Patents by Inventor Zhenjuan SHI

Zhenjuan SHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240287045
    Abstract: The present invention relates to the field of chemical pharmacy, relates to a crystal form of a pyrimidine derivative and a preparation method therefor, and specifically relates to crystal forms A, B, C, D, and E of a compound of formula (I), a preparation method therefor, and a pharmaceutical composition and use thereof. The present invention solves the problems of small granularity, poor fluidity, poor stability and the like of the compound of formula (I) present in an amorphous form. The crystal form prepared by the present invention and the pharmaceutical composition thereof can be used for preparing a drug for treating a cancer disease.
    Type: Application
    Filed: June 21, 2022
    Publication date: August 29, 2024
    Applicant: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
    Inventors: Meiyu ZHAO, Lianwei CHEN, Na LI, Zhenjuan SHI, Jianfeng ZHENG, Di SU
  • Publication number: 20220220107
    Abstract: Crystal forms A, B, C, D, E, F, G and H of a compound represented by formula I and a preparation method therefor, as well as medical uses for the various crystal forms and advantages thereof in various aspects.
    Type: Application
    Filed: May 21, 2020
    Publication date: July 14, 2022
    Applicant: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
    Inventors: Jianfeng ZHENG, Liang ZHANG, Min ZHAO, Zhenjuan SHI, Xufei LI, Zhiqing YANG
  • Patent number: 10669302
    Abstract: Provided are a new crystal form of fludarabine phosphate, a preparation method therefor, a pharmaceutical composition containing same, and an application thereof in preparing medicine. Crystal forms I and II of the fludarabine phosphate have excellent properties in terms of solubleness, dissolution rate, chemical stability, and processing adaptability.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: June 2, 2020
    Assignee: ZHEJIANF HISUN PHARMACEUTICAL CO., LTD.
    Inventors: Zhiqing Yang, Liang Zhang, Xiangyang Zhang, Zhenjuan Shi, Di Su, Hongying Luo, Dejin Fu
  • Patent number: 10364244
    Abstract: Provided are crystal forms I, II, III and IV of a pyrroloquinoline quinone sodium salt and a preparation method thereof. Also provided are a pharmaceutical composition, a cosmetic composition, a functional food or a nutritional agent containing the above-mentioned crystal forms. The crystal forms have excellent properties in terms of solubility, crystal stability, hygroscopicity and the like.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: July 30, 2019
    Assignee: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
    Inventors: Zhiqing Yang, Liang Zhang, Xiangyang Zhang, Zhenjuan Shi, Min Zhao, Hongying Luo
  • Publication number: 20190218210
    Abstract: Provided are crystal forms I, II, III and IV of a pyrroloquinoline quinone sodium salt and a preparation method thereof. Also provided are a pharmaceutical composition, a cosmetic composition, a functional food or a nutritional agent containing the above-mentioned crystal forms. The crystal forms have excellent properties in terms of solubility, crystal stability, hygroscopicity and the like.
    Type: Application
    Filed: September 14, 2016
    Publication date: July 18, 2019
    Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Zhiqing YANG, Liang ZHANG, Xiangyang ZHANG, Zhenjuan SHI, Min ZHAO, Hongying LUO
  • Publication number: 20190112327
    Abstract: Provided are a new crystal form of fludarabine phosphate, a preparation method therefor, a pharmaceutical composition containing same, and an application thereof in preparing medicine. Crystal forms I and II of the fludarabine phosphate have excellent properties in terms of solubleness, dissolution rate, chemical stability, and processing adaptability.
    Type: Application
    Filed: August 26, 2016
    Publication date: April 18, 2019
    Inventors: Zhiqing YANG, Liang ZHANG, Xiangyang ZHANG, Zhenjuan SHI, Di SU, Hongying LUO, Dejin FU
  • Publication number: 20180273526
    Abstract: Provided are crystal forms I, II, III and IV of a pyrroloquinoline quinone sodium salt and a preparation method thereof. Also provided are a pharmaceutical composition, a cosmetic composition, a functional food or a nutritional agent containing the above-mentioned crystal forms. The crystal forms have excellent properties in terms of solubility, crystal stability, hygroscopicity and the like.
    Type: Application
    Filed: September 14, 2016
    Publication date: September 27, 2018
    Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Zhiqing YANG, Liang ZHANG, Xiangyang ZHANG, Zhenjuan SHI, Min ZHAO, Hongying LUO
  • Publication number: 20180244711
    Abstract: Provided are a new crystal form of fludarabine phosphate, a preparation method therefor, a pharmaceutical composition containing same, and an application thereof in preparing medicine. Crystal forms I and II of the fludarabine phosphate have excellent properties in terms of solubleness, dissolution rate, chemical stability, and processing adaptability.
    Type: Application
    Filed: August 26, 2016
    Publication date: August 30, 2018
    Inventors: Zhiqing YANG, Liang ZHANG, Xiangyang ZHANG, Zhenjuan SHI, Di SU, Hongying LUO, Dejin FU