Patents by Inventor Zhengjian Zhang

Zhengjian Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200048324
    Abstract: The present disclosure provides tissue-specific Wnt signal enhancing molecules, and related methods of using these molecules to increase Wnt signaling in targeted tissues.
    Type: Application
    Filed: January 26, 2018
    Publication date: February 13, 2020
    Inventors: Zhengjian ZHANG, Jennifer Jean BRADY, Aaron Ken SATO, Wen-Chen YEH, Yang LI, Teppei YAMAGUCHI
  • Patent number: 10495632
    Abstract: The presently-disclosed subject matter includes azetidine-substituted fluorescent compounds, where the compounds may be used as probes, dyes, tags, and the like. The presently-disclosed subject matter also includes kits comprising the same as well as methods for using the same to detect a target substance.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: December 3, 2019
    Assignee: HOWARD HUGHES MEDICAL INSTITUTE
    Inventors: Luke D. Lavis, Jonathan B. Grimm, Jiji Chen, Timothee Lionnet, Zhengjian Zhang, Andrey Revyakin, Joel Slaughter
  • Patent number: 10316662
    Abstract: A construction layout for underground caverns in a nuclear island powerhouse of an underground nuclear power plant, including: two primary caverns accomodating nuclear reactor powerhouses, combined caverns, electric powerhouse caverns, pressure relief caverns, a first primary traffic tunnel, a second primary traffic tunnel, a third primary traffic tunnel, a top adit system, a ground adit system, secondary traffic tunnels, and a side traffic tunnel. Each combined cavern and each electric powerhouse cavern are disposed at two sides of each primary cavern, respectively. Two combined caverns are in end-to-end connection and the arrangement direction of the two combined caverns are in parallel to the connecting line of the medial axes of the two primary caverns. Each pressure relief cavern is disposed between each combined cavern and a corresponding electric powerhouse cavern.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: June 11, 2019
    Assignee: CHANGJIANG SURVEY PLANNING DESIGN AND RESEARCH CO., LTD.
    Inventors: Qigui Yang, Xinqiang Niu, Lixin Liu, Baixing Liu, Xin Zhao, Lijun Su, Feng Li, Xuehong Yang, Zhijun Zhang, Zhengjian Miu, Zhiguo Zhang, Haibo Liu, Tieling Tao, Yanlei Wan
  • Publication number: 20190107534
    Abstract: The presently-disclosed subject matter includes azetidine-substituted fluorescent compounds, where the compounds may be used as probes, dyes, tags, and the like. The presently-disclosed subject matter also includes kits comprising the same as well as methods for using the same to detect a target substance.
    Type: Application
    Filed: December 6, 2018
    Publication date: April 11, 2019
    Inventors: Luke D. LAVIS, Jonathan B. GRIMM, Jiji CHEN, Timothee LIONNET, Zhengjian ZHANG, Andrey REVYAKIN, Joel SLAUGHTER
  • Patent number: 10161932
    Abstract: The presently-disclosed subject matter includes azetidine-substituted fluorescent compounds, where the compounds may be used as probes, dyes, tags, and the like. The presently-disclosed subject matter also includes kits comprising the same as well as methods for using the same to detect a target substance.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: December 25, 2018
    Assignee: HOWARD HUGHES MEDICAL INSTITUTE
    Inventors: Luke D. Lavis, Jonathan B. Grimm, Jiji Chen, Timothee Lionnet, Zhengjian Zhang, Andrey Revyakin, Joel Slaughter
  • Publication number: 20180284105
    Abstract: The presently-disclosed subject matter includes azetidine-substituted fluorescent compounds, where the compounds may be used as probes, dyes, tags, and the like. The presently-disclosed subject matter also includes kits comprising the same as well as methods for using the same to detect a target substance.
    Type: Application
    Filed: June 5, 2018
    Publication date: October 4, 2018
    Inventors: Luke D. LAVIS, Jonathan B. GRIMM, Jiji CHEN, Timothee LIONNET, Zhengjian ZHANG, Andrey REVYAKIN, Joel SLAUGHTER
  • Patent number: 10018624
    Abstract: The presently-disclosed subject matter includes azetidine-substituted fluorescent compounds, where the compounds may be used as probes, dyes, tags, and the like. The presently-disclosed subject matter also includes kits comprising the same as well as methods for using the same to detect a target substance.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: July 10, 2018
    Assignee: HOWARD HUGHES MEDICAL INSTITUTE
    Inventors: Luke D. Lavis, Jonathan B. Grimm, Jiji Chen, Timothee Lionnet, Zhengjian Zhang, Andrey Revyakin, Joel Slaughter
  • Publication number: 20180172677
    Abstract: The presently-disclosed subject matter includes azetidine-substituted fluorescent compounds, where the compounds may be used as probes, dyes, tags, and the like. The presently-disclosed subject matter also includes kits comprising the same as well as methods for using the same to detect a target substance.
    Type: Application
    Filed: February 15, 2018
    Publication date: June 21, 2018
    Inventors: Luke D. LAVIS, Jonathan B. GRIMM, Jiji CHEN, Timothee LIONNET, Zhengjian ZHANG, Andrey REVYAKIN, Joel SLAUGHTER
  • Patent number: 9933417
    Abstract: The presently-disclosed subject matter includes azetidine-substituted fluorescent compounds, where the compounds may be used as probes, dyes, tags, and the like. The presently-disclosed subject matter also includes kits comprising the same as well as methods for using the same to detect a target substance.
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: April 3, 2018
    Assignee: HOWARD HUGHES MEDICAL INSTITUTE
    Inventors: Luke D. Lavis, Jonathan B. Grimm, Jiji Chen, Timothee Lionnet, Zhengjian Zhang, Andrey Revyakin, Joel Slaughter
  • Publication number: 20120231447
    Abstract: The present disclosure provides methods for treating a surface for single-molecule imaging.
    Type: Application
    Filed: February 15, 2012
    Publication date: September 13, 2012
    Applicant: HOWARD HUGHES MEDICAL INSTITUTE
    Inventors: Zhengjian Zhang, Andrey Revyakin, Steve Chu, Robert Tijan