Patents by Inventor Zhengliang Ye

Zhengliang Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11013694
    Abstract: The present invention relates to a preparation method for a traditional Chinese medicine drop pill and a traditional Chinese medicine micro drop pill prepared by using the method, and in particular, the present invention relates to a micro drop pill preparation method with high drug-loading capacity, simple preparation process and high production rate and a micro drop pill prepared by using the method. Specially, The drop pill preparation method used comprises the following steps: (1) material melting step: heat melting a medicine and a drop pill matrix to obtain a molten medicine liquid; (2) dropping step: delivering the molten medicine liquid to a dripper, and acquiring medicine drops of the molten medicine liquid by means of vibration dropping; and, (3) condensation step: cooling the medicine drops with a cooling gas to obtain micro drop pills.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: May 25, 2021
    Assignee: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Xiaobing Sun, Shunnan Zhang, Zhengliang Ye, Hai'ou Dong, Hongbo Zhang, Wensheng Zhang, Lihong Zhou, Chenming Li, Cong Chen, Xiaofeng Liu, Shiqing Wang, Changsheng Rong, Yongfeng Zheng, Lijun Fan
  • Publication number: 20190274962
    Abstract: The present invention relates to a preparation method for a traditional Chinese medicine drop pill and a traditional Chinese medicine micro drop pill prepared by using the method, and in particular, the present invention relates to a micro drop pill preparation method with high drug-loading capacity, simple preparation process and high production rate and a micro drop pill prepared by using the method. Specially, The drop pill preparation method used comprises the following steps: (1) material melting step: heat melting a medicine and a drop pill matrix to obtain a molten medicine liquid; (2) dropping step: delivering the molten medicine liquid to a dripper, and acquiring medicine drops of the molten medicine liquid by means of vibration dropping; and, (3) condensation step: cooling the medicine drops with a cooling gas to obtain micro drop pills.
    Type: Application
    Filed: May 24, 2019
    Publication date: September 12, 2019
    Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Xiaobing Sun, Shunnan Zhang, Zhengliang Ye, Hai'ou Dong, Hongbo Zhang, Wensheng Zhang, Lihong Zhou, Chenming Li, Cong Chen, Xiaofeng Liu, Shiqing Wang, Changsheng Rong, Yongfeng Zheng, Lijun Fan
  • Patent number: 10300030
    Abstract: A traditional Chinese medicine composition and preparation thereof for treating cardiovascular diseases is provided. The traditional Chinese medicine composition consists of: by weight percentage, phenolic acid derivatives 30%˜80%, tanshinones 2%˜10% and saponins 15%˜60%.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: May 28, 2019
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Shunnan Zhang, Ping Li, Zhengliang Ye, Lihong Zhou, Lianwen Qi, Fenglian Zhang, Minchao Qi, Zhexuan Yang, Wei Sun, Jing Yu, Hua Yang, Peng Liu, Xiaohui Ma, Hai'ou Dong, Wensheng Zhang, Lanlan Zhang, Chenming Li
  • Patent number: 9999630
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: June 19, 2018
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong
  • Patent number: 9987320
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: June 5, 2018
    Assignee: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong, Yongfeng Zheng, Lijun Fan
  • Publication number: 20170157156
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Application
    Filed: July 11, 2014
    Publication date: June 8, 2017
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong
  • Publication number: 20160184249
    Abstract: A traditional Chinese medicine composition and preparation thereof for treating cardiovascular diseases is provided. The traditional Chinese medicine composition consists of: by weight percentage, phenolic acid derivatives 30%˜80%, tanshinones 2%˜10% and saponins 15%˜60%.
    Type: Application
    Filed: August 28, 2014
    Publication date: June 30, 2016
    Applicant: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Shunnan Zhang, Ping Li, Zhengliang Ye, Lihong Zhou, Lianwen Qi, Fenglian Zhang, Minchao Qi, Zhexuan Yang, Wei Sun, Jing Yu, Hua Yang, Peng Liu, Xiaohui Ma, Hai'ou Dong, Wensheng Zhang, Lanlan Zhang, Chenming Li
  • Publication number: 20160175336
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Application
    Filed: July 11, 2014
    Publication date: June 23, 2016
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong
  • Publication number: 20160151293
    Abstract: The present invention relates to a preparation method for a traditional Chinese medicine drop pill and a traditional Chinese medicine micro drop pill prepared by using the method, and in particular, the present invention relates to a micro drop pill preparation method with high drug-loading capacity, simple preparation process and high production rate and a micro drop pill prepared by using the method. Specially, The drop pill preparation method used comprises the following steps: (1) material melting step: heat melting a medicine and a drop pill matrix to obtain a molten medicine liquid; (2) dropping step: delivering the molten medicine liquid to a dripper, and acquiring medicine drops of the molten medicine liquid by means of vibration dropping; and, (3) condensation step: cooling the medicine drops with a cooling gas to obtain micro drop pills.
    Type: Application
    Filed: July 11, 2014
    Publication date: June 2, 2016
    Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Xiaobing Sun, Shunnan Zhang, Zhengliang Ye, Hai'ou Dong, Hongbo Zhang, Wensheng Zhang, Lihong Zhou, Chenming Li, Cong Chen, Xiaofeng Liu, Shiqing Wang, Changsheng Rong, Yongfeng Zheng, Lijun Fan
  • Publication number: 20160143976
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Application
    Filed: July 11, 2014
    Publication date: May 26, 2016
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong, Yongfeng Zheng, Lijun Fan
  • Patent number: 8883228
    Abstract: This invention provides a composition for heart disease comprising extracts from raw herbs of 80.0-97.0% Radix Salviae Miltorrhizae, 1.0-19.0% Panax Notoginseng and 0.1-1.0% Borneol and its active ingredients. This invention also provides a method for preparing said composition and the active ingredients of the composition. Finally, this invention provides various uses of said compositions and the active ingredients.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: November 11, 2014
    Assignee: Tasly Pharmaceutical Group Co. Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Zhixin Guo, Zhengliang Ye, Yan Liu
  • Patent number: 8747913
    Abstract: A pharmaceutical composition consisting of Radix Polygoni Multiflori extract, Salviae Miltiorrhizae extract, Fructus Crataegi extract and Radix Notoginseng extract is described, wherein the composition optionally contains a pharmaceutical carrier. Processes for producing the composition and methods for treating and/or preventing hyperlipidemia, treating and/or preventing fatty liver and lowering blood lipid level by administration of the pharmaceutical composition are also disclosed.
