Abstract: The present disclosure relates to the technical field of data processing, and in particular to a method and a system for assessing drug use in children, and a computing device. The method includes: building a rational drug use (RDU) assessment model for clinical drug use in children; acquiring clinical drug use data of children and extracting classification information therefrom; according to the classification information, importing the clinical drug use data of children correspondingly into the RDU assessment model for data comparison to obtain comparison results; and summarizing all comparison results according to the classification information to generate rationality assessment results for clinical drug use in children. The present disclosure can effectively improve the efficiency of rationality assessment for clinical drug use in children, so as to realize the monitoring of clinical drug use in children.