Patents by Inventor Zhenming JIN

Zhenming JIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230302019
    Abstract: Disclosed is compound YM155, tanshinone I or cryptotanshinone, or a pharmaceutically acceptable salt thereof, a solvate thereof, a solvate of the pharmaceutically acceptable salt thereof, or a crystal form thereof; for treating and/or preventing diseases caused by coronavirus.
    Type: Application
    Filed: April 29, 2021
    Publication date: September 28, 2023
    Inventors: Haitao YANG, Zhenming JIN, Xiaoyu DU, Yinkai DUAN, Yao ZHAO, Xiuna YANG, Zihe RAO
  • Publication number: 20230293457
    Abstract: An application of disulfiram in coronavirus resistance. An application of disulfiram in the preparation of drugs for treating and/or preventing diseases caused by coronaviruses. By means of in vitro enzyme activity experiments, it is found that disulfiram can well inhibit the activity of the main protease in coronaviruses, filling in the lack in the prior art to treat diseases caused by coronaviruses.
    Type: Application
    Filed: February 26, 2021
    Publication date: September 21, 2023
    Inventors: Haitao YANG, Zhenming JIN, Xiuna YANG, Yao ZHAO, Zihe RAO
  • Publication number: 20230138310
    Abstract: Use of an aldehyde-based compound as represented by general formula I, a pharmaceutical composition, a pharmaceutical salt, an enantiomer, a diastereomer and a racemic compound thereof as a novel coronavirus 2019 (2019-nCov) 3CL protease inhibitor in preparation of a medicament for treating and/or preventing and relieving respiratory tract infections, pneumonia and other related diseases caused by the novel coronavirus infection 2019.
    Type: Application
    Filed: March 26, 2020
    Publication date: May 4, 2023
    Inventors: Hong LIU, Jian LI, Wenhao DAI, Jingjing PENG, Xiong XIE, Shulei HU, Chunpu LI, Yechun XU, Haitao YANG, Leike ZHANG, Haixia SU, Hualiang JIANG, Zhenming JIN, Gengfu XIAO, Kaixian CHEN
  • Publication number: 20230133600
    Abstract: A class of ketoamide-based compounds, in particular, a ketoarnide-based compound as represented by general formula A is provided. The ketoamide compound may be used as a 2019 novel coronavirus (2019-nCov) 3 CL protease inhibitor and/or human cathepsin L inhibitor, and/or may be used in the preparation of a medicament for treating and/or preventing and relieving respiratory tract infection, pneumonia and other related diseases caused by 2019 novel coronavirus infection. Pharmaceutical compositions of the class of compounds, pharmaceutical salts, enantiomeric forms, diastereoisomers and racemic compounds thereof in the preparation of a medicament for treating and/or preventing and relieving respiratory tract infections and other related diseases caused by the 2019 novel coronavirus infection are also provided.
    Type: Application
    Filed: January 28, 2021
    Publication date: May 4, 2023
    Inventors: Hong LIU, Jian LI, Jingjing PENG, Xiong XIE, Wenhao DAI, Shulei HU, Chunpu LI, Leike ZHANG, Zhenming JIN, Yechun XU, Gengfu XIAO, Haitao YANG, Fang BAI, Xi CHENG, Hualiang JIANG, Kaixian CHEN
  • Patent number: 11464765
    Abstract: Disclosed is a use of an N-substituted pyridyl benzisoselazolone compound. The use is particularly a use in the preparation of a medicament for treating and/or preventing a disease caused by coronavirus. The present disclosure surprisingly found that the N-substituted pyridyl benzisoselazolone compound, such as ebselen, can significantly inhibit the activity of the main protease of a coronavirus and the intracellular replication capability of SARS-CoV-2, which can be used for treating a disease caused by coronavirus.
    Type: Grant
    Filed: August 13, 2021
    Date of Patent: October 11, 2022
    Assignee: SHANGHAITECH UNIVERSITY
    Inventors: Haitao Yang, Zhenming Jin, Xiuna Yang, Yao Zhao, Zihe Rao
  • Publication number: 20210369696
    Abstract: Disclosed is a use of an N-substituted pyridyl benzisoselazolone compound. The use is particularly a use in the preparation of a medicament for treating and/or preventing a disease caused by coronavirus. The present disclosure surprisingly found that the N-substituted pyridyl benzisoselazolone compound, such as ebselen, can significantly inhibit the activity of the main protease of a coronavirus and the intracellular replication capability of SARS-CoV-2, which can be used for treating a disease caused by coronavirus.
    Type: Application
    Filed: August 13, 2021
    Publication date: December 2, 2021
    Inventors: Haitao YANG, Zhenming JIN, Xiuna YANG, Yao ZHAO, Zihe RAO