Patents by Inventor Zhenliang Chen

Zhenliang Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200254273
    Abstract: A method, apparatus and components thereof enable stimulating synthesis of new collagen and elastic fibers in superficial tissues, of a human or other living subject by introducing magnetic particles into the superficial tissue and activating the magnetic particles by application of magnetic field to stimulate synthesis of new collagen and elastic fibers.
    Type: Application
    Filed: February 7, 2020
    Publication date: August 13, 2020
    Inventors: Sahar JAFARI, Irving WEINBERG, Ann XIN, Richard CAO, Zhenliang Chen, Elaine Yi WANG
  • Patent number: 10265821
    Abstract: An automatic component loading system is disclosed. The automatic component loading system has a loading device, a conveying device having a plurality of first pin receiving slots and a plurality of first component receiving trays positioned around a circumference of the conveying device, and a position correcting device having at least one pin that corresponds with the plurality of first pin receiving slots.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: April 23, 2019
    Assignees: Tyco Electronics (Shanghai) Co. Ltd., Tyco Electronics (Shenzhen) Co. Ltd., Shenzhen AMI Technology Co., Ltd
    Inventors: Yingcong Deng, Dandan Zhang, Roberto Francisco-Yi Lu, Yaodong Wu, Zhenliang Chen, Zhao Li, Jin Su, Zhi Li, Qinglong Zeng
  • Patent number: 9872903
    Abstract: A targeting thymidine kinase photosensitizer and pharmaceutical composition and use for cancer treatment thereof is provided, which improves the selectivity of photosensitizers to tumor cells, has better tolerance, can reach maximum blood concentration in 24 hours, has a bigger conjugated system, a longer absorption wavelength and an advantage in treating depth tumors; the wavelength area does not need to consume much energy of a light-output device and even LEDs can be used, which render PDT more practical and economical. The targeting thymidine kinase photosensitizer can be used for diagnosis and for treating prostatic carcinoma via the guidance of fluorescence imaging. The pharmaceutical composition uses a combination of a chemotherapeutic agent and the targeting thymidine kinase photosensitizer, which further improves the therapeutic effect of the PDT method, expands the application range for tumors and has good effects on metastatic tumors as well.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: January 23, 2018
    Assignee: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD
    Inventors: Ravindra K Pandey, Yihui Chen, Hua Bai, Zhenliang Chen
  • Patent number: 9821062
    Abstract: Disclosed are a cyanine dye compound and a preparation method therefor, and a dual-function agent for photodynamic therapy and a preparation method therefor. The provided cyanine dye compound is connected to multiple markers, which improves the accuracy of combination of dye and tumor cells, effectively reduces the background value, and avoids excessive residues in the liver. The provided cyanine dye compound is conjugated with the photosensitizer at 2?? position, so that tumor highly absorbs the conjugates.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: November 21, 2017
    Assignee: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
    Inventors: Ravindra K. Pandey, Nayan Patel, Manivannan Ethirajan, Hua Bai, Zhenliang Chen
  • Publication number: 20160151494
    Abstract: A targeting thymidine kinase photosensitizer and pharmaceutical composition and use for cancer treatment thereof is provided, which improves the selectivity of photosensitizers to tumor cells, has better tolerance, can reach maximum blood concentration in 24 hours, has a bigger conjugated system, a longer absorption wavelength and an advantage in treating depth tumors; the wavelength area does not need to consume much energy of a light-output device and even LEDs can be used, which render PDT more practical and economical. The targeting thymidine kinase photosensitizer can be used for diagnosis and for treating prostatic carcinoma via the guidance of fluorescence imaging. The pharmaceutical composition uses a combination of a chemotherapeutic agent and the targeting thymidine kinase photosensitizer, which further improves the therapeutic effect of the PDT method, expands the application range for tumors and has good effects on metastatic tumors as well.
    Type: Application
    Filed: November 2, 2012
    Publication date: June 2, 2016
    Inventors: RAVINDRA K PANDEY, YIHUI CHEN, HUA BAI, ZHENLIANG CHEN
  • Publication number: 20160128243
    Abstract: An automatic component loading system is disclosed. The automatic component loading system has a loading device, a conveying device having a plurality of first pin receiving slots and a plurality of first component receiving trays positioned around a circumference of the conveying device, and a position correcting device having at least one pin that corresponds with the plurality of first pin receiving slots.
