Abstract: Provided are an isolated binding protein including an antigen binding domain of cardiac troponin I (cTnI), as well as a preparation and uses of the binding protein. The antigen binding domain includes at least one complementary determining region selected from the amino acid sequences defined herein; or the antigen-binding domain has at least 80% sequence identity with the complementary determining regions of said amino acid sequences and has an affinity for cardiac troponin I of KD?3.33×10?8 mo/L. The binding protein may be used in the field of cTnI protein detection.

Abstract: Provided is an isolated binding protein including an antigen-binding domain that binds to NS1 protein. The isolated binding protein includes specific heavy chain CDRs and light chain CDRs. The binding protein can specifically recognize and bind to NS1, and has relatively high sensitivity and specificity, thereby achieving the detection of dengue virus. Moreover, the binding protein is not required to be produced by inducing hybridoma cells in mouse abdominal cavity, and thus it is simple in production and has more stable antibody function.

Abstract: Provided is an isolated binding protein including an antigen binding domain binding to an NS1 protein, and including specific heavy chain CDR and light chain CDR. The binding protein can specifically identify and bind to NS1, and has relatively high sensitivity and specificity, so as to detect dengue vims. Moreover, the binding protein does not need to be produced by injecting hybridoma cells into mouse peritoneal cavity, while simplifying production, thus stabilizing antibody functionality.

Abstract: Disclosed is a magnetic pressure retaining control device, which comprises: a valve seat, a magnetic valve cover, and a trigger magnetic member for repelling the magnetic valve cover; the magnetic valve cover and an open end of the valve seat are movably connected; when the magnetic valve cover is in an open state, the trigger magnetic member is opposite to an end surface of the magnetic valve cover away from an inside of the valve seat. A cylindrical magnet is also arranged in the valve seat. By the magnetic between the trigger magnet and the magnetic valve cover, and the magnetic between the magnetic valve cover and the valve seat, a reliable guarantee for the closure between the magnetic valve cover and the valve seat is provided. The valve seat and the valve cover are tightly closed under different conditions.

Abstract: An internal blowout-prevention gas-retaining connector has a body mounted at the bottom of a drill pipe. The body includes a valve pipe section and a connecting pipe section arranged from top to bottom. The bottom of the valve pipe section is inserted into the top of the connecting pipe section. The blowout-prevention valve seat is provided at a bottom end of the valve pipe section while a blowout-prevention valve bonnet is provided on a bottom surface of the valve pipe section. The edge of the blowout-prevention valve bonnet is rotatably connected to a bottom surface edge of the valve pipe section. A torsion spring is provided on a bottom surface of the blowout-prevention valve bonnet. One end of the torsion spring is connected to the bottom surface of the blowout-prevention valve bonnet while the other end is connected to the inner wall of the connecting pipe section.

Abstract: A simulation device for magnetic closing of flap valve is disclosed, which includes a worktable, a driving mechanism for driving the worktable to rotate, a valve seat, a magnetic valve cover movably connected with the valve seat, a first magnet for repelling the magnetic valve cover, a cylinder, a lifting equipment for driving the cylinder to rise and fall. When the cylinder is inserted into the valve seat driven by the lifting equipment, the cylinder prevents the closure of the magnetic valve cover. When the cylinder is out of contact with the magnetic valve cover driven by the lifting equipment, the magnetic valve cover is closed, and the worktable in the simulation device can rotate and turn over, so that the closing process of flap valve (valve seat and valve cover) in any direction of deep drilling coring under the action of magnetic force is simulated.

Abstract: Disclosed is an isolated binding protein including a cardiac troponin I (cTnI) antigen binding domain, and preparation and a use and the like of the binding protein. The antigen binding domain includes at least one complementarity determining region selected from an amino acid sequence defined in this article, or has at least 80% sequence identity with the complementarity determining region of the amino acid sequence and has KD?9.96×10?8 mol/L affinity with cTnI. The binding protein may be used in the detection field of the cTnI protein.

Abstract: The present disclosure relates to the field of medical diagnosis, and specifically, relates to a synthetic peptide for detecting HIV-1. The synthetic peptide is obtained by mutating the amino acid sequence set forth as SEQ ID NO: 1. The synthetic peptide can better detect anti-HIV-1 antibodies, and can better avoid potential “false negative” and “false positive” results.

Abstract: A biomimetic tower climbing robot and a tower climbing method thereof are provided. The robot mainly includes a main control body module and clamping and moving mechanism modules; two ends of the main control body module are connected to one clamping and moving mechanism module through an elastic universal joint respectively, two clamping and moving mechanism modules can alternately lock and unlock an anti-fall track of an iron tower, and the main control body module alternately pushes the clamping and moving mechanism module at its upper end upwards and pulls the clamping and moving mechanism module at its lower end upwards to achieve climbing of the robot along the anti-fall track.

Abstract: A biomimetic tower climbing robot and a tower climbing method thereof are provided. The robot mainly includes a main control body module and clamping and moving mechanism modules; two ends of the main control body module are connected to one clamping and moving mechanism module through an elastic universal joint respectively, two clamping and moving mechanism modules can alternately lock and unlock an anti-fall track of an iron tower, and the main control body module alternately pushes the clamping and moving mechanism module at its upper end upwards and pulls the clamping and moving mechanism module at its lower end upwards to achieve climbing of the robot along the anti-fall track.

