Patents by Inventor Zhenkun Ma

Zhenkun Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrolide antibacterial compounds
    Publication number: 20040014687
    Abstract: Macrolide antibacterial compounds having formula (I) 1
    Type: Application
    Filed: April 22, 2003
    Publication date: January 22, 2004
    Inventors: Zhenkun Ma, Stevan Djuric
  • 9-Oxime macrolide antibacterials
    Publication number: 20040014691
    Abstract: Antibacterial compounds having formula (I) 1
    Type: Application
    Filed: April 22, 2003
    Publication date: January 22, 2004
    Inventors: Xenia Beebe Searle, Stevan Djuric, Zhenkun Ma, Fan Yang
  • Macrolides with activity against methicillin-resistant staphylococcus aureus
    Publication number: 20040014690
    Abstract: Compounds having activity against methicillin-resistant staphylococcus aureus (MRSA), the compounds having formula (I) 1
    Type: Application
    Filed: February 10, 2003
    Publication date: January 22, 2004
    Inventors: Zhenkun Ma, Stevan Djuric, Robert Keyes, Hong Yong
  • Macrolide antibacterial compounds
    Publication number: 20040009931
    Abstract: Antibacterial compounds having formula (I) 1
    Type: Application
    Filed: February 10, 2003
    Publication date: January 15, 2004
    Inventors: Richard Clark, Stevan Djuric, Zhenkun Ma, Sanyi Wang
  • Antibacterial compounds with activity against penicillin-resistant streptococcus pneumoniae
    Publication number: 20040009932
    Abstract: Compounds which are useful as antibacterials for penicillin-resistant streptococcus pneumoniae and having formula (I) 1
    Type: Application
    Filed: April 23, 2003
    Publication date: January 15, 2004
    Inventors: Kathleen Phelan, Stevan Djuric, Zhenkun Ma, Thomas Marron, Hong Yong, Irini Zanze
  • 9-amino erythromycin derivatives with antibacterial activity
    Patent number: 6667338
    Abstract: Compounds of formula (I) and formula (II) or therapeutically acceptable salts or prodrugs thereof are useful as antibacterial agents. Methods to make the compounds, compositions containing the compounds, and methods of treatment using the compounds are also disclosed.
    Type: Grant
    Filed: January 16, 2002
    Date of Patent: December 23, 2003
    Assignee: Abbott Laboratories
    Inventors: Zhenkun Ma, Ly Tam Phan, Suoming Zhang, Stevan W. Djuric
  • Antibacterial compounds
    Publication number: 20030232818
    Abstract: Antibacterials having formula (I) 1
    Type: Application
    Filed: March 12, 2003
    Publication date: December 18, 2003
    Inventors: David Anderson, Bruce Beutel, Todd D. Bosse, Richard Clark, Curt Cooper, Peter Dandliker, Caroline David, Yu-Gui Gu, Todd Matthew Hansen, Mira Hinman, Douglas Kalvin, Daniel P. Larson, Linda Lynch, Zhenkun Ma, Christopher Motter, Fabio Palazzo, Teresa Rosenberg, Tamara Rehm, William Sanders, Michael Tufano, Rolf Wagner, Moshe Weitzberg, Hong Yong, Tianyuan Zhang
  • Antibacterial compounds with improved pharmacokinetic profiles
    Publication number: 20030207820
    Abstract: Antibacterial compounds with improved pharmacokinetic profiles having formula (I) 1
    Type: Application
    Filed: April 30, 2002
    Publication date: November 6, 2003
    Inventors: Richard F. Clark, Stevan Djuric, Zhenkun Ma, Ly Phan, Michael Rupp
  • Macrolide antibacterial compounds
    Publication number: 20030171308
    Abstract: Antibacterial compounds having formula (I) 1
    Type: Application
    Filed: February 13, 2002
    Publication date: September 11, 2003
    Inventors: Richard Clark, Stevan Djuric, Zhenkun Ma, Sanyi Wang
  • Macrolides with activity against methicillin-resistant staphylococcus aureus
    Publication number: 20030162729
    Abstract: Compounds having activity against methicillin-resistant staphylococcus aureus (MRSA), the compounds having formula (I) 1
    Type: Application
    Filed: February 13, 2002
    Publication date: August 28, 2003
    Inventors: Zhenkun Ma, Stevan Djuric, Robert Keyes, Hong Yong
  • 6-O-alkyl-2-nor-2-substituted ketolide derivatives
    Patent number: 6569836
    Abstract: The present invention relates to 6-O-alkyl-2-nor-2-substituted ketolide compound or a derivative thereof, a composition comprising the compound and a suitable carrier, a method of preparing the compound, and a method of treatment and prevention of in mammals comprising administering said compound.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: May 27, 2003
