Patents by Inventor Zhenhai Gao

Zhenhai Gao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200385005
    Abstract: The present invention discloses a bend control optimization method and system. The bend control optimization method includes: acquiring lateral motion data of a vehicle, where the lateral motion data includes a steering angle; determining a lateral acceleration according to the lateral motion data; determining a longitudinal acceleration pre-correction amount of the vehicle according to the lateral motion data and the lateral acceleration; determining a longitudinal acceleration correction amount according to the longitudinal acceleration pre-correction amount; and adjusting longitudinal acceleration of the vehicle according to the longitudinal acceleration correction amount to assist the vehicle to conduct bend driving.
    Type: Application
    Filed: February 27, 2020
    Publication date: December 10, 2020
    Inventors: Zhenhai GAO, Yiteng SUN, Hongyu HU, Fei GAO, Yichi ZHANG, Naixuan ZHU, Yuhuan SHENG
  • Patent number: 10576859
    Abstract: The present invention provides an array type automobile seat profile adaptive-adjusting apparatus, comprising a seat back plate, a seat bottom plate, a seat profile layer covered thereon and a plurality of shape memory material actuators which are arranged in a rectangular array and are disposed between the seat profile layer and the seat back plate and between the seat profile layer and the seat bottom plate, wherein each of the shape memory material actuators comprises a plurality of sequentially nested sleeves, a return spring through which an outwardly extending elastic force is applied to the sleeves, a pulley block fixedly arranged in the sleeve located at a tail end, and a memory alloy wire which is in a shape of filament and is wound on the pulley block.
    Type: Grant
    Filed: December 17, 2017
    Date of Patent: March 3, 2020
    Inventors: Zhenhai Gao, Chuanliang Shen, Binyu Zhou, Tairong Sun, Fei Gao
  • Publication number: 20190135150
    Abstract: The present invention provides an array type automobile seat profile adaptive-adjusting apparatus, comprising a seat back plate, a seat bottom plate, a seat profile layer covered thereon and a plurality of shape memory material actuators which are arranged in a rectangular array and are disposed between the seat profile layer and the seat back plate and between the seat profile layer and the seat bottom plate, wherein each of the shape memory material actuators comprises a plurality of sequentially nested sleeves, a return spring through which an outwardly extending elastic force is applied to the sleeves, a pulley block fixedly arranged in the sleeve located at a tail end, and a memory alloy wire which is in a shape of filament and is wound on the pulley block.
    Type: Application
    Filed: December 17, 2017
    Publication date: May 9, 2019
    Inventors: ZHENHAI GAO, CHUANLIANG SHEN, BINYU ZHOU, TAIRONG SUN, FEI GAO
  • Patent number: 9163057
    Abstract: The present invention provides a method of myocardial perfusion imaging using reduced doses of (1-{9-[(4S,2R,3R,5R)3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-N-methylcarboxamide.
    Type: Grant
    Filed: August 29, 2013
    Date of Patent: October 20, 2015
    Assignee: Gilead Sciences, Inc.
    Inventors: Luiz Belardinelli, Brent K. Blackburn, Zhenhai Gao
  • Publication number: 20150023867
    Abstract: The present invention provides a method of myocardial perfusion imaging using reduced doses of (1-{9-[(4S,2R,3R,5R)3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-N-methylcarboxamide.
    Type: Application
    Filed: August 29, 2013
    Publication date: January 22, 2015
    Applicant: Gilead Sciences, Inc.
    Inventors: Luiz Belardinelli, Brent K. Blackburn, Zhenhai Gao
  • Publication number: 20140005070
    Abstract: The invention provides methods of monitoring differential gene expression of pharmacodynamic (PD) markers in a patient treated with a Cyclin Dependent Kinase Inhibitor (CDKI), methods of determining the sensitivity of a cell to a CDKI by measuring PD markers and methods of screening for candidate CKDI.
    Type: Application
    Filed: March 28, 2012
    Publication date: January 2, 2014
    Applicant: Novartis AG
    Inventors: Michel Faure, Zhenhai Gao, James Sutton, Guoying Karen Yu
  • Patent number: 8536150
    Abstract: The present invention provides a method of myocardial perfusion imaging using reduced doses of (1-{9-[(4S,2R,3R,5R)3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-N-methylcarboxamide.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: September 17, 2013
    Assignee: Gilead Sciences, Inc.
    Inventors: Luiz Belardinelli, Brent K. Blackburn, Zhenhai Gao
  • Publication number: 20120251440
    Abstract: The present invention provides a method for identifying and using partial adenosine A2A receptor agonists that are useful as adjuncts in myocardiological perfusion imaging.
    Type: Application
    Filed: June 15, 2012
    Publication date: October 4, 2012
    Applicant: Gilead Sciences, Inc.
    Inventors: Luiz Belardinelli, Brent K. Blackburn, Zhenhai Gao
  • Patent number: 8071566
    Abstract: The present invention provides methods of myocardial perfusion imaging and increasing coronary blood flow of a mammal that are accomplished by administering doses of a compound that is a selective partial A2A receptor agonist with a short duration of action, in particular regadenoson, useful for, among other indications, myocardial imaging and coronary vasodilation, and determining areas of insufficient blood flow.
    Type: Grant
    Filed: May 4, 2009
    Date of Patent: December 6, 2011
    Assignee: Gilead Sciences, Inc.
    Inventors: Luiz Belardinelli, Brent K. Blackburn, Zhenhai Gao
  • Patent number: 7671059
    Abstract: Disclosed are 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Disclosed also are methods of using the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative, viral, autoimmune, cardiovascular, and central nervous system diseases.
