Patents by Inventor Zhenlong YE

Zhenlong YE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Killer cell capable of efficiently and stably expressing antibody, and uses thereof
    Patent number: 12042515
    Abstract: Provided is a transgenic killer cell, the genome of which is stably integrated with a coding sequence comprising an antibody of a human Fc section, or an expression cassette of a coding sequence comprising a chimeric antigen receptor or an inhibitory or agonistic antibody, and an inverted terminal repeat sequence from a transposon at both ends. Also provided is a pharmaceutical composition comprising the transgenic killer cell, and uses thereof.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: July 23, 2024
    Assignees: Shanghai Cell Therapy Research Institute, Shanghai Cell Therapy Group Co., Ltd.
    Inventors: Qijun Qian, Huajun Jin, Jieying Xu, Linfang Li, Zhenlong Ye, Zhou He, Lianzhen Cui, Hongping Wu
  • KILLER CELL CAPABLE OF EFFICIENTLY AND STABLY EXPRESSING ANTIBODY, AND USES THEREOF
    Publication number: 20200289561
    Abstract: Provided is a transgenic killer cell, the genome of which is stably integrated with a coding sequence comprising an antibody of a human Fc section, or an expression cassette of a coding sequence comprising a chimeric antigen receptor or an inhibitory or agonistic antibody, and an inverted terminal repeat sequence from a transposon at both ends. Also provided is a pharmaceutical composition comprising the transgenic killer cell, and uses thereof.
    Type: Application
    Filed: June 19, 2017
    Publication date: September 17, 2020
    Inventors: Qijun QIAN, Huajun JIN, Jieying XU, Linfang LI, Zhenlong YE, Zhou HE, Lianzhen CUI, Hongping WU