Abstract: Provided herein are methods of administering gapmer oligomeric compounds with GalNAc conjugate groups to a human.

Abstract: A method and system for collaborative order are provided. The method may include receiving a collaborative order request, containing commodity information, sent by a subscriber. A related user of the subscriber may be identified from a set of users related to the subscriber. A collaborative order invitation for the commodity may be sent to the related user to invite the related user to send sub-order information for the commodity. Order information for the commodity sent by the subscriber and sub-order information for the commodity sent by the related user may be received and combined, to obtain combined order information. The combined order information may be sent to a trading platform for processing trade of the commodity by processing the combined order information.

Abstract: This invention relates to a laborsaving lighter, and more particularly relates to a laborsaving and safe lighter, which includes a casing (101), and a piezoelectric assembly and a gas emitting assembly disposed in the casing. The piezoelectric assembly includes a piezoelectric push rod (104) and a button (105). A vertical slot opening (106) is formed in the end face of the button (105), and a safety piece (107) is disposed in the slot opening (106). There is a rock arm (109) between the gas emitting assembly and the safety piece (107). In the lighter's non-operative state, the upper end of the rock arm (109) rests against the lower part (107a) of the safety piece (107). The middle part of the rock arm is contacted with the piezoelectric push rod (104), and the lower end of the rock arm is connected pivotally to the inner surface of the casing (101). According to the principle of lever, the present invention is laborsaving as well as safety.

Abstract: This invention relates to a laborsaving cigarette lighter and more particularly relates to a laborsaving and safety cigarette lighter, which includes a casing (101), a piezoelectric assembly and a gas releasing assembly disposed in the casing. The piezoelectric assembly includes a piezoelectric push rod (104) and a button (105). There is a slot (106) on the button (105), and safety piece (107) is disposed in the slot (106). There is a rocker arm (109) between the gas releasing assembly and the safety piece (107), and in the non-operative state, the upper end of the rocker arm (109) is opposite to the lower part (107a) of the safety piece (107). The middle part of the rocker arm is contacted with the push rod (104), and the lower end of the rocker arm is connected pivotally to the inner surface of the casing (101). According to the principle of lever, present invention is laborsaving as well as safety.

Abstract: A method and apparatus for adaptive bit allocation and hybrid lossless entropy encoding in a lossy compression system. The invention includes three components: (1) a transform stage to decorrelate image data into a baseband and multiple subbands, (2) a quantization stage to quantize the resulting transform coefficients, and (3) a lossless entropy coder stage to encode the quantized indexes. In the preferred embodiment, the transform stage uses a wavelet transform algorithm. The quantization stage adaptively estimates values for parameters defining an approximation between quantization size and the logarithm of quantization error, and recursively calculates the optimal quantization size for each band to achieve a desired bit rate. The baseband and subbands are transformed into quantization matrices using the corresponding quantization sizes.

Abstract: A method and apparatus for adaptive bit allocation and hybrid lossless entropy encoding in a lossy compression system. The invention includes three components: (1) a transform stage to decorrelate image data into a baseband and multiple subbands, (2) a quantization stage to quantize the resulting transform coefficients, and (3) a lossless entropy coder stage to encode the quantized indexes. In the preferred embodiment, the transform stage uses a wavelet transform algorithm. The quantization stage adaptively estimates values for parameters defining an approximation between quantization size and the logarithm of quantization error, and recursively calculates the optimal quantization size for each band to achieve a desired bit rate. The baseband and subbands are transformed into quantization matrices using the corresponding quantization sizes.