    Assignee: Abbott Laboratories
    Inventors: Ly Tam Phan, Yat Sun Or, Zhenkun Ma
  • C-2 modified erythromycin derivatives
    Publication number: 20020193320
    Abstract: A compound having the formula selected from the group consisting of 1
    Type: Application
    Filed: May 3, 2000
    Publication date: December 19, 2002
    Inventors: Zhenkun Ma, Yat Sun Or, Ly Tam Phan, Suoming Zhang, Richard F. Clark
  • 9-Amino erythromycin derivatives with antibacterial activity
    Publication number: 20020142973
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: January 16, 2002
    Publication date: October 3, 2002
    Inventors: Zhenkun Ma, Ly Tam Phan, Suoming Zhang, Stevan W. Djuric
  • 9-amino erythromycin derivatives with antibacterial activity
    Publication number: 20020132782
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: January 18, 2001
    Publication date: September 19, 2002
    Inventors: Zhenkun Ma, Ly Tam Phan, Suoming Zhang, Stevan Djuric
  • 6-O-alkyl-2-nor-2-substituted ketolide derivatives
    Publication number: 20020103140
    Abstract: The present invention relates to 6-O-alkyl-2-nor-2-substituted ketolide compound or a derivative thereof, a composition comprising the compound and a suitable carrier, a method of preparing the compound, and a method of treatment and prevention of in mammals comprising administering said compound.
    Type: Application
    Filed: November 30, 2000
    Publication date: August 1, 2002
    Inventors: Ly Tam Phan, Yat Sun Or, Zhenkun Ma
  • 6-O-carbamate ketolide derivatives
    Patent number: 6420535
    Abstract: The invention relates to a novel 6-O-carbamate ketolide compound or a pharmaceutically acceptable salt, ester, solvate or prodrug thereof, to a composition comprising the compound and a suitable carrier, a method of preparing the compound, and a method of treatment and prevention of infections in a mammal.
    Type: Grant
    Filed: May 24, 2000
    Date of Patent: July 16, 2002
    Assignee: Abbott Laboratories
    Inventors: Ly Tam Phan, Yat Sun Or, Zhenkun Ma, Yan Chen
  • C-2 modified erythromycin derivatives
    Patent number: 6355620
    Abstract: A compound having the formula selected from the group consisting of a compound of formula I a compound of formula II a compound of formula III as well as and pharmaceutically acceptable salts, esters, solvates, metabolites, and prodrugs thereof, are useful in treating bacterial infections. Also provided are pharmaceutically acceptible compositions, methods of treating bacterial infections, and processes for the preparation of the compounds.
    Type: Grant
    Filed: May 14, 1999
    Date of Patent: March 12, 2002
    Assignee: Abbott Laboratories
    Inventors: Zhenkun Ma, Yat Sun Or, Ly Tam Phan, Suoming Zhang, Richard F. Clark
  • Anti-infective agents useful against multidrug-resistant strains of bacteria
    Publication number: 20020019355
    Abstract: The invention relates to novel methods for using macrolide anti-infective agents. The macrolide anti-infective agents demonstrate antibacterial activity against multi-drug resistant strains of bacteria and, in particular, methicillin-resistant Staphylococcus aureus (MRSA). Methods for inhibiting the activity of multi-drug resistant bacterial organisms and methods for treating a bacterial infection caused by such organisms are described herein.
    Type: Application
    Filed: February 23, 2001
    Publication date: February 14, 2002
    Inventors: Zhenkun Ma, Peter Nemoto, Suoming Zhang, Hong Yong, Yat Sun Or
  • 6-O-substituted erythromycin ketolides having antibacterial activity
    Patent number: 6147197
    Abstract: Antimicrobial compounds having the formula ##STR1## as well as pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.
    Type: Grant
    Filed: November 4, 1998
    Date of Patent: November 14, 2000
    Inventors: Yat Sun Or, Zhenkun Ma, Richard F. Clark, Daniel T. Chu, Jacob J. Plattner, George Griesgraber
  • 6-O-substituted erythromycin compounds and method for making same
    Patent number: 6075011
    Abstract: Antimicrobial compounds having the formula ##STR1## as well as the pharmaceutically acceptable salts, esters and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.
    Type: Grant
    Filed: April 29, 1997
    Date of Patent: June 13, 2000
    Assignee: Abbott Laboratories
    Inventors: Yat Sun Or, Richard F. Clark, Zhenkun Ma, George Griesgraber, Leping Li, Daniel T. Chu