Patents by Inventor Zhenqian Liu

Zhenqian Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIV DNA vaccine methods of use
    Patent number: 8785411
    Abstract: The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for use as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3? LTR.
    Type: Grant
    Filed: July 18, 2011
    Date of Patent: July 22, 2014
    Assignee: University of Kansas Medical Center
    Inventor: Zhenqian Liu
  • DNA vaccine compositions with HIV/SIV gene modifications
    Patent number: 8765140
    Abstract: The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for use as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3? LTR.
    Type: Grant
    Filed: July 18, 2011
    Date of Patent: July 1, 2014
    Assignee: University of Kansas Medical Center
    Inventor: Zhenqian Liu
  • HIV DNA Vaccine Methods of Use
    Publication number: 20120021000
    Abstract: The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for use as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3? LTR.
    Type: Application
    Filed: July 18, 2011
    Publication date: January 26, 2012
    Applicant: UNIVERSITY OF KANSAS MEDICAL CENTER
    Inventors: Opendra Narayan, Zhenqian Liu
  • DNA Vaccine Compositions with HIV/SIV Gene Modifications
    Publication number: 20120020999
    Abstract: The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for use as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3? LTR.
    Type: Application
    Filed: July 18, 2011
    Publication date: January 26, 2012
    Applicant: UNIVERSITY OF KANSAS MEDICAL CENTER
    Inventors: Opendra Narayan, Zhenqian Liu
  • DNA vaccine compositions and methods of use
    Patent number: 8003113
    Abstract: The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for used as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3? LTR.
    Type: Grant
    Filed: February 9, 2009
    Date of Patent: August 23, 2011
    Inventors: Opendra Narayan, Zhenqian Liu
  • DNA VACCINE COMPOSITIONS AND METHODS OF USE
    Publication number: 20090233857
    Abstract: The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for used as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3? LTR.
    Type: Application
    Filed: February 9, 2009
    Publication date: September 17, 2009
    Applicant: University of Kansas Medical Center
    Inventors: Opendra Narayan, Zhenqian Liu
  • DNA vaccine compositions and methods of use
    Patent number: 7488485
    Abstract: The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for use as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3? LTR.
    Type: Grant
    Filed: September 15, 2004
    Date of Patent: February 10, 2009
    Assignee: University of Kansas Medical Center
    Inventors: Opendra Narayan, Zhenqian Liu
  • DNA vaccine compositions and methods of use
    Publication number: 20050112102
    Abstract: The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for use as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3? LTR.
    Type: Application
    Filed: September 15, 2004
    Publication date: May 26, 2005
    Inventors: Opendra Narayan, Zhenqian Liu