Abstract: The present invention belongs to the technical field of medicines, and relates to a class of fused ring compound, and the preparation and use thereof. Test results show that the compounds can significantly inhibit the ATM kinase activity, have a good selectivity for the ATM target, and have the pharmaceutical use of treating cancer.

Abstract: Disclosed is a metal peroxide composite injectable hydrogel, a preparation method and use thereof. The preparation method comprises the step of dissolving a modified high-molecular polymer, a metal peroxide and a peroxidase in a solvent, mixing evenly, and standing to prepare the hydrogel, wherein the modified high-molecular polymer is a high-molecular polymer grafted with a phenolic hydroxyl group. According to the invention, the metal peroxide induces the modified high-molecular polymer to be quickly crosslinked under an action of the peroxidase to prepare the hydrogel, and the prepared hydrogel has good photo-thermal performance, antibacterial property, tissue adhesion, osteogenesis promoting effect, shape adaptability and injectability, can be well adapted to an irregular bone defect area, and is used for repairing a postoperative defect of tumor through a synergistic effect of multiple functions, which can effectively prevent tumor recurrence and reduce a possibility of implant material infection.

Abstract: There are provided systems and methods relating to checking and confirming merchandise purchased at shopping facilities. In one form, the system includes: a shopping cart containing merchandise items to be purchased; a sales transaction database; a point-of-sales system that creates transaction records identified by transaction identifiers; and a mobile device used by an employee that includes a sensor to scan a paper or digital receipt to obtain the transaction identifier and a camera to capture images of the items in the shopping cart. The system also includes a control circuit that receives the transaction identifier, accesses the database using the identifier to determine the purchased items; analyzes the images of the merchandise items in the shopping cart and creates a computer vision receipt listing detected items; compares the purchased items with the detected items; and takes an action if there is a discrepancy.

Abstract: Various embodiments disclose a 3D memory device, including a substrate; a plurality of conductor layers disposed on the substrate; a plurality of NAND strings disposed on the substrate; and a plurality of slit structures disposed on the substrate. The plurality of NAND strings can be arranged perpendicular to the substrate and in a hexagonal lattice orientation including a plurality of hexagons, and each hexagon including three pairs of sides with a first pair perpendicular to a first direction and parallel to a second direction. The second direction is perpendicular to the first direction. The plurality of slit structures can extend in the first direction.

Abstract: Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) In a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer.

Abstract: A processor includes compute units each including a first-level cache and each communicatively coupled to a co-compute unit (CCU) within a lower-level cache. In response to a compute unit receiving instructions to perform operations for an application, the compute unit determines one or more parameters based on the received instructions. The compute unit then sends the parameters and instructions to perform one or more operations on behalf of the compute unit to a respective CCU. The CCU then performs the operations based on the parameters and using the lower-level cache. Once the CCU has performed the operations, the CCU then sends the results of the operations back to the compute unit.

Abstract: A fire monitoring system and a container-type data center system. The fire monitoring system includes a filtering apparatus, a detection apparatus, and a control apparatus. The filtering apparatus includes a first stage filter and a second stage filter.

Abstract: Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.

Abstract: A transparent display panel includes: a substrate (100), and multiple repeating units (10) arranged in an array on the substrate. The non-transmissive region (A1) of the repeating unit includes: at least one pixel unit (P), N sets of first traces (11) extending in a first direction (X) and M sets of second traces (12) extending in a second direction (Y) electrically connected to the pixel unit. A set of first traces includes: multiple first signal lines (111) and at least one second signal line (112), an orthographic projection of at least one second signal line on substrate covers that of at least two first signal lines on substrate; or, a set of second traces includes: multiple third signal lines (121) and at least one fourth signal line (122), orthographic projection of at least one fourth signal line on substrate covers that of at least two third signal lines on substrate.

Abstract: The present disclosure provides an array substrate, a backlight and a display device which both include the array substrate. The array substrate includes multiple light-emitting units arranged in M rows and N columns and multiple first signal lines. Multiple first signal lines are divided into N groups, and each group of first signal lines is electrically connected to a column of light-emitting units. Each group of first signal lines includes at least two first signal lines, for each column of light-emitting units, at least two consecutive rows of light-emitting units are electrically connected to one of the at least two first signal lines, and the remaining at least one row of light-emitting unit is electrically connected to the other one of the at least two first signal lines, M is a positive integer greater than or equal to 3, N is a positive integer greater than or equal to 1.

Abstract: An array substrate includes M pixel lines and N pixel circuit groups. The M pixel lines are disposed in a display area and arranged in a first direction. The N pixel circuit groups are arranged in the first direction. M is an integer greater than or equal to 2, and N is a positive integer less than M. A pixel circuit group of the N pixel circuit groups is electrically connected to adjacent two pixel lines of the M pixel lines, and the first direction is one of a row direction and a column direction.

