Patents by Inventor Zhengxin Cai

Zhengxin Cai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radiolabeled pharmaceuticals and methods of making and using same
    Patent number: 11518754
    Abstract: In one aspect, the invention comprises compounds that bind to the synaptic vesicle protein SV2A and that can be useful as radiotracers for positron emission tomography. In another aspect, the invention comprises methods of imaging the brain, measuring synaptic density or diagnosing neurological diseases such as Alzheimer's disease, psychiatric disorders such as depression, and metabolic disorders such as diabetes comprising detecting the compounds of the invention by positron emission tomography (PET).
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: December 6, 2022
    Assignee: YALE UNIVERSITY
    Inventors: Yiyun Huang, Zhengxin Cai, Songye Li, Nabeel Nabulsi, Richard Carson
  • Radiolabeled Pharmaceuticals and Methods of Making and Using Same
    Publication number: 20200010447
    Abstract: In one aspect, the invention comprises compounds that bind to the synaptic vesicle protein SV2A and that can be useful as radiotracers for positron emission tomography. In another aspect, the invention comprises methods of imaging the brain, measuring synaptic density or diagnosing neurological diseases such as Alzheimer's disease, psychiatric disorders such as depression, and metabolic disorders such as diabetes comprising detecting the compounds of the invention by positron emission tomography (PET).
    Type: Application
    Filed: February 15, 2018
    Publication date: January 9, 2020
    Inventors: Yiyun Huang, Zhengxin Cai, Songye Li, Nabeel Nabulsi, Richard Carson
  • FATTY ACID ANALOGS AND THEIR USE
    Publication number: 20160185735
    Abstract: Embodiments of novel fatty acid analogs, precursors of such analogs, pharmaceutical compositions including same, and methods of their use are disclosed. In several embodiments, the disclosed fatty acid analogs can be used to detect and monitor ?-oxidation in cells and tissue, for example, in methods of detecting a tumor, such as a prostate tumor.
    Type: Application
    Filed: August 12, 2014
    Publication date: June 30, 2016
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Carolyn Anderson, Zhengxin Cai, Bennett Van Houten, Wilson B Edwards