    Type: Grant
    Filed: December 5, 2005
    Date of Patent: June 10, 2014
    Assignee: Tasly Pharmaceutical Group Co., Ltd
    Inventors: Xijun Yan, Boli Zhang, Zhixin Guo, Guoguang Zhu, Zhengliang Ye, Feng Wei, Ruizhi Luo
  • Patent number: 8586108
    Abstract: The present invention relates to plant extracts, specifically, the extracts of Chinese medicine Chenopodium ambrosioides L. and the composition comprising thereof. The extracts of Chinese medicine Chenopodium ambrosioides L. are prepared by conventional methods for the extraction of volatile oil, and can be used to treat Helicobacter Pylori-induced diseases of digestive system, such as gastritis, gastric ulcer, etc., with easy availability of raw materials, simple preparations, prominent effects, and less side-effect.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: November 19, 2013
    Assignee: Tasly Pharmaceutical Group Co., Ltd
    Inventors: Zhengliang Ye, Yonghong Zhu, Ying Zhao, Dekun Li, XiaoLi Zheng, Chongnian Luo, Feng Wei, GuangMing Zhang, JianMing Chen, Jun Gao, JunFeng Xiong
  • Patent number: 8486464
    Abstract: This invention provides compositions comprising extracts of Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneol. Said compositions comprise notoginsenoside R1 and ginsenoside Rg1 which are active components for therapeutic applications. This invention also provides a method of preparation of the said compositions and a method of identification and determination of the amount of individual effective components of said compositions. Finally, this invention provides various uses of the compositions.
    Type: Grant
    Filed: July 31, 2002
    Date of Patent: July 16, 2013
    Assignee: Tasly Pharmaceutical Group Co. Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Zhixin Guo, Zhengliang Ye, Yan Liu
  • Publication number: 20130178516
    Abstract: The present invention relates to plant extracts, specifically, the extracts of Chinese medicine Chenopodium ambrosioides L. and the composition comprising thereof. The extracts of Chinese medicine Chenopodium ambrosioides L. are prepared by conventional methods for the extraction of volatile oil, and can be used to treat Helicobacter Pylori -induced diseases of digestive system, such as gastritis, gastric ulcer, etc., with easy availability of raw materials, simple preparations, prominent effects, and less side-effect.
    Type: Application
    Filed: December 21, 2012
    Publication date: July 11, 2013
    Applicant: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Feng Wei, Zhengliang Ye, Jun Gao, Chongnian Luo, Dekun Li, Jianming Chen, Yonghong Zhu, Junfeng Xiong, Xiaoli Zheng, Guangming Zhang, Ying Zhao
  • Patent number: 8361515
    Abstract: The present invention relates to plant extracts, specifically, the extracts of Chinese medicine Chenopodium ambrosioides L. and the composition comprising thereof. The extracts of Chinese medicine Chenopodium ambrosioides L. are prepared by conventional methods for the extraction of volatile oil, and can be used to treat Helicobacter Pylori-induced diseases of digestive system, such as gastritis, gastric ulcer, etc., with easy availability of raw materials, simple preparations, prominent effects, and less side-effect.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: January 29, 2013
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Feng Wei, Zhengliang Ye, Jun Gao, Chongnian Luo, Dekun Li, Jianming Chen, Yonghong Zhu, Junfeng Xiong, Xiaoli Zheng, Guangming Zhang, Ying Zhao
  • Publication number: 20100136146
    Abstract: This invention provides a composition for heart disease comprising extracts from raw herbs of 80.0-97.0% Radix Salviae Miltorrhizae, 1.0-19.0% Panax Notoginseng and 0.1-1.0% Borneol and its active ingredients. This invention also provides a method for preparing said composition and the active ingredients of the composition. Finally, this invention provides various uses of said compositions and the active ingredients.
    Type: Application
    Filed: February 16, 2010
    Publication date: June 3, 2010
    Inventors: Xijun YAN, Naifeng WU, Zhixin GUO, Zhengliang YE, Yan LIU
  • Patent number: 7641922
    Abstract: A process for preparing tanshintotalphenolic acid and the use of the product are disclosed. The process comprises: tanshin is hot-extracted with water, the extract is separated and refined by polyamide column and macroporous adsorption resin column, and lyophilized to obtain tanshintotalphenolic acid. The yield of the final end product is more than 4 percent based on the amount of crude drug and the content of totalphenolic acid is more than 80 percent. The tanshintotalphenolic acid obtained can be used as the medicine for preventing and treating cerebrovascular and cardiovascular diseases and so on.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: January 5, 2010
    Assignee: Tianjin Tasly Pharmaceutical Co., Ltd.
    Inventors: Feng Wei, Hongshui Yue, Dekun Li, Jiangxiao Sun, Zhengliang Ye, Xu Li
  • Patent number: RE49035
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Grant
    Filed: December 16, 2019
    Date of Patent: April 19, 2022
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong
  • Patent number: RE49050
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: April 26, 2022
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong, Yongfeng Zheng, Lijun Fan