Patents by Inventor Zhenxun Wang

Zhenxun Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating a methionine-dependent cancer
    Patent number: 11872230
    Abstract: The present invention relates generally to a therapeutic protocol for treating a subject having cancer. Taught herein is a method of treating cancer or reducing the risk of recurrence of cancer in a subject following an anti-cancer therapy.
    Type: Grant
    Filed: May 16, 2022
    Date of Patent: January 16, 2024
    Assignee: Agency for Science, Technology and Research
    Inventors: Zhenxun Wang, Wai Leong Tam, Lian Yee Yip, Ying Swan Ho, Zhengwei Wu, Bing Lim
  • ANTISENSE COMPOUNDS AND USES THEREOF
    Publication number: 20220372473
    Abstract: The present invention provides compounds comprising oligonucleotides complementary to a pyruvate kinase M transcript. Certain such compounds are useful for hybridizing to a pyruvate kinase M transcript, including but not limited to a pyruvate kinase M transcript in a cell. In certain embodiments, such hybridization results in modulation of splicing of the pyruvate kinase M transcript. In certain embodiments, such compounds are used to treat one or more symptoms associated with cancer.
    Type: Application
    Filed: December 16, 2021
    Publication date: November 24, 2022
    Inventors: Frank Rigo, C. Frank Bennett, Adrian R. Krainer, Zhenxun Wang
  • METHOD OF TREATING A METHIONINE-DEPENDENT CANCER
    Publication number: 20220280520
    Abstract: The present invention relates generally to a therapeutic protocol for treating a subject having cancer. Taught herein is a method of treating cancer or reducing the risk of recurrence of cancer in a subject following an anti-cancer therapy.
    Type: Application
    Filed: May 16, 2022
    Publication date: September 8, 2022
    Inventors: Zhenxun Wang, Wai Leong Tam, Lian Yee Yip, Ying Swan Ho, Zhengwei Wu, Bing Lim
  • Method of treating a methionine-dependent cancer
    Patent number: 11376256
    Abstract: The present specification relates generally to a therapeutic protocol for treating a subject having cancer. Taught herein is a method of treating cancer or reducing the risk of recurrence of cancer in a subject following an anti-cancer therapy.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: July 5, 2022
    Assignee: Agency for Science, Technology and Research
    Inventors: Zhenxun Wang, Wai Leong Tam, Lian Yee Yip, Ying Swan Ho, Zhengwei Wu, Bing Lim
  • Antisense compounds and uses thereof
    Patent number: 11236330
    Abstract: The present invention provides compounds comprising oligonucleotides complementary to a pyruvate kinase M transcript. Certain such compounds are useful for hybridizing to a pyruvate kinase M transcript, including but not limited to a pyruvate kinase M transcript in a cell. In certain embodiments, such hybridization results in modulation of splicing of the pyruvate kinase M transcript. In certain embodiments, such compounds are used to treat one or more symptoms associated with cancer.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: February 1, 2022
    Assignees: Ionis Pharmaceuticals, Inc., Cold Spring Harbor Laboratory
    Inventors: Frank Rigo, C. Frank Bennett, Adrian R. Krainer, Zhenxun Wang
  • METHOD OF TREATING A METHIONINE-DEPENDENT CANCER
    Publication number: 20200022984
    Abstract: The present specification relates generally to a therapeutic protocol for treating a subject having cancer. Taught herein is a method of treating cancer or reducing the risk of recurrence of cancer in a subject following an anti-cancer therapy.
    Type: Application
    Filed: July 19, 2018
    Publication date: January 23, 2020
    Inventors: Zhenxun Wang, Wai Leong Tam, Lian Yee Yip, Ying Swan Ho, Zhengwei Wu, Bing Lim
  • ANTISENSE COMPOUNDS AND USES THEREOF
    Publication number: 20190249175
    Abstract: The present invention provides compounds comprising oligonucleotides complementary to a pyruvate kinase M transcript. Certain such compounds are useful for hybridizing to a pyruvate kinase M transcript, including but not limited to a pyruvate kinase M transcript in a cell. In certain embodiments, such hybridization results in modulation of splicing of the pyruvate kinase M transcript. In certain embodiments, such compounds are used to treat one or more symptoms associated with cancer.
    Type: Application
    Filed: October 2, 2018
    Publication date: August 15, 2019
    Applicants: Ionis Pharmaceuticals, Inc., Cold Spring Harbor Laboratory
    Inventors: Frank Rigo, C. Frank Bennett, Adrian R. Krainer, Zhenxun Wang
  • ANTISENSE COMPOUNDS AND USES THEREOF
    Publication number: 20150275211
    Abstract: The present invention provides compounds comprising oligonucleotides complementary to a pyruvate kinase M transcript. Certain such compounds are useful for hybridizing to a pyruvate kinase M transcript, including but not limited to a pyruvate kinase M transcript in a cell. In certain embodiments, such hybridization results in modulation of splicing of the pyruvate kinase M transcript. In certain embodiments, such compounds are used to treat one or more symptoms associated with cancer.
    Type: Application
    Filed: October 31, 2013
    Publication date: October 1, 2015
    Applicants: Cold Spring Harbor Laboratory, Isis Pharmaceuticals, Inc.
    Inventors: Frank Rigo, C. Bennett, Adrian R. Krainer, Zhenxun Wang