Patents by Inventor Zhengdong Cheng

Zhengdong Cheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11383234
    Abstract: Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one aspect, the invention relates to systems and methods for making droplets of fluid surrounded by a liquid, using, for example, electric fields, mechanical alterations, the addition of an intervening fluid, etc. In some cases, the droplets may each have a substantially uniform number of entities therein. For example, 95% or more of the droplets may each contain the same number of entities of a particular species. In another aspect, the invention relates to systems and methods for dividing a fluidic droplet into two droplets, for example, through charge and/or dipole interactions with an electric field. The invention also relates to systems and methods for fusing droplets according to another aspect of the invention, for example, through charge and/or dipole interactions. In some cases, the fusion of the droplets may initiate or determine a reaction.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: July 12, 2022
    Assignee: President and Fellows of Harvard College
    Inventors: David A. Weitz, Darren Roy Link, Galder Cristobal-Azkarate, Zhengdong Cheng, Keunho Ahn
  • Publication number: 20220195275
    Abstract: Provided herein are oil herding agents, for example, a biocompatible non-ionic functionalized polysaccharide konjac glucomannan radiation-induced degraded konjac glucomannan. Also provided is a method for containing the spread of an oil spill on a water surface at a low water temperature utilizing the oil herding agent. In addition there is provided a method for preparing an oil herder, a radiation-induced degraded konjac glucomannan prepared by the method and a method for increasing a slick thickness ratio of an oil slick on a water surface utilizing the prepared oil herder.
    Type: Application
    Filed: March 4, 2022
    Publication date: June 23, 2022
    Applicant: Texas A&M University
    Inventors: Zhengdong Cheng, Roshan Sebastian, Lecheng Zhang, Dali Huang, Minxiang Zeng, Abhijeet Shinde, Qingsheng Wang
  • Publication number: 20220097067
    Abstract: This invention generally relates to systems and methods for the formation and/or control of fluidic species, and articles produced by such systems and methods. In some cases, the invention involves unique fluid channels, systems, controls, and/or restrictions, and combinations thereof. In certain embodiments, the invention allows fluidic streams (which can be continuous or discontinuous, i.e., droplets) to be formed and/or combined, at a variety of scales, including microfluidic scales. In one set of embodiments, a fluidic stream may be produced from a channel, where a cross-sectional dimension of the fluidic stream is smaller than that of the channel, for example, through the use of structural elements, other fluids, and/or applied external fields, etc. In some cases, a Taylor cone may be produced.
    Type: Application
    Filed: September 9, 2021
    Publication date: March 31, 2022
    Applicant: President and Fellows of Harvard College
    Inventors: David A. Weitz, Darren Roy Link, Manuel Marquez-Sanchez, Zhengdong Cheng
  • Patent number: 11141731
    Abstract: This invention generally relates to systems and methods for the formation and/or control of fluidic species, and articles produced by such systems and methods. In some cases, the invention involves unique fluid channels, systems, controls, and/or restrictions, and combinations thereof. In certain embodiments, the invention allows fluidic streams (which can be continuous or discontinuous, i.e., droplets) to be formed and/or combined, at a variety of scales, including microfluidic scales. In one set of embodiments, a fluidic stream may be produced from a channel, where a cross-sectional dimension of the fluidic stream is smaller than that of the channel, for example, through the use of structural elements, other fluids, and/or applied external fields, etc. In some cases, a Taylor cone may be produced.
    Type: Grant
    Filed: February 26, 2019
    Date of Patent: October 12, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: David A. Weitz, Darren Roy Link, Manuel Marquez-Sanchez, Zhengdong Cheng
  • Patent number: 10914622
    Abstract: The invention is directed to apparatus for measuring mass flow-rates of the gas, oil and water phases in a wet gas, comprising the following parts: a differential pressure flow meter, having a throat section, and a gamma ray detector, comprising a gamma ray emitter and a gamma ray receiver that are arranged in such a manner that gamma rays emitted from the gamma ray emitter can pass through the throat section in diametrical direction to reach the gamma ray receiver; wherein a radioactive source in the gamma-ray emitter is a multi-energy radioactive source that can naturally emit at least three energy gamma rays, and a thermostatic device is not used in the gamma ray receiver. The invention further relates to a metering method for measuring mass flow-rates of the gas, oil and water phases in a wet gas, in which the above apparatus is used.
    Type: Grant
    Filed: June 12, 2016
    Date of Patent: February 9, 2021
    Assignee: WUXI SEA PIONEERS TECHNOLOGIES CO., LTD.
