Abstract: The present disclosure relates to the field of regulation of plant performance genes, in particular to a pectin methylesterase inhibitor gene GhPMEI39 and application of its encoded protein. The gene sequence of the pectin methylesterase inhibitor gene GhPMEI39 is shown in SEQ ID NO: 1. According to the present disclosure, a public database is used to screen target genes, primers are designed to clone the target genes, its cotton transgenic materials and Arabidopsis thaliana transgenic materials are constructed, and plant development phenotypes after overexpression and constitutive expression of pectin methylesterase inhibitor protein are analyzed, and the role of the pectin methylesterase inhibitor gene GhPMEI39 in related functions such as plant flowering and inflorescence morphology is verified.

Abstract: The present invention features interferon-free therapies for the treatment of HCV. Preferably, the treatment is over a shorter duration of treatment, such as no more than 12 weeks. In one aspect, the treatment comprises administering at least two direct acting antiviral agents to a subject with HCV infection, wherein the treatment lasts for 12 weeks and does not include administration of either interferon or ribavirin, and said at least two direct acting antiviral agents comprise (a) Compound 1 or a pharmaceutically acceptable salt thereof and (b) Compound 2 or a pharmaceutically acceptable salt thereof.

Abstract: An unidirectional nanopore dehydration-based functional polymer membrane or hydrogel membrane, preparation method thereof and device thereof. Adding an aqueous polymer solution or a polymer mixture solution into a mold through a sampling hole on the top of a container with a nanoporous filter film as the bottom, after closing said sampling hole, the water molecules in the solution are dehydrated in one direction downward through the nanopores of the filter film, and obtain said polymer membrane or hydrogel membrane on the upper surface of the nanoporous filter film; it can also undergo in situ polymerization with pyrrole in an aqueous solution to obtain a conductive PM or PHM modified by polypyrrole. The invention adopts a UND-based mold, and green processing obtains a novel polymer material with an ordered molecular arrangement, which has the characteristics of flexibility, transparency, and robust mechanical properties. The polymeric material has broad applications.