Abstract: A terminal positioning method, a terminal positioning device, a receiving end device and a core network device are provided, so as to solve the problem in the related art where the positioning accuracy of the terminal positioning method is low and it is impossible to meet the requirement on the positioning accuracy.

Abstract: Embodiments of the present disclosure provide an array substrate and method for manufacturing same, a display panel, and a display device, and relate to the field of display technologies. The array substrate includes a color filter layer, such that a distance between a light source on a side, distal from the color filter layer, of the base substrate and the color filter layer is less. Thus, light from regions of the color resist blocks is avoided being emitted from adjacent color resist blocks, and a cross color of the display panel is further avoided, such that the display effect of the display panel is great. In addition, the color resist block is at least partially overlapped with a second portion of a metal oxide pattern in an oxide thin film transistor, such that an overall footprint of the oxide thin film transistor and the color filter layer can be reduced, so as to acquire the display panel of high PPI.

Abstract: Disclosed are a display substrate and a display apparatus, the display substrate includes a display region and a non-display region, the display region is provided with a pixel circuit and a light emitting unit; each pixel circuit is connected with K light emitting devices emitting light of a same color; each pixel circuit includes a current control sub-circuit and a light emitting selection sub-circuit; the current control sub-circuit is configured to provide a drive current to a first node under control of a reset signal terminal, an initial signal terminal, a scan signal terminal, a data signal terminal, a light emitting control terminal, and a first power supply terminal; the light emitting selection sub-circuit is configured to sequentially provide a signal of the first node to the K light emitting devices emitting light of the same color under control of K light emitting selection signal terminals.

Abstract: A displaying base plate and a manufacturing method thereof, and a displaying device. The displaying base plate includes an active area and a non-active area located at the periphery of the active area, wherein the active area includes an opening area and a non-opening area. The displaying base plate includes a substrate and a thin-film transistor disposed on one side of the substrate, wherein the thin-film transistor includes a grid electrode, an active layer, a source-drain electrode and an auxiliary film layer, an excavation area is disposed on the auxiliary film layer, and an orthographic projection of the excavation area on the substrate at least partially covers the opening area.

Abstract: An array substrate, a detection method for the array substrate, and a tiled display panel. In the array substrate, each of pixels (1) comprises sub-pixels (01) of at least three colors and a pixel driving chip (02) for driving each sub-pixel (01) to emit light; each sub-pixel (01) comprises at least one inorganic light-emitting diode; a display area (A1) further comprises: a positive signal line (Hm) connected to a positive electrode of each inorganic light-emitting diode, and a data signal line (Dm), a scanning line (Sn), and a reference signal line (Vm) connected to each pixel driving chip (02); each pixel driving chip (02) is used for writing signals of the data signal line (Dm) into the sub-pixels (01) of different colors under the control of the corresponding scanning line (Sn) in a time division manner.

Abstract: Embodiments of the present disclosure provide a positioning method and apparatus, and a readable storage medium, relating to the technical field of communications. The method includes: obtaining a first timing error group configuration parameter; receiving the first reference signal to obtain first positioning measurement value, and determining first receiving timing errors of the first positioning measurement value; dividing the first receive timing errors into groups according to the first timing error group configuration parameter to obtain at least one first receive timing error group for positioning a UE. The first reference signal includes one of a positioning reference signal and a sounding reference signal; and the first positioning measurement value is used to represent a distance between a transmitting end and the receiving end of the first reference signal.

Abstract: A display device, a gate drive circuit, a shift register and a control method are disclosed. The shift register includes a first shift register unit and a second shift register unit, the first shift register unit is configured to write a first control signal to the first node, and write a first clock signal to the first signal output terminal under control of a voltage of the first node; the second shift register unit is configured to write a second clock signal to the second signal output terminal under control of the voltage of the first node; during time of a frame, the first clock signal and a first input signal provided by a first signal input terminal are pulse signals, and the second clock signal is a DC signal.

Abstract: An alignment mark includes a first alignment marker located on a first surface of a substrate and a second alignment marker located on a second surface of the substrate. The second alignment marker is arranged to be matched with the first alignment marker, and capable of representing a process variation between the second alignment marker and the first alignment marker.

Abstract: Disclosed are a thin film transistor and a manufacturing method therefor, a displaying base plate and a displaying apparatus. The thin film transistor includes an active layer, a first insulating layer and a gate layer which are disposed in stack, wherein the active layer includes a source contact area, a drain contact area, and a channel area connecting the source contact area and the drain contact area; the channel area includes a first channel area, a first resistance area and a second channel area sequentially disposed in a first direction; the gate layer includes a first gate and a second gate which are separately disposed; an orthographic projection of the first gate on a plane where the active layer is located covers the first channel area; and an orthographic projection of the second gate on a plane where the active layer is located covers the second channel area.