Patents by Inventor Zhenrong Guo

Zhenrong Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240118157
    Abstract: An ambient pressure compensation structure for an ultraviolet difference spectrum gas sensor includes a closed box, an ultraviolet difference spectrum gas sensor, a digital pressure sensor, a thermostatic controller, an industrial control computer, a pressure regulating assembly and a limiting partition; the pressure regulating assembly and the limiting partition are arranged inside the closed box, the pressure regulating assembly comprises a piston, a regulating rod and a driving motor, the left side of the piston is connected with the regulating rod, the front end of the regulating rod penetrates out of the closed box and is connected with the driving motor, and the piston divides the interior of the closed box into a pressure regulating air chamber and a working air chamber. Also disclosed is an ambient pressure compensation method for an ultraviolet difference spectrum gas sensor.
    Type: Application
    Filed: December 19, 2023
    Publication date: April 11, 2024
    Inventors: Fuchao TIAN, Yuntao LIANG, Shuanglin SONG, Xing AI, Yazhou XU, Weiwei SU, Baolong GUO, Zhenrong LI
  • Publication number: 20140161996
    Abstract: A method of imaging acrylic glass is presented. An image is formed on a transfer sheet or medium, and is heat transferred to the acrylic glass substrate on which the image is to permanently appear. An opaque pass-through coating is applied to one surface of the clear or transparent acrylic glass article. Heat activatable dye forms the image, and the heat activatable dye, when heat activated in close relationship to the opaque pass-through coating, passes through the opaque pass-through coating to the acrylic glass substrate. The image reflects light through the acrylic glass and is visible through the material and from the side opposite the opaque coating. The opaque pass-through coating layer permanently bonds to the acrylic glass surface.
    Type: Application
    Filed: July 25, 2013
    Publication date: June 12, 2014
    Inventors: Ming Xu, Zhenrong Guo, Sukun Zhang, Paul Hirst
  • Patent number: 8029883
    Abstract: A transfer medium is provided for receiving images formed on the medium by inks or toners comprising thermally diffusible colorants, including disperse dye and sublimation dye, and methods of using the medium to present images on substrates. The medium provides an opaque layer that allows transfer of the image from the medium to a substrate, and provides a background for the image when the image is transferred to a dark colored substrate, so that the dark colored substrate does not obscure the image.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: October 4, 2011
    Inventors: Ming Xu, Zhenrong Guo, Sukun Zhang
  • Publication number: 20110111188
    Abstract: A method of imaging thermoplastics, such as acrylic glass, is presented. An image is formed on a transfer sheet or medium, and is heat transferred to the acrylic glass substrate on which the image is to permanently appear. An opaque pass-through coating is applied to one surface of the clear or transparent acrylic glass article. Heat activatable dye forms the image, and the heat activatable dye, when heat activated in close relationship to the opaque pass-through coating, passes through the opaque pass-through coating to the thermoplastic substrate. The image reflects light through the thermoplastic material and is visible through the material and from the side opposite the opaque coating. The opaque pass-through coating layer permanently bonds to the acrylic glass surface.
    Type: Application
    Filed: November 11, 2010
    Publication date: May 12, 2011
    Inventors: Ming Xu, Zhenrong Guo, Sukun Zhang, Paul Hirst
  • Publication number: 20100129572
    Abstract: A transfer medium is provided for receiving images formed on the medium by inks or toners comprising thermally diffusible colorants, including disperse dye and sublimation dye, and methods of using the medium to present images on substrates. The medium provides an opaque layer that allows transfer of the image from the medium to a substrate, and provides a background for the image when the image is transferred to a dark colored substrate, so that the dark colored substrate does not obscure the image.
    Type: Application
    Filed: November 5, 2009
    Publication date: May 27, 2010
    Inventors: Ming Xu, Zhenrong Guo, Sukun Zhang
  • Publication number: 20070181253
    Abstract: This invention is a process of printing or forming a resist layer over an area of a printed transfer medium that has binders or other materials thereon but is not covered by a printed image. The layer resists transfer to the final substrate of binder materials and other materials of the transfer medium that are not covered with the printed image.
