Abstract: The embodiments of the present disclosure provide a method for radiation therapy guidance. The method may include obtain first surface data of a target object to be treated by using an optical camera, wherein the first surface data may reflect the body surface condition of the target object before a treatment fraction; obtain a historical anatomical image of the target object; and determine whether an anatomical image of the target object needs to be reshot for the treatment fraction based on the historical anatomical image and the first surface data.

Abstract: The present disclosure is related to systems and methods for radiation. The method may include obtaining a plurality of reference images of a target of a subject and reference physiological motion information of the subject. The plurality of reference images and the reference physiological motion information may be acquired in a radiation period. The method may include establishing a correlation model based on the plurality of reference images and the reference physiological motion information. The method may include monitoring real-time motion information of the target based on the correlation model during a radiation operation performed during the radiation period.