Patents by Inventor Zhexun SUN

Zhexun SUN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LUBRICATING BLOCK COPOLYMERS AND THEIR USE AS BIOMIMETIC BOUNDARY LUBRICANTS
    Publication number: 20230210892
    Abstract: The invention relates to methods of lubricating biological tissue, such as joints, bone, ocular tissue, nasal tissue, tendons, tendon capsule, and vaginal tissue, by contacting the biological tissue with an effective amount of a block copolymer lubricating composition which functions at least or better than lubricin. In particular embodiments, the method is used to treat osteoarthritis. In specific embodiments, the block copolymer has an ammonium-containing polymer block and a non-ionic hydrophilic polymer block, or the copolymer has a carboxylic acid-containing polymer block and a non-acid non-ionic hydrophilic polymer block.
    Type: Application
    Filed: July 1, 2022
    Publication date: July 6, 2023
    Applicant: CORNELL UNIVERSITY
    Inventors: David PUTNAM, Lawrence BONASSAR, Zhexun SUN
  • BIOCOMPATIBLE MATERIAL AND METHODS FOR MAKING AND USING THE SAME
    Publication number: 20230173074
    Abstract: The present disclosure provides a composition comprising a first polymer with a high intrinsic viscosity [?] of at least 500 ml/g and a second polymer with a low intrinsic viscosity [?] lower than the first polymer and less than 1800 ml/g. More specifically, the present disclosure provides a hydrogel formed with the composition and a pharmaceutical, as well as a method for generating a hydrogel.
    Type: Application
    Filed: April 22, 2021
    Publication date: June 8, 2023
    Inventors: Yu YU, Guanqun ZHOU, Zhexun SUN
  • COMPOSITIONS AND METHODS FOR CONTROLLED RELEASE OF TARGET AGENT
    Publication number: 20230093832
    Abstract: Provided are compositions and methods for controlled release of macromolecules (such as proteins and polypeptides). The composition comprises at least a first hydrogel forming polymer and at least a second hydrogel forming polymer. Also provided are methods for preparing and using the composition.
    Type: Application
    Filed: January 13, 2021
    Publication date: March 30, 2023
    Applicant: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Ying CHAU, Chi Ming Laurence LAU, Yu YU, Zhexun SUN
  • Lubricating block copolymers and their use as biomimetic boundary lubricants
    Patent number: 11376276
    Abstract: The invention relates to methods of lubricating biological tissue, such as joints, bone, ocular tissue, nasal tissue, tendons, tendon capsule, and vaginal tissue, by contacting the biological tissue with an effective amount of a block copolymer lubricating composition which functions at least or better than lubricin. In particular embodiments, the method is used to treat osteoarthritis. In specific embodiments, the block copolymer has an ammonium-containing polymer block and a non-ionic hydrophilic polymer block, or the copolymer has a carboxylic acid-containing polymer block and a non-acid non-ionic hydrophilic polymer block.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: July 5, 2022
    Assignee: CORNELL UNIVERSITY
    Inventors: David Putnam, Lawrence Bonassar, Zhexun Sun
  • LUBRICATING BLOCK COPOLYMERS AND THEIR USE AS BIOMIMETIC BOUNDARY LUBRICANTS
    Publication number: 20190231811
    Abstract: The invention relates to methods of lubricating biological tissue, such as joints, bone, ocular tissue, nasal tissue, tendons, tendon capsule, and vaginal tissue, by contacting the biological tissue with an effective amount of a block copolymer lubricating composition which functions at least or better than lubricin. In particular embodiments, the method is used to treat osteoarthritis. In specific embodiments, the block copolymer has an ammonium-containing polymer block and a non-ionic hydrophilic polymer block, or the copolymer has a carboxylic acid-containing polymer block and a non-acid non-ionic hydrophilic polymer block.
    Type: Application
    Filed: October 4, 2017
    Publication date: August 1, 2019
    Inventors: David PUTNAM, Lawrence BONASSAR, Zhexun SUN