Patents by Inventor Zhenping Huang

Zhenping Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticle formulations of decoquinate in the form of solid solution
    Patent number: 11602532
    Abstract: Hot-melt extrusion for producing solid solution comprising nanoparticle formulation of decoquinate is disclosed. Aqueous phase comprising the nanoparticles of hot-melt extruding products is homogeneous and stable. Provided is the composition comprising the solid solution of decoquinate and a method of hot-melt extrusion for producing this composition comprising the solid dispersion of decoquinate. Furthermore, provided is the solid solution comprising nanosized decoquinate formulation having improved water solubility and enhanced delivery of decoquinate in digestive system for absorption, increasing bioavailability, and the efficacy against malaria at the liver stage.
    Type: Grant
    Filed: January 2, 2019
    Date of Patent: March 14, 2023
    Assignee: CAS Lamvac (Guangzhou) Biomedical Technology Co., Ltd.
    Inventors: Hongxing Wang, Shuanghong Liang, Yinzhou Fan, Zhenping Huang, Siting Zhao, Li Qin, Xiaoping Chen
  • NANOPARTICLE FORMULATIONS OF DECOQUINATE IN THE FORM OF SOLID SOLUTION
    Publication number: 20210077480
    Abstract: Hot-melt extrusion for producing solid solution comprising nanoparticle formulation of decoquinate is disclosed. Aqueous phase comprising the nanoparticles of hot-melt extruding products is homogeneous and stable. Provided is the composition comprising the solid solution of decoquinate and a method of hot-melt extrusion for producing this composition comprising the solid dispersion of decoquinate. Furthermore, provided is the solid solution comprising nanosized decoquinate formulation having improved water solubility and enhanced delivery of decoquinate in digestive system for absorption, increasing bioavailability, and the efficacy against malaria at the liver stage.
    Type: Application
    Filed: January 2, 2019
    Publication date: March 18, 2021
    Inventors: Hongxing Wang, Shuanghong Liang, Yinzhou Fan, Zhenping Huang, Siting Zhao, Li Qin, Xiaoping Chen