    Inventors: Jige Chen, Bin Xu, Zhiyong Wu, Zhengdong Cheng, Hongdi Li
  • Publication number: 20200276578
    Abstract: Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one aspect, the invention relates to systems and methods for making droplets of fluid surrounded by a liquid, using, for example, electric fields, mechanical alterations, the addition of an intervening fluid, etc. In some cases, the droplets may each have a substantially uniform number of entities therein. For example, 95% or more of the droplets may each contain the same number of entities of a particular species. In another aspect, the invention relates to systems and methods for dividing a fluidic droplet into two droplets, for example, through charge and/or dipole interactions with an electric field. The invention also relates to systems and methods for fusing droplets according to another aspect of the invention, for example, through charge and/or dipole interactions. In some cases, the fusion of the droplets may initiate or determine a reaction.
    Type: Application
    Filed: March 9, 2020
    Publication date: September 3, 2020
    Applicant: President and Fellows of Harvard College
    Inventors: David A. Weitz, Darren Roy Link, Galder Cristobal-Azkarate, Zhengdong Cheng, Keunho Ahn
  • Patent number: 10625256
    Abstract: Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one aspect, the invention relates to systems and methods for making droplets of fluid surrounded by a liquid, using, for example, electric fields, mechanical alterations, the addition of an intervening fluid, etc. In some cases, the droplets may each have a substantially uniform number of entities therein. For example, 95% or more of the droplets may each contain the same number of entities of a particular species. In another aspect, the invention relates to systems and methods for dividing a fluidic droplet into two droplets, for example, through charge and/or dipole interactions with an electric field. The invention also relates to systems and methods for fusing droplets according to another aspect of the invention, for example, through charge and/or dipole interactions. In some cases, the fusion of the droplets may initiate or determine a reaction.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: April 21, 2020
    Assignee: President and Fellows of Harvard College
    Inventors: David A. Weitz, Darren Roy Link, Galder Cristobal-Azkarate, Zhengdong Cheng, Keunho Ahn
  • Publication number: 20190219432
    Abstract: The invention is directed to apparatus for measuring mass flow-rates of the gas, oil and water phases in a wet gas, comprising the following parts: a differential pressure flow meter, having a throat section, and a gamma ray detector, comprising a gamma ray emitter and a gamma ray receiver that are arranged in such a manner that gamma rays emitted from the gamma ray emitter can pass through the throat section in diametrical direction to reach the gamma ray receiver; wherein a radioactive source in the gamma-ray emitter is a multi-energy radioactive source that can naturally emit at least three energy gamma rays, and a thermostatic device is not used in the gamma ray receiver. The invention further relates to a metering method for measuring mass flow-rates of the gas, oil and water phases in a wet gas, in which the above apparatus is used.
    Type: Application
    Filed: June 12, 2016
    Publication date: July 18, 2019
    Inventors: Jige CHEN, Bin XU, Zhiyong WU, Zhengdong CHENG, Hongdi LI
  • Publication number: 20190184398
    Abstract: This invention generally relates to systems and methods for the formation and/or control of fluidic species, and articles produced by such systems and methods. In some cases, the invention involves unique fluid channels, systems, controls, and/or restrictions, and combinations thereof. In certain embodiments, the invention allows fluidic streams (which can be continuous or discontinuous, i.e., droplets) to be formed and/or combined, at a variety of scales, including microfluidic scales. In one set of embodiments, a fluidic stream may be produced from a channel, where a cross-sectional dimension of the fluidic stream is smaller than that of the channel, for example, through the use of structural elements, other fluids, and/or applied external fields, etc. In some cases, a Taylor cone may be produced.
