Patents by Inventor Zhenglun Zhu

Zhenglun Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of immune disorders with Hom-1 inhibitors
    Patent number: 8741865
    Abstract: Disclosed are methods for treating immune disorders using inhibitors of Hom-1. The inhibitors include an RNAi agent containing the sequence of SEQ ID NO: 6.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: June 3, 2014
    Inventors: Zhenglun Zhu, Hong Gao
  • Expanding hematopoietic stem cells
    Patent number: 8741640
    Abstract: A method of expanding hematopoietic stem cells. Also disclosed is a method of diagnosing primary or secondary bone marrow failure syndrome. The invention further includes a method of treating primary or secondary bone marrow failure syndrome.
    Type: Grant
    Filed: November 23, 2011
    Date of Patent: June 3, 2014
    Inventors: Hong Gao, Zhenglun Zhu
  • TREATMENT OF DEVELOPMENT-RELATED DISORDERS
    Publication number: 20130280261
    Abstract: Disclosed are composition and methods for treating development-related disorders. Also disclosed are diagnosis methods, prognosis methods, and drug screening methods.
    Type: Application
    Filed: April 9, 2013
    Publication date: October 24, 2013
    Inventors: Zhenglun Zhu, Hong Gao
  • TREATMENT AND DIAGNOSIS OF IMMUNE DISORDERS
    Publication number: 20120183553
    Abstract: Disclosed are composition and methods for treating immune disorders. Also disclosed are diagnosis methods and prognosis methods.
    Type: Application
    Filed: July 15, 2010
    Publication date: July 19, 2012
    Inventors: Zhenglun Zhu, Hong Gao
  • EXPANDING HEMATOPOIETIC STEM CELLS
    Publication number: 20120164112
    Abstract: A method of expanding hematopoietic stem cells. Also disclosed is a method of diagnosing primary or secondary bone marrow failure syndrome. The invention further includes a method of treating primary or secondary bone marrow failure syndrome.
    Type: Application
    Filed: November 23, 2011
    Publication date: June 28, 2012
    Inventors: Hong Gao, Zhenglun Zhu
  • Treatment of Development-Related Disorders
    Publication number: 20110300549
    Abstract: Disclosed are composition and methods for treating development-related disorders. Also disclosed are diagnosis methods, prognosis methods, and drug screening methods.
    Type: Application
    Filed: August 9, 2011
    Publication date: December 8, 2011
    Inventors: Zhenglun Zhu, Hong Gao
  • Treatment of cellular proliferative disorders with compositions comprising Hom polypeptide (also known as Xom, VENTX2)
    Patent number: 7994126
    Abstract: Disclosed are compositions comprising Hom polypeptide (also known as Xom, Ventx2) and methods for treating cellular proliferative disorders comprising. Also disclosed are diagnosis methods, prognosis methods, and drug screening methods.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: August 9, 2011
    Inventors: Zhenglun Zhu, Hong Gao
  • Genetically engineered cell lines and systems for propagating varicella zoster virus and methods of use thereof
    Publication number: 20080279888
    Abstract: The present invention provides genetically engineered cell lines, recombinant vectors, and vaccines. The present invention also provides methods for generating an in vitro system for Varicella zoster virus (VZV), and the in vitro systems generated by these methods. The present invention further provides methods for reactivating VZV, and VZV reactivated by these methods. Finally, the present invention provides a method of screening for an agent for treating VZV infection.
    Type: Application
    Filed: September 24, 2007
    Publication date: November 13, 2008
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Michael D. Gershon, Zhenglun Zhu, Saul Silverstein, Anne A. Gershon
  • TREATMENT OF DEVELOPMENT-RELATED DISORDERS
    Publication number: 20080032927
    Abstract: Disclosed are composition and methods for treating development-related disorders. Also disclosed are diagnosis methods, prognosis methods, and drug screening methods.
    Type: Application
    Filed: February 22, 2007
    Publication date: February 7, 2008
    Inventors: Zhenglun Zhu, Hong Gao
  • Genetically engineered cell lines and systems for propagating virus and methods of use thereof
    Patent number: 7273616
    Abstract: The present invention provides genetically engineered cell lines, recombinant vectors, and vaccines. The present invention also provides methods for generating an in vitro system for Varicella zoster virus (VZV), and the in vitro systems generated by these methods. The present invention further provides methods for reactivating VZV, and VZV reactivated by these methods. Finally, the present invention provides a method of screening for an agent for treating VZV infection.
    Type: Grant
    Filed: May 12, 2003
    Date of Patent: September 25, 2007
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Jason J. Chen, Anne A. Gershon, Zhenglun Zhu, Saul Silverstein, Michael D. Gershon
  • Genetically engineered cell lines and systems for propagating Varicella zoster virus and methods of use thereof
    Publication number: 20060121048
    Abstract: The present invention provides genetically engineered cell lines, recombinant vectors, and vaccines. The present invention also provides methods for generating an in vitro system for Varicella zoster virus (VZV), and the in vitro systems generated by these methods. The present invention further provides methods for reactivating VZV, and VZV reactivated by these methods. Finally, the present invention provides a method of screening for an agent for treating VZV infection.
    Type: Application
    Filed: May 12, 2003
    Publication date: June 8, 2006
    Inventors: Jason Chen, Anne Gershon, Zhenglun Zhu, Saul Silverstein, Michael Gershon