Abstract: The present invention relates to the technical field of immunotherapy and molecular immunology, in particular to an antibody against OX40 and the medical use. Provided in the present invention is a specific antibody or an antigen binding fragment thereof, which has a high affinity to OX40 and can block the interaction and signaling of OX40/OX40L.

Abstract: A high-precision multi-pole magnetoelectric encoder includes a mounting seat, a rotating shaft, a single-pole magnet ring, a single-pole signal processing board, a shielding shell, an n-pole magnet ring, an n-pole signal processing board, a housing, a conductive rubber pad, an aviation plug, bearings, copper columns, Hall components, and assembly screws. The magnetoelectric encoder improves the environmental adaptability and replaceability of the high-precision multi-pole magnetoelectric encoder by redesigning the structure of the multi-pole encoder. It eliminates errors caused by changes in the position of magnets and Hall sensors during the replacement process, reduces interference caused by the multi-pole magnet encircling the single-pole magnet, enhances resistance to electromagnetic interference, thereby increasing the detection accuracy of the magnetoelectric encoder, and improves the performance and competitiveness of the product.

Abstract: The present invention discloses a multi-channel impact-resistant intelligent-constant-deceleration hydraulic braking system, and relates to the field of safety braking control for mine hoist systems. A technical point of the braking system is that the braking system includes a braking circuit formed by a constant-deceleration hydraulic system, a constant-deceleration electrical closed-loop control system, and a detection and feedback apparatus. The constant-deceleration hydraulic system is provided with N+1 independent complete oil return channels, where N is a positive integer greater than or equal to 3. The oil return channels are disposed in parallel to form parallel independent braking circuits, that is, are “multi-channel” and do not have a “common output point”. The oil return channel includes a backup oil source, an electro-hydraulic signal conversion and amplification component, an operating mode switching apparatus, and an execution component that are sequentially connected.

Abstract: Provided are an anti-GITR monoclonal antibody and a humanized antibody thereof, which can be used to prepare a drug used for activating immune response, particularly a related drug for treating cancer.

Abstract: A mine explosion-isolating hoisting device with a built-in type permanent magnet motor includes a spindle fixed on the ground; a permanent magnet motor stator fixed on the spindle; a drum rotating relative to the spindle, the drum surrounding the spindle circumferentially; and a permanent magnet motor external rotor fixed by a spoke plate and rotating relative to the spindle; the drum is connected to the permanent magnet motor external rotor via an isolating disc; and a radial distance between an outer circumferential surface of the permanent magnet motor external rotor and an inner wall of the drum is greater than a preset value.

Abstract: A mine explosion-isolating hoisting device with a built-in type permanent magnet motor includes a spindle fixed on the ground; a permanent magnet motor stator fixed on the spindle; a drum rotating relative to the spindle, the drum surrounding the spindle circumferentially; and a permanent magnet motor external rotor fixed by a spoke plate and rotating relative to the spindle; the drum is connected to the permanent magnet motor external rotor via an isolating disc; and a radial distance between an outer circumferential surface of the permanent magnet motor external rotor and an inner wall of the drum is greater than a preset value.

Abstract: The present invention discloses a multi-channel impact-resistant intelligent-constant-deceleration hydraulic braking system, and relates to the field of safety braking control for mine hoist systems. A technical point of the braking system is that the braking system includes a braking circuit formed by a constant-deceleration hydraulic system, a constant-deceleration electrical closed-loop control system, and a detection and feedback apparatus. The constant-deceleration hydraulic system is provided with N+1 independent complete oil return channels, where N is a positive integer greater than or equal to 3. The oil return channels are disposed in parallel to form parallel independent braking circuits, that is, are “multi-channel” and do not have a “common output point”. The oil return channel includes a backup oil source, an electro-hydraulic signal conversion and amplification component, an operating mode switching apparatus, and an execution component that are sequentially connected.

Abstract: The present invention relates to a leakage proof member for buildings, particularly to a compressive stress water stopper, which functions as or substitutes a water stop strip in a concrete deformation joint. The compressive stress water stopper may be pre-installed before casting concrete or installed after concrete is cast. The compressive stress water stopper has an upper plate, a fork-shaped rubber plate, a tapered rubber plate and a lower plate whose screw holes are alternately inserted by a plurality of fastening bolts A and B which are fastened by fastening nuts, respectively. The stress and the adhering property of the bicomponent polysulfide rubber securely attach the fork-shaped sheets of the fork-shaped rubber plate to the concrete surfaces at the two sides of the deformation joint and seal the screw holes and the clearances in the concrete.

Abstract: The present invention relates to a leakage proof member for buildings, particularly to a compressive stress water stopper, which functions as or substitutes a water stop strip in a concrete deformation joint. The compressive stress water stopper may be pre-installed before casting concrete or installed after concrete is cast. The compressive stress water stopper has an upper plate, a fork-shaped rubber plate, a tapered rubber plate and a lower plate whose screw holes are alternately inserted by a plurality of fastening bolts A and B which are fastened by fastening nuts, respectively. The stress and the adhering property of the bicomponent polysulfide rubber securely attach the fork-shaped sheets of the fork-shaped rubber plate to the concrete surfaces at the two sides of the deformation joint and seal the screw holes and the clearances in the concrete.

Abstract: An electrical connector assembly (100) in accordance with the present invention, comprises a receptacle connector (20) and plug connector (10). The receptacle connector comprises an insulative housing (21) and a plurality of first terminals (24) received in the housing. The housing comprises a base portion (211) and a mating portion (212) extending from the base portion (211). The mating portion (212) comprises a top wall, a bottom wall and a pair of side walls connecting with the top and the bottom walls and defines a tongue (26) therein. A lateral side of tongue connects with one of the side walls, and another side of the tongue is spaced with the other side wall where a recess (262) is formed. The plug connector comprises an insulative housing (11) and a plurality of second terminals (14) received in the insulative housing. The housing comprises a base portion (111) and a pair of parallel tongues (113) extending from the base portion. A rib (114) is formed to connects the two tongues.

Abstract: An electrical connector (1) includes an insulative housing (10), a number of terminals (20) and a shielding shell. The housing includes a body portion, (11), a mating portion (12) extending forwardly from the body portion and a number of passageways (124) defined therein. The terminals includes a number of digital signal, power, grounding and analog signal terminals (221, 222, 223). The terminals have four groups (21, 22, 23, 24) arrayed in rows. The group (22) of terminals includes three analog signal terminals. The distance between the adjacent two analog signal terminals is twice the distance between adjacent two other types of terminals except the analog signal terminals, thereby reducing variation range of characteristic impedance of the connector.

Abstract: An electrical connector assembly (100) in accordance with the present invention, comprises a receptacle connector (20) and plug connector (10). The receptacle connector comprises an insulative housing (21) and a plurality of first terminals (24) received in the housing. The housing comprises a base portion (211) and a mating portion (212) extending from the base portion (211). The mating portion (212) comprises a top wall, a bottom wall and a pair of side walls connecting with the top and the bottom walls and defines a tongue (26) therein. A lateral side of tongue connects with one of the side walls, and another side of the tongue is spaced with the other side wall where a recess (262) is formed. The plug connector comprises an insulative housing (11) and a plurality of second terminals (14) received in the insulative housing. The housing comprises a base portion (111) and a pair of parallel tongues (113) extending from the base portion. A rib (114) is formed to connects the two tongues.