Abstract: A system described herein may provide a technique for performing carrier aggregation in a wireless telecommunications network in a manner that accounts for (a) diverse licenses for different carriers across different regions, (b) network considerations in minimizing the number of times carrier aggregation is performed, and (c) user equipment (“UE”) considerations in maximizing battery life by utilizing only the carriers that are necessary to utilize. A smallest carrier (or group of carriers) may be identified as a default carriers, and other carriers or groups of carriers may be ranked in descending order, according to size. The ranked list may be iteratively used when performing carrier aggregation, in which the largest available carrier (or group of carriers) from the list may be used for carrier aggregation.

Abstract: An energy storage system that comprises an energy reservoir and a system controller. The energy reservoir is charged by DC energy from a DC energy source while discharging DC energy to a DC/AC converter. A system controller regulates the DC energy discharged from the energy reservoir to the DC/AC converter to nearly balance the amount of DC energy charged into the energy reservoir. Because this charging and discharging is nearly balanced, the size of the energy reservoir can be made quite small relative to the amount of charging and discharging. This is advantageous where the flow of charge and discharge is high, as might be the case if the energy reservoir receives charge from all or a substantial portion of a power station, such as a solar power station. With such a controller, the use of an energy reservoir becomes technically feasible even with such large current flows.

Abstract: The present invention relates to a host cell which is capable of producing a dicarboxylic acid and which comprises at least one genetic modification in its genome resulting in the deficiency of at least one enzymatic step catalysing the oxidation of a cofactor. The invention also relates to a process for producing a dicarboxylic acid, which method comprises fermenting such a host cell in a suitable fermentation medium and producing the dicarboxylic acid.

Abstract: Disclosed in the present application are a radio link monitoring method and apparatus, the method comprising: when a UE performs radio link monitoring, the UE monitors a downlink signal of a primary serving cell to obtain monitoring results; and the UE compares the monitoring results with an required synchronization threshold to determine whether the UE is in a synchronized state; the synchronization threshold is determined on the basis of preset parameters. The present invention solves the problems in the prior art of the complexity of defining RLM performance requirements, and being unable to provide the needed flexibility for supporting different specific systems by means of adjusting thresholds.

Abstract: A method of indicating a synchronization signal block (SSB), a method of determining SSB, an apparatus of indicating an SSB, an apparatus of determining an SSB, a base station, user equipment (UE) and a computer readable storage medium are provided. The method of indicating an SSB includes: determining a target pattern from a plurality of patterns and acquiring serial number information corresponding to the SSB based on the target pattern; determining, according to the serial number information corresponding to the SSB, position indication information in an indication signaling for indicating a corresponding position of the SSB; and transmitting the position indication information to UE.

Abstract: A random access method, a base station and a User Equipment (UE) are provided. A random access method applied to a base station side includes: receiving, by using a pre-configured first SubCarrier Spacing (SCS), a first random access preamble message transmitted by a UE when the base station instructs the UE to perform an initial access according to a contention-based random access mechanism; transmitting, by using a predetermined second SCS or a third SCS configured by a network, a first Random Access Response (RAR) message to the UE; receiving, by using a predetermined fourth SCS or a fifth SCS configured by the network, a first scheduling transmission message transmitted by the UE; and transmitting, by using a predetermined sixth SCS or a seventh SCS configured by the network, a first collision resolution message to the UE, to complete the initial access.

Abstract: A system described herein may provide a technique for performing carrier aggregation in a wireless telecommunications network in a manner that accounts for (a) diverse licenses for different carriers across different regions, (b) network considerations in minimizing the number of times carrier aggregation is performed, and (c) user equipment (“UE”) considerations in maximizing battery life by utilizing only the carriers that are necessary to utilize. A smallest carrier (or group of carriers) may be identified as a default carriers, and other carriers or groups of carriers may be ranked in descending order, according to size. The ranked list may be iteratively used when performing carrier aggregation, in which the largest available carrier (or group of carriers) from the list may be used for carrier aggregation.

Abstract: A method, a device, and a non-transitory storage medium are described in which a network slice-based admission and congestion control service is provided. The congestion control service monitors for congestion in a network slice. When congestion is detected, the congestion control service may adjust an allotment of a resource of a network device or the resource of the network slice from end-to-end. When neither of these adjustments can be made, the congestion control service may use a network slice-based access control barring.

Abstract: A method, a device, and a non-transitory storage medium are described in which a network slice-based admission and congestion control service is provided. The congestion control service monitors for congestion in a network slice. When congestion is detected, the congestion control service may adjust an allotment of a resource of a network device or the resource of the network slice from end-to-end. When neither of these adjustments can be made, the congestion control service may use a network slice-based access control barring.

Abstract: A data transmission method, apparatus and system, the method comprising: for an initial access uplink data transmission, determining a modulation and coding scheme for uplink data according to protocol specification and/or base station broadcast information; using the determined modulation and coding scheme to perform modulation and coding on the uplink data, and sending a preamble and the modulated and coded uplink data. In the present invention, the modulation and coding scheme for the uplink data for the initial access uplink data transmission is determined according to the protocol specification and/or base station broadcast information, and the modulation and coding is thereby performed on the uplink data.

Abstract: Disclosed are a data transmission method, device, and system. The method comprises: for the transmission of random access uplink data, according to the correspondence between preambles and data resources as described by a protocol, determining the data resource corresponding to the preamble in the uplink data transmission, different preambles corresponding to different data resources; transmitting the preamble and the uplink data that uses the determined data resource. In the embodiments of the present invention, a protocol describes the correspondence between preambles and data resources. For the transmission of random access uplink data, the data resource corresponding to the preamble in the uplink data transmission can be determined, and different preambles correspond to different data resources. Thus it can be ensured that different users use different data resources to bear uplink data, thereby enabling the data portion multiplexing for multiple users.

