Abstract: The present invention provides a mounting device and method of a tandem-type rock mass three-dimensional disturbance stress sensor, and the device is formed by sequentially connecting a head end unit, a plurality of repetitive units, and a tail end unit. This invention enables the accurate installation of multiple three-dimensional disturbance stress sensors within a single borehole without requiring full-hole grouting. As a result, the sensors can be mounted in a multi-point distributed arrangement within the same borehole. Adhesive fluid in a top adhesive cartridge is triggered through a head end triggering mechanism to bond a three-dimensional disturbance stress sensor in a first repetitive unit, and adhesive fluid in a corresponding first adhesive cartridge is triggered by using the first triggering mechanism to bond a three-dimensional disturbance stress sensor in a next repetitive unit, to ensure good coupling between the three-dimensional disturbance stress sensor and a rock mass.

Abstract: The present disclosure relates to a GLP-1R agonist compound and use thereof, and specifically provides a compound represented by Formula I, or an isotope-labelled compound, a stereoisomer, or a pharmaceutically acceptable salt thereof, and use thereof as a medicament. The compound exhibits excellent agonistic effects and pharmacodynamic properties on GLP-1R and, as a modulator, is useful for manufacturing a medicament for the treatment, amelioration, or prevention of metabolic diseases and related diseases, thus having broad application prospects.

Abstract: A method for controlling the quality of traditional Chinese patent medicines is based on metagenomics. The method includes extracting genomic DNA of a sample of the traditional Chinese patent medicine, constructing a library of the genomic DNA based on a high-throughput sequencing platform, and performing metagenomic sequencing. The data obtained from the metagenomic sequencing is processed to obtain the ITS2 sequence of the traditional Chinese patent medicine sample A BLAST alignment is performed on the ITS2 sequence in the DNA Barcoding System for Identifying Herbal Medicine, to obtain species identification results. The obtained identification results are compared with the labeled species of the traditional Chinese patent medicine to obtain a conclusion about the quality of the traditional Chinese patent medicine sample.

Abstract: Provided is a plasmid library comprising a DNA insertion site and two barcode sequences located upstream and downstream of the site. The combinations of two barcode sequences of any two plasmids selected from the library are different. Also provided is a method for high-throughput paired-end sequencing of an inserted DNA using the plasmid library.

Abstract: A method for controlling the quality of traditional Chinese patent medicines is based on metagenomics. The method includes extracting genomic DNA of a sample of the traditional Chinese patent medicine, constructing a library of the genomic DNA based on a high-throughput sequencing platform, and performing metagenomic sequencing. The data obtained from the metagenomic sequencing is processed to obtain the ITS2 sequence of the traditional Chinese patent medicine sample A BLAST alignment is performed on the ITS2 sequence in the DNA Barcoding System for Identifying Herbal Medicine, to obtain species identification results. The obtained identification results are compared with the labeled species of the traditional Chinese patent medicine to obtain a conclusion about the quality of the traditional Chinese patent medicine sample.

Abstract: The equipment of high-gravity multi-rotors zigzag rotating beds according to the present invention comprises a casing, a gas inlet and a liquid outlet being provided at the bottom of the casing, a gas outlet and a liquid inlet being provided at the top of the casing, a rotating shaft being provided at the center of the casing and going through the top and the bottom of the casing, a plurality of rotors being installed in series on the rotating shaft and being arranged in layers from top to bottom, and a middle feed inlet being provided on the side of the casing and being communicated with zigzag channels. The rotor comprises a mobile disk fixed on the rotating shaft and an immobile disk fixed on the casing, A series of concentric mobile and immobile circular baffle-sheets are fitted on the mobile disk and the immobile disk respectively.

Abstract: The equipment of high-gravity multi-rotors zigzag rotating beds according to the present invention comprises a casing, a gas inlet and a liquid outlet being provided at the bottom of the casing, a gas outlet and a liquid inlet being provided at the top of the casing, a rotating shaft being provided at the center of the casing and going through the top and the bottom of the casing, a plurality of rotors being installed in series on the rotating shaft and being arranged in layers from top to bottom, and a middle feed inlet being provided on the side of the casing and being communicated with zigzag channels. The rotor comprises a mobile disk fixed on the rotating shaft and an immobile disk fixed on the casing, A series of concentric mobile and immobile circular baffle-sheets are fitted on the mobile disk and the immobile disk respectively.