    Type: Application
    Filed: April 28, 2006
    Publication date: August 9, 2007
    Inventors: Ming Xu, Sukun Zhang, Zhenrong Guo
  • Patent number: 7164015
    Abstract: The present invention provides a method for making glycoside compounds including the steps of: (a) lithiating an aromatic reactant having a leaving group using a lithium reagent in a first microreactor under non-cryogenic conditions to form a lithiated anion species, and (b) coupling the lithiated anion species with a carbonyl substituted reactant to form a glycoside.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: January 16, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Lifen Shen, San Kiang, Zhenrong Guo
  • Patent number: 7153879
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: December 26, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Publication number: 20060063815
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
    Type: Application
    Filed: November 10, 2005
    Publication date: March 23, 2006
    Inventors: John DiMarco, Jack Gougoutas, Imre Vitez, Martha Davidovich, Michael Galella, Timothy Malloy, Zhenrong Guo, Denis Favreau
  • Patent number: 6982276
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: January 3, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Publication number: 20050171140
    Abstract: Compounds are provided having the following structure and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, U, V, W, Y, and n are as defined above, which compounds are HMG CoA reductase inhibitors and thus are active in inhibiting cholesterol biosynthesis, modulating blood serum lipids, for example, lowering LDL cholesterol and/or increasing HDL cholesterol, and treating hyperlipidemia, dyslipidemia, hypercholesterolemia, hypertriglyceridemia and atherosclerosis as well as Alzheimer's disease and osteoporosis and may be employed as hormone replacement therapy. A method for treating the above diseases employing the above compounds is also provided.
    Type: Application
    Filed: November 15, 2004
    Publication date: August 4, 2005
    Inventors: Stephen O'Connor, Jeffrey Robl, Saleem Ahmad, Sharon Bisaha, Natesan Murugesan, Khehyong Ngu, Yan Shi, Philip Stein, Nachimuthu Soundararajan, Kenneth Natalie, Laxma Kolla, Justin Sausker, Sandra Quinlan, Junying Fan, Dejah Petsch, Zhenrong Guo
  • Publication number: 20040230045
    Abstract: The present invention provides a method for making glycoside compounds including the steps of: (a) lithiating an aromatic reactant having a leaving group using a lithium reagent in a first microreactor under non-cryogenic conditions to form a lithiated anion species, and (b) coupling the lithiated anion species with a carbonyl substituted reactant to form a glycoside.
    Type: Application
    Filed: February 27, 2004
    Publication date: November 18, 2004
    Inventors: Lifen Shen, San Kiang, Zhenrong Guo
  • Publication number: 20040157897
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula 1
    Type: Application
    Filed: February 6, 2004
    Publication date: August 12, 2004
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Patent number: 6689802
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: February 10, 2004
    Assignee: Bristol-Myers Squibb Company
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Patent number: 6518421
    Abstract: The present invention relates to a process for the preparation of epothilone analogs by initially forming novel ring-opened epothilones and carrying out a macrolactamization reaction thereon. The subject process is amenable to being carried out in a single reaction vessel without isolation of the intermediate compound and provides at least about a three-fold increase in yield over prior processes for preparing the desired epothilone analogs.
    Type: Grant
    Filed: February 1, 2001
    Date of Patent: February 11, 2003
    Assignee: Bristol-Myers Squibb Company
    Inventors: Wen Sen Li, John E. Thornton, Zhenrong Guo, Shankar Swaminathan
  • Publication number: 20030004338
    Abstract: The present invention relates to a process for the preparation of epothilone analogs by initially forming novel ring-opened epothilones and carrying out a macrolactamization reaction thereon. The subject process is amenable to being carried out in a single reaction vessel without isolation of the intermediate compound and provides at least about a three-fold increase in yield over prior processes for preparing the desired epothilone analogs.
    Type: Application
    Filed: September 5, 2001
    Publication date: January 2, 2003
    Inventors: Wen Sen Li, John E. Thornton, Zhenrong Guo, Shankar Swaminathan
  • Publication number: 20020188014
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula 1
    Type: Application
    Filed: August 9, 2001
    Publication date: December 12, 2002
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Patent number: RE39251
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
    Type: Grant
    Filed: March 9, 2005
    Date of Patent: August 29, 2006
    Assignee: Bristol-Myers Squibb Co.
    Inventor: Zhenrong Guo
  • Patent number: RE39356
    Abstract: The present invention relates to a process for the preparation of epothilone analogs by initially forming novel ring-opened epothilones and carrying out a macrolactamization reaction thereon. The subject process is amenable to being carried out in a single reaction vessel without isolation of the intermediate compound and provides at least about a three-fold increase in yield over prior processes for preparing the desired epothilone analogs.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: October 17, 2006
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Wen Sen Li, John E. Thornton, Zhenrong Guo, Shankar Swaminathan, Robert M. Borzilleri, Soong-Hoon Kim, Denis Favreau