    Type: Grant
    Filed: September 28, 2006
    Date of Patent: March 2, 2010
    Assignee: Novartis AG
    Inventors: Timothy D. Machajewski, Cynthia M. Shafer, Christopher McBride, William Antonios-McCrea, Brandon M. Doughan, Barry H. Levine, Yi Xia, Maureen McKenna, X. Michael Wang, Kris Mendenhall, Yasheen Zhou, Kristin Brinner, Zhenhai Gao, Daniel Poon, Paul Barsanti, Xiaodong Lin, Abran Costales, Alice Rico, Nathan Brammeier, Teresa Pick, Paul A. Renhowe
  • Publication number: 20100004237
    Abstract: Disclosed are 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Disclosed also are methods of using the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative, viral, autoimmune, cardiovascular, and central nervous system diseases.
    Type: Application
    Filed: July 31, 2009
    Publication date: January 7, 2010
    Inventors: Timothy D. Machakewski, Cynthia M. Shafer, Christopher McBride, William Antonios-McCrea, Brandon M. Doughan, Barry H. Levine, Yi Xia, Maureen McKenna, X. Michael Wang, Kris Mendenhall, Yasheen Zhou, Baoqing Gong, Dan Gu, John Dolan, John Tulinsky, Kristin Brinner, Zhenhai Gao, Daniel Poon, Paul Barsanti, Xiaodong Lin, Abran Costales, Alice Rico, Nathan Brammeier, Teresa Pick, Paul A. Renhowe
  • Publication number: 20090317331
    Abstract: The present invention provides a method for identifying and using partial adenosine A2A receptor agonists that are useful as adjuncts in myocardiological perfusion imaging.
    Type: Application
    Filed: May 4, 2009
    Publication date: December 24, 2009
    Inventors: Luiz Belardinelli, Brent K. Blackburn, Zhenhai Gao
  • Patent number: 7582617
    Abstract: The present invention provides a method for using the partial adenosine A2A receptor agonists having the following structure in myocardiological perfusion imaging.
    Type: Grant
    Filed: March 2, 2005
    Date of Patent: September 1, 2009
    Assignee: CV Therapeutics, Inc.
    Inventors: Luiz Belardinelli, Brent K. Blackburn, Zhenhai Gao
  • Publication number: 20070123546
    Abstract: Disclosed are 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Disclosed also are methods of using the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative, viral, autoimmune, cardiovascular, and central nervous system diseases.
    Type: Application
    Filed: September 28, 2006
    Publication date: May 31, 2007
    Inventors: Timothy Machajewski, Cynthia Shafer, Christopher McBride, William Antonios-McCrea, Brandon Doughan, Barry Levine, Yi Xia, Maureen McKeena, X. Wang, Kris Mendenhall, Yasheen Zhou, Baoquing Gong, Dan Gu, John Dolan, John Tulinsky, Kristin Brinner, Zhenhai Gao
  • Publication number: 20070027150
    Abstract: 2-Amino-quinazolin-5-one compounds, stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-quinazolin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the 2-amino-quinazolin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cell proliferative diseases.
    Type: Application
    Filed: April 14, 2006
    Publication date: February 1, 2007
    Inventors: Cornelia Bellamacina, Abran Costales, Brandon Doughan, Susan Fong, Zhenhai Gao, Thomas Hendrickson, Barry Levine, Xiaodong Lin, Timothy Machajewski, Christopher McBride, William Antonios-McCrea, Maureen McKenna, Kris Mendenhall, Alice Rico, Cynthia Shafer, X. Wang, Yi Xia, Yasheen Zhou
  • Publication number: 20050175535
    Abstract: The present invention provides a method for identifying and using partial adenosine A2A receptor agonists that are useful as adjuncts in myocardiological perfusion imaging.
    Type: Application
    Filed: March 2, 2005
    Publication date: August 11, 2005
    Inventors: Luiz Belardinelli, Brent Blackburn, Zhenhai Gao
  • Publication number: 20040137533
    Abstract: The present invention provides a method for identifying and using partial adenosine A2A receptor agonists that are useful as adjuncts in myocardiological perfusion imaging.
    Type: Application
    Filed: July 2, 2003
    Publication date: July 15, 2004
    Applicant: CV Therapeutics, Inc.
    Inventors: Luiz Belardinelli, Brent K. Blackburn, Zhenhai Gao
  • Patent number: 6576620
    Abstract: The present invention provides a method for identifying partial adenosine A1 receptor agonists that are useful in the treatment of arrhythmias. Partial adenosine A1 receptor agonists and methods for using partial adenosine A1 receptor agonists to treat arrhythmias in mammals.
    Type: Grant
    Filed: December 1, 2000
    Date of Patent: June 10, 2003
    Assignee: CV Therapeutics, Inc.
    Inventors: Luiz Belardinelli, Zhenhai Gao
  • Publication number: 20020012946
    Abstract: The present invention provides a method for identifying and using partial adenosine A2A receptor agonists that are useful as adjuncts in myocardiological perfusion imaging.
    Type: Application
    Filed: February 23, 2001
    Publication date: January 31, 2002
    Inventors: Luiz Belardinelli, Brent K. Blackburn, Zhenhai Gao
  • Publication number: 20010008883
    Abstract: The present invention provides a method for identifying parital adenosine A1 receptor agonists that are useful in the treatment of arrhythmias. Partial adenosine A1 receptor agonists and methods for using partial adenosine A1 receptor agonists to treat arrhythmias in mammals.
    Type: Application
    Filed: December 1, 2000
    Publication date: July 19, 2001
    Inventors: Luiz Belardinelli, Zhenhai Gao