Sol IBwherein L is a divalent linking group and m is 0 or 1; and Sol is a group containing an acidic hydrogen selected from the group consisting of --ArOH, --NHSO.sub.2 R.sup.1 and --SO.sub.2 NHR.sup.1, in which AR is an aromatic group and each R.sup.Type: GrantFiled: November 4, 1999Date of Patent: October 17, 2000Assignee: Eastman Kodak CompanyInventors: Jared B. Mooberry, Steven M. Bonser, Kevin P. Dockery, David Hoke, Chang-Kyu Kim, James J. Seifert, David T. Southby, Zheng Z. Wu
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Patent number: 5576167Abstract: A photographic element comprises a light-sensitive silver halide emulsion layer having associated therewith a coupler based on a 1-aryl-2-pyrazolin-5-one ring and represented by formula I: ##STR1## wherein: Ar.sup.1 and Ar.sup.2 are each independently aryl groups comprising a carboaromatic or heteroaromatic ring;X, Y, and Z are bonded to a carbon atom alpha to the 3-position and are independently selected from the group consisting of hydrogen and substituent groups such that the sum of the Taft .sigma.* values for X, Y, and Z is at least 1.5;R represents n independently selected substituent groups bonded to the Ar.sup.2 ring, provided that the sum of the appropriate Hammett .sigma. constants for all R substituent groups is at least 0.3, and provided further that two of X, Y, and Z may join to form a ring; andn is 0 to 5;provided that R may not be a nitro group ortho to the oxygen atom bonding Ar.sup.2 to the 1-aryl-2-pyrazolin-5-one ring.Type: GrantFiled: December 30, 1994Date of Patent: November 19, 1996Assignee: Eastman Kodak CompanyInventors: Jerrold N. Poslusny, Lawrence G. Anderson, Jared B. Mooberry, Zheng Z. Wu
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Patent number: 5457004Abstract: The invention provides a photographic element comprising a substrate bearing a photographic silver halide emulsion layer having associated therewith a high dye-yield coupler having the formula: ##STR1## wherein: COUP is a photographic coupler residue capable of coupling with oxidized color developer to form a first dye;T is a timing group;m is an integer from 0 to 2;L is a linking group selected from the group consisting of --OC(.dbd.O)--, --OC(.dbd.S)--, --SC(.dbd.O)--, --SC(.dbd.S)--, and --OC(.dbd.NSO.sub.2 R) where R is substituted or unsubstituted alkyl or aryl; andDYE is a releasable second dye or dye precursor having a particular formula including a methine dye chromophore.Type: GrantFiled: May 27, 1994Date of Patent: October 10, 1995Assignee: Eastman Kodak CompanyInventors: Jared B. Mooberry, James J. Seifert, David Hoke, Zheng Z. Wu, David T. Southby, Frank D. Coms
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Patent number: 5447819Abstract: The invention provides a photographic element comprising a support bearing a photographic silver halide emulsion layer having associated therewith a high dye-yield coupler having the formula:COUP--(T).sub.m --L--DYEwhere COUP is the parent group of the coupler capable of reacting at the coupling position with oxidized color developer to form a first dye, T is one or more timing groups with m=1 or 2, L is a linking group selected from the group consisting of --OC(O)--, --OC(S)--, --SC(O)--, --SC(S)--, or --OC(.dbd.N SO.sub.2 R)--, where R is substituted or unsubstituted alkyl or aryl, and DYE is a second dye or precursor thereof, wherein there is present at least one T group that contains a substituent having the formula:--(LINK).sub.p --A--B--(C--D).sub.nwherein:LINK is an alkylene group capable of linking the above group to the group T, where p=0 or 1;A is a member selected from the group consisting of --NHCO--, --N(R')C(O)N(R--)--, --CONH--, --NR'SO.sub.2 --, --SO.sub.2 NR'--, and --OPO.sub.Type: GrantFiled: May 27, 1994Date of Patent: September 5, 1995Assignee: Eastman Kodak CompanyInventors: Jared B. Mooberry, James J. Seifert, David Hoke, Zheng Z. Wu, David T. Southby, Frank D. Coms