Abstract: A system described herein may provide a technique for performing carrier aggregation in a wireless telecommunications network in a manner that accounts for (a) diverse licenses for different carriers across different regions, (b) network considerations in minimizing the number of times carrier aggregation is performed, and (c) user equipment (“UE”) considerations in maximizing battery life by utilizing only the carriers that are necessary to utilize. A smallest carrier (or group of carriers) may be identified as a default carriers, and other carriers or groups of carriers may be ranked in descending order, according to size. The ranked list may be iteratively used when performing carrier aggregation, in which the largest available carrier (or group of carriers) from the list may be used for carrier aggregation.

Abstract: A method for transmitting a synchronization sequence, and a method and a device for synchronization detection are provided, the method for transmitting the synchronization sequence including: setting a target synchronization sequence with good autocorrelation characteristic, where at least one segment of sequence truncated in a time domain or a frequency domain of the target synchronization sequence is a sub-synchronization sequence, and the sub-synchronization sequence has good autocorrelation characteristic and the sub-synchronization sequences have good cross-correlation between each other; and transmitting the target synchronization sequence to a user equipment.

Abstract: An uplink scheduling-free transmission method and an uplink scheduling-free transmission device are provided. The uplink scheduling-free transmission method includes: dividing, by a base station, MA resources into groups of MA resources, and configuring, by the base station, the groups of MA resources to obtain at least two groups of MA resource pools, wherein at least parts of respective MA resources in the at least two groups of MA resource pools are different from each other; and notifying, by the base station, a UE of the at least two groups of MA resource pools, to enable the UE to select an MA resource pool from the at least two groups of MA resource pools, wherein the selected MA resource pool is to be used by the UE.

Abstract: A method, a device, and a non-transitory storage medium are described in which a network slice-based admission and congestion control service is provided. The congestion control service monitors for congestion in a network slice. When congestion is detected, the congestion control service may adjust an allotment of a resource of a network device or the resource of the network slice from end-to-end. When neither of these adjustments can be made, the congestion control service may use a network slice-based access control barring.

Abstract: The present application provides a compound of formula I, which is a EGFR and ALK dual inhibitor and can be used alone or in combination with other therapeutic agents to treat diseases such as non-small cell lung cancer. The compounds of the present application are useful in the treatment of diseases carrying the EGFR wild-type gene, or carrying the EGFR T790M mutant gene and/or the EGFR L858R mutant gene and/or the EGFR delE746_A750 mutant gene, or in the treatment of diseases carrying the ALK wild-type gene, ALK F1174L mutant gene and/or ALK F1196M gene and/or EML4-ALK mutant gene and/or NPM-ALK mutant gene, and can be used in the first-line treatment of anaplastic lymphoma kinase (ALK) positive late-stage non-small cell Lung cancer.

Abstract: A microfluidic exosome profiling platform integrating exosome isolation and targeted proteomic analysis is disclosed. This platform is capable of quantitative exosomal biomarker profiling directly from plasma samples with markedly enhanced sensitivity and specificity. Identification of distinct subpopulation of patient-derived exosomes is demonstrated by probing surface proteins and multiparameter analyzes of intravesicular biomarkers in the selected subpopulation. The expression of IGF-1R and its phosphorylation level in non-small cell lung cancer (NSCLC) patient plasma is assessed as a non-invasive alternative to the conventional biopsy and immunohistochemistry. Detection of ovarian cancer also is assessed. The microfluidic chip, which may be fabricated of a glass substrate and a layer of poly(dimethylsiloxane), includes a serpentine microchannel to mix a fluid and a microchamber for the collection and detection of exosomes.

Abstract: Provided are a quality control method for banknote identification and a quality control system for banknote identification. The quality control method for banknote identification includes: obtaining a multispectral signal collected by a contact image sensor (CIS); extracting a first eigenvalue of the multispectral signal; obtaining a corresponding second eigenvalue according to the first eigenvalue and a pre-set correction conversion value; and inputting the second eigenvalue into a banknote classifier to obtain a corresponding banknote classification result.

Abstract: Processing speeds for generating a model can be enhanced. For example, the model can be generated by using regression coefficient values as weights for independent variables in the model. The regression coefficient values can be determined using a coordinate descent method to find a minimum value of a least absolute shrinkage and selection operator cost function. Each iteration of the coordinate descent method can include determining a starting coordinate based on (i) a previous starting coordinate or a previous regression coefficient value from an immediately prior iteration of the coordinate descent method; (ii) a current regression coefficient value associated with a current iteration of the coordinate descent method; and (iii) a refinement factor configured to minimize a result of a univariate algorithm. Each iteration can also include performing a coordinate descent using the starting coordinate to determine a next regression coefficient value for a next iteration of the coordinate descent method.

Abstract: A base station device may include a processor configured to select one or more anchor Narrow Band Internet of Things (NB-IoT) channels in a frequency band based on frequencies consistent with a user equipment (UE) device raster scan and assign a plurality of supplementary NB-IoT channels in the frequency band based on frequencies aligned with Physical Resource Blocks (PRBs) of the frequency band. The base station may further include a transceiver configured to broadcast information identifying the one or more NB-IoT channels and the plurality of supplementary NB-IoT channels in a system information block (SIB).