    Type: Application
    Filed: October 30, 2015
    Publication date: May 5, 2016
    Applicants: Tyco Electronics (Shanghai) Co. Ltd., Tyco Electronics (Shenzhen) Co. Ltd, Shenzhen AMI Technology Co., Ltd
    Inventors: Yingcong Deng, Dandan Zhang, Roberto Francisco-Yi Lu, Yaodong Wu, Zhenliang Chen, Zhao Li, Jin Su, Zhi Li, Qinglong Zeng
  • Patent number: 9260444
    Abstract: The present invention provides a crystalline form of HPPH (2-((1?-n-hexyloxy)ethyl)-2-divinyl-pyropheophorbide-a): The crystalline form can be characterized by an X-ray powder diffraction (XRD) pattern and differential scanning calorimeter (DSC) pattern. The present invention also provides a method for preparing the crystalline form of HPPH.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: February 16, 2016
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Zhenliang Chen, Fei Zheng, Yumei Wu, Tianmin Zhu, Hua Bai
  • Publication number: 20150329490
    Abstract: Disclosed are a cyanine dye compound and a preparation method therefor, and a dual-function agent for photodynamic therapy and a preparation method therefor. The provided cyanine dye compound is connected to multiple markers, which improves the accuracy of combination of dye and tumor cells, effectively reduces the background value, and avoids excessive residues in the liver. The provided cyanine dye compound is conjugated with the photosensitizer at 2?? position, so that tumor highly absorbs the conjugates.
    Type: Application
    Filed: February 6, 2013
    Publication date: November 19, 2015
    Inventors: Ravindra K. PANDEY, Hua BAI, Manivannan ETHIRAJAN, Nayan PATEL, Zhenliang CHEN
  • Publication number: 20150099873
    Abstract: The present invention provides a crystalline form of HPPH (2-((1?-n-hexyloxy)ethyl)-2-divinyl-pyropheophorbide-a). The crystalline form can be characterized by an X-ray powder diffraction (XRD) pattern and differential scanning calorimeter (DSC) pattern. The present invention also provides a method for preparing the crystalline form of HPPH.
    Type: Application
    Filed: February 7, 2013
    Publication date: April 9, 2015
    Inventors: Zhenliang Chen, Fei Zheng, Yumei Wu, Tianmin Zhu, Hua Bai
  • Patent number: 8822519
    Abstract: The present invention provides a novel compound of formula I, which has an agitation effect on the peroxisome proliferator-activated receptor subtype ? (PPAR?), to a pharmaceutical composition comprising the compound, to a process for preparation of the compound and to use of the compound in the manufacture of a medicament for treating or preventing a disease which could be treated or prevented by activating PPAR? thereof, said disease is one or more from the group comprising metabolic syndrome, obesity, dyslipidemia, pathoglycemia, insulin resistance, senile dementia and tumors. The present invention also relates to a new intermediate used in the preparation of the novel compound and a process for preparation of the intermediate.
    Type: Grant
    Filed: August 7, 2009
    Date of Patent: September 2, 2014
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Chunhua Jin, Xiaoyu Liu, Zhenliang Chen, Xiaohe Zheng, Shoufeng Ming
  • Publication number: 20110319458
    Abstract: The present invention provides a novel compound of formula I, which has an agitation effect on the peroxisome proliferator-activated receptor subtype ? (PPAR?), to a pharmaceutical composition comprising the compound, to a process for preparation of the compound and to use of the compound in the manufacture of a medicament for treating or preventing a disease which could be treated or prevented by activating PPAR? thereof, said disease is one or more from the group comprising metabolic syndrome, obesity, dyslipidemia, pathoglycemia, insulin resistance, senile dementia and tumors. The present invention also relates to a new intermediate used in the preparation of the novel compound and a process for preparation of the intermediate.
    Type: Application
    Filed: August 7, 2009
    Publication date: December 29, 2011
    Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Chunhua Jin, Xiaoyu Liu, Zhenliang Chen, Xiaohe Zheng, Shoufeng Ming