    Type: Application
    Filed: February 26, 2019
    Publication date: June 20, 2019
    Applicant: President and Fellows of Harvard College
    Inventors: David A. Weitz, Darren Roy Link, Manuel Marquez-Sanchez, Zhengdong Cheng
  • Patent number: 10293341
    Abstract: This invention generally relates to systems and methods for the formation and/or control of fluidic species, and articles produced by such systems and methods. In some cases, the invention involves unique fluid channels, systems, controls, and/or restrictions, and combinations thereof. In certain embodiments, the invention allows fluidic streams (which can be continuous or discontinuous, i.e., droplets) to be formed and/or combined, at a variety of scales, including microfluidic scales. In one set of embodiments, a fluidic stream may be produced from a channel, where a cross-sectional dimension of the fluidic stream is smaller than that of the channel, for example, through the use of structural elements, other fluids, and/or applied external fields, etc. In some cases, a Taylor cone may be produced.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: May 21, 2019
    Assignee: President and Fellows of Harvard College
    Inventors: Darren Roy Link, David A. Weitz, Manuel Marquez-Sanchez, Zhengdong Cheng
  • Patent number: 10258985
    Abstract: This invention generally relates to systems and methods for the formation and/or control of fluidic species, and articles produced by such systems and methods. In some cases, the invention involves unique fluid channels, systems, controls, and/or restrictions, and combinations thereof. In certain embodiments, the invention allows fluidic streams (which can be continuous or discontinuous, i.e., droplets) to be formed and/or combined, at a variety of scales, including microfluidic scales. In one set of embodiments, a fluidic stream may be produced from a channel, where a cross-sectional dimension of the fluidic stream is smaller than that of the channel, for example, through the use of structural elements, other fluids, and/or applied external fields, etc. In some cases, a Taylor cone may be produced.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: April 16, 2019
    Assignee: President and Fellows of Harvard College
    Inventors: Darren Roy Link, David A. Weitz, Manuel Marquez-Sanchez, Zhengdong Cheng
  • Publication number: 20180221829
    Abstract: An interfacial solar membrane includes a substrate with a coating of polypyrrole disposed on a surface of the substrate. The coating of polypyrrole is formed by dipping the substrate in a solution of pyrrole monomer and iron(III) chloride. The interfacial solar membrane can include a coating to improve a hydrophobicity of the interfacial solar membrane, such as a coating of 1H,1H,2H-perfluorooctyltriethoxysilane. A method of using the interfacial solar membrane includes using the interfacial solar membrane to evaporate a fluid and condensing the evaporated fluid to remove an impurity from the fluid.
    Type: Application
    Filed: February 4, 2018
    Publication date: August 9, 2018
    Inventors: Zhengdong Cheng, Yi-Hsien Yu, Xiayun Huang
  • Patent number: 9968898
    Abstract: In some embodiments, the present invention provides amphiphilic nanosheets that comprise lamellar crystals with at least two regions: a first hydrophilic region and a second hydrophobic region. In some embodiments, the amphiphilic nanosheets of the present invention also comprise a plurality of functional groups that are appended to the lamellar crystals. In some embodiments the functional groups are hydrophobic functional groups that are appended to the second region of the lamellar crystals. In some embodiments, the lamellar crystals comprise ?-zirconium phosphates. Additional embodiments of the present invention pertain to methods of making the aforementioned amphiphilic nanosheets. Such methods generally comprise appending one or more functional groups to a stack of lamellar crystals; and exfoliating the stack of lamellar crystals for form the amphiphilic nanosheets.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: May 15, 2018
    Assignee: The Texas A&M University System
    Inventors: Zhengdong Cheng, Andres F. Mejia, Agustin Diaz, Abraham Clearfield, Mahboobul S. Mannan, Ya-Wen Chang
  • Publication number: 20180117585
    Abstract: Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one aspect, the invention relates to systems and methods for making droplets of fluid surrounded by a liquid, using, for example, electric fields, mechanical alterations, the addition of an intervening fluid, etc. In some cases, the droplets may each have a substantially uniform number of entities therein. For example, 95% or more of the droplets may each contain the same number of entities of a particular species. In another aspect, the invention relates to systems and methods for dividing a fluidic droplet into two droplets, for example, through charge and/or dipole interactions with an electric field. The invention also relates to systems and methods for fusing droplets according to another aspect of the invention, for example, through charge and/or dipole interactions. In some cases, the fusion of the droplets may initiate or determine a reaction.
    Type: Application
    Filed: December 1, 2017
    Publication date: May 3, 2018
    Inventors: David A. Weitz, Darren Roy Link, Galder Cristobal-Azkarate, Zhengdong Cheng, Keunho Ahn
  • Patent number: 9878325
    Abstract: Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one aspect, the invention relates to systems and methods for making droplets of fluid surrounded by a liquid, using, for example, electric fields, mechanical alterations, the addition of an intervening fluid, etc. In some cases, the droplets may each have a substantially uniform number of entities therein. For example, 95% or more of the droplets may each contain the same number of entities of a particular species. In another aspect, the invention relates to systems and methods for dividing a fluidic droplet into two droplets, for example, through charge and/or dipole interactions with an electric field. The invention also relates to systems and methods for fusing droplets according to another aspect of the invention, for example, through charge and/or dipole interactions. In some cases, the fusion of the droplets may initiate or determine a reaction.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: January 30, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: David A. Weitz, Darren Roy Link, Galder Cristobal-Azkarate, Zhengdong Cheng, Keunho Ahn
  • Publication number: 20170361318
    Abstract: Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one aspect, the invention relates to systems and methods for making droplets of fluid surrounded by a liquid, using, for example, electric fields, mechanical alterations, the addition of an intervening fluid, etc. In some cases, the droplets may each have a substantially uniform number of entities therein. For example, 95% or more of the droplets may each contain the same number of entities of a particular species. In another aspect, the invention relates to systems and methods for dividing a fluidic droplet into two droplets, for example, through charge and/or dipole interactions with an electric field. The invention also relates to systems and methods for fusing droplets according to another aspect of the invention, for example, through charge and/or dipole interactions. In some cases, the fusion of the droplets may initiate or determine a reaction.
