Patents by Inventor Zhi M. Wang

Zhi M. Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of producing effective recombinant serine protease inhibitors and uses of these inhibitors
    Patent number: 5612194
    Abstract: A method of producing a recombinant serine protease inhibitor capable of effectively modulating serine protease activity is provided. Compositions capable of modulating serine protease activity and use of such compositions to regulate inflammatory processes in cells are also provided.
    Type: Grant
    Filed: July 19, 1994
    Date of Patent: March 18, 1997
    Assignee: Trustees of the University of Pennsylvania
    Inventors: Harvey Rubin, Barry Cooperman, Norman Schechter, Michael Plotnick, Zhi M. Wang
  • .alpha.-1-antichymotrypsin, analogues and methods of production
    Patent number: 5367064
    Abstract: The invention provides .alpha.-1-antichymotrypsin and protein preparations comprising human .alpha.-1-antichymotrypsin produced by E. coli cells transformed with a DNA sequence encoding human .alpha.-1-antichymotrypsin. The invention also provides methods for producing .alpha.-1-antichymotrypsin. The invention further provides analogues of .alpha.-1-antichymotrypsin that exhibit antichymotrypsin, anti-trypsin and anti-thrombin activity and methods of producing the analogues.
    Type: Grant
    Filed: January 15, 1993
    Date of Patent: November 22, 1994
    Assignee: The Trustees of the University of Pennylsvania
    Inventors: Harvey Rubin, Zhi M. Wang, Barry S. Cooperman, Norman Schechter
  • .alpha.-1-antichymotrypsin, analogues and methods of production
    Patent number: 5266465
    Abstract: The invention provides .alpha.-1-antichymotrypsin and protein preparations comprising human .alpha.-1-antichymotrypsin produced by E. coli cells transformed with a DNA sequence encoding human .alpha.-1-antichymotrypsin. The invention also provides methods for producing .alpha.-1-antichymotrypsin. The invention further provides analogues of .alpha.-1-antichymotrypsin that exhibit antichymotrypsin, anti-trypsin and anti-thrombin activity and methods of producing the analogues.
    Type: Grant
    Filed: July 24, 1991
    Date of Patent: November 30, 1993
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Harvey Rubin, Zhi M. Wang, Barry S. Cooperman, Norman Schecter
  • .alpha.-1-antichymotrypsin, analogues and methods of production
    Patent number: 5252725
    Abstract: The invention provides .alpha.-1-antichymotrypsin and protein preparations comprising human .alpha.-1-antichymotrypsin produced by E. coli cells transformed with a DNA sequence encoding human .alpha.-1-antichymotrypsin. The invention also provides methods for producing .alpha.-1-antichymotrypsin. The invention further provides analogues of .alpha.-1-antichymotrypsin that exhibit antichymotrypsin, anti-trypsin and anti-thrombin activity and methods of producing the analogues.
    Type: Grant
    Filed: July 24, 1991
    Date of Patent: October 12, 1993
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Harvey Rubin, Zhi M. Wang
  • .alpha.-1-antichymotrypsin, analogues and methods of production
    Patent number: 5079336
    Abstract: The invention provides .alpha.-1-antichymotrypsin and protein preparations comprising human .alpha.-1-antichymotrypsin produced by E. coli cells transformed with a DNA sequence encoding human .alpha.-1-antichymotrypsin. The invention also provides methods for producing .alpha.-1-antichymotrypsin. The invention further provides analogues of .alpha.-1-antichymotrypsin that exhibit antichymotrypsin, anti-trypsin and anti-thrombin activity and methods of producing the analogues.
    Type: Grant
    Filed: June 23, 1989
    Date of Patent: January 7, 1992
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Harvey Rubin, Zhi M. Wang