    Type: Application
    Filed: September 5, 2017
    Publication date: December 21, 2017
    Inventors: David A. Weitz, Darren Roy Link, Galder Cristobal-Azkarate, Zhengdong Cheng, Keunho Ahn
  • Patent number: 9789482
    Abstract: Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one aspect, the invention relates to systems and methods for making droplets of fluid surrounded by a liquid, using, for example, electric fields, mechanical alterations, the addition of an intervening fluid, etc. In another aspect, the invention relates to systems and methods for dividing a fluidic droplet into two droplets, for example, through charge and/or dipole interactions with an electric field. The invention also relates to systems and methods for fusing droplets, according to another aspect of the invention, for example, through charge and/or dipole interactions. Another aspect of the invention provides the ability to determine droplets, or a component thereof, for example, using fluorescence and/or other optical techniques (e.g., microscopy), or electric sensing techniques such as dielectric sensing.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: October 17, 2017
    Assignee: President and Fellows of Harvard College
    Inventors: Darren Roy Link, David A. Weitz, Galder Cristobal-Azkarate, Zhengdong Cheng, Keunho Ahn
  • Publication number: 20170173546
    Abstract: In some embodiments, the present invention provides amphiphilic nanosheets that comprise lamellar crystals with at least two regions: a first hydrophilic region and a second hydrophobic region. In some embodiments, the amphiphilic nanosheets of the present invention also comprise a plurality of functional groups that are appended to the lamellar crystals. In some embodiments the functional groups are hydrophobic functional groups that are appended to the second region of the lamellar crystals. In some embodiments, the lamellar crystals comprise ?-zirconium phosphates. Additional embodiments of the present invention pertain to methods of making the aforementioned amphiphilic nanosheets. Such methods generally comprise appending one or more functional groups to a stack of lamellar crystals; and exfoliating the stack of lamellar crystals for form the amphiphilic nanosheets.
    Type: Application
    Filed: March 6, 2017
    Publication date: June 22, 2017
    Inventors: Zhengdong Cheng, Andres F. Mejia, Agustin Diaz, Abraham Clearfield, Mahboobul S. Mannan, Ya-Wen Chang
  • Patent number: 9586983
    Abstract: In some embodiments, the present invention provides amphiphilic nanosheets that comprise lamellar crystals with at least two regions: a first hydrophilic region, and a second hydrophobic region. In some embodiments, the amphiphilic nanosheets of the present invention also comprise a plurality of functional groups that are appended to the lamellar crystals. In some embodiments, the functional groups are hydrophobic functional groups that are appended to the second region of the lamellar crystals. In some embodiments, the lamellar crystals comprise ?-zirconium phosphates. Additional embodiments of the present invention pertain to methods of making the aforementioned amphiphilic nanosheets. Such methods generally comprise appending one or more functional groups to a stack of lamellar crystals; and exfoliating the stack of lamellar crystals for form the amphiphilic nanosheets.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: March 7, 2017
    Assignee: The Texas A&M University System
    Inventors: Zhengdong Cheng, Andres F. Mejia, Agustin Diaz, Abraham Clearfield, Mahboobul S Mannan, Ya-Wen Chang
  • Publication number: 20150299240
    Abstract: In some embodiments, the present invention provides amphiphilic nanosheets that comprise lamellar crystals with at least two regions: a first hydrophilic region, and a second hydrophobic region. In some embodiments, the amphiphilic nanosheets of the present invention also comprise a plurality of functional groups that are appended to the lamellar crystals. In some embodiments, the functional groups are hydrophobic functional groups that are appended to the second region of the lamellar crystals. In some embodiments, the lamellar crystals comprise ?-zirconium phosphates. Additional embodiments of the present invention pertain to methods of making the aforementioned amphiphilic nanosheets. Such methods generally comprise appending one or more functional groups to a stack of lamellar crystals; and exfoliating the stack of lamellar crystals for form the amphiphilic nanosheets.
    Type: Application
    Filed: February 18, 2015
    Publication date: October 22, 2015
    Applicant: The Texas A&M University System
    Inventors: Zhengdong Cheng, Andres F. MEJIA, Agustin DIAZ, Abraham CLEARFIELD, Mahboobul S. MANNAN, Ya-Wen CHANG