Abstract: Disclosed is a continuous conduit apparatus based on guiding and injecting integrated mechanism, which comprises a straightening apparatus and a pair of sprocket and chain clamping assemblies. The pair of sprocket and chain clamping assemblies are configured to clamp the conduit and pull the conduit to go downwards a well or upwards a lifting direction. Between the pair of sprocket and chain clamping assemblies, a conduit guide channel applied for the conduit to passing through is formed. An inlet and an outlet of the conduit guide channel are not situated in a straight line, and the straightening apparatus are configured to straighten the conduit. Each of the two sprocket and chain clamping assemblies comprises a sprocket set, a chain, a plurality of clamping blocks mounted on the chain, and a pushing plate configured to press the clamping blocks.

Abstract: Disclosed is a continuous conduit operation apparatus, which comprises a folding frame and a guiding and injecting integrated mechanism configured to pull the conduit to go downwards a well or upwards a lifting direction. The folding frame comprises a base, a mounting frame connected to the base in a movable connection, and a telescopic mechanism configured to rotate the mounting frame in a vertical plane around a position of the movable connection. One end of the telescopic mechanism is movably connected to the base, another end of the telescopic mechanism is movably connected to the mounting frame. The guiding and injecting integrated mechanism is arranged on the mounting frame. The present disclosure integrates the guiding function and the injection function to reduce the height of the apparatus and is suitable for operation environment with limited space and height.

Abstract: This application provides a die package structure including a package substrate, a die, and a first package body. The package substrate has a first surface and a second surface opposite each other. The die is coupled to the package substrate, and the die has a hotspot. A heat dissipation connection point is disposed on the first surface of the package substrate, and a heat conduction channel that communicates the heat dissipation connection point with the hotspot is formed in the package substrate. A first connection terminal for connecting to an external device is disposed on the second surface. The first package body is disposed on the first surface, a heat conduction structure is formed in the first package body, and the heat conduction structure extends from the heat dissipation connection point to a surface of the first package body.

Abstract: Provided is an isolated binding protein including an antigen binding domain binding to an NS1 protein, and comprising specific heavy chain CDR and light chain CDR. The binding protein can specifically identify and bind to NS1, and has relatively high sensitivity and specificity, so as to detect dengue virus. Moreover, the binding protein does not need to be produced by injecting hybridoma cells into mouse peritoneal cavity, while simplifying production, thus stabilizing antibody functionality.

Abstract: Disclosed in the present disclosure is a double-deck multi-span bridge construction method. According to the double-deck bridge construction method of the present disclosure, construction is carried out by using a method of disassembling a support jig frame in a graded and span-separated mode, an upper chord jig frame and a lower chord jig frame can be used in a recycle manner, and construction costs are reduced. In addition, a construction period of building the support jig frame is shortened, and other construction operations can be synchronously carried out on a span in which the jig frame is disassembled, for example, fire retardant coating construction can be carried out on a mounted bridge deck after the jig frame is disassembled, and the construction period of a double-deck multi-span bridge is effectively shortened.

Abstract: A driving system for a core drilling rig has a driving motor. The driving motor has an outer rotor and an inner stator, and mutually-matched convex ribs are provided on the inner wall of the outer rotor and the outer wall of the inner stator. The outer rotor and the inner stator are in clearance fit. A clearance between the outer rotor and the inner stator is a driving liquid channel. The length of the outer rotor is less than that of the inner stator. The outer rotor is provided between the front and rear ends of the inner stator. The outer rotor is connected to an outer cylinder. The rear end of the inner stator is connected to a coupling.

Abstract: A drilling fluid channel structure of a core drilling rig includes a fluid channel activation module, a pressure relief module, a flow diverging and blocking module, a driving fluid channel and a cooling fluid channel. The fluid channel activation module, the pressure relief module and the flow diverging and blocking module are connected sequentially from the rear to the front. The driving fluid channel and the cooling fluid channel are connected at the rear side thereof to the flow diverging and blocking module. The driving fluid channel includes a driving section located between a stator and a rotor of a driving motor. The driving fluid channel is provided with a driving fluid outlet at the front side of the driving section. The cooling fluid channel passes through a layer disposed between an integrity-preserving compartment and an outer barrel.

Abstract: A core sampling and preservation system comprises the following sequentially connected modules: a drive module (300), a preservation module (200) and a core sampling module (100). The core sampling module (100) comprises a core drilling tool and a core sample storage compartment. The preservation module (200) comprises a core sample preservation container. The drive module comprises a core drill having a liquid channel. The core sample preservation container comprises an inner core barrel (28), an outer core barrel (26) and an energy storage device (229). The outer core barrel (26) is sleeved onto the inner core barrel (28). An upper end of the inner core barrel (28) is in communication with a liquid nitrogen storage tank (225). The liquid nitrogen storage tank (225) is positioned inside the outer core barrel (26). The energy storage device (229) is in communication with the outer core barrel (26). The outer core barrel (26) is provided with a butterfly valve (23).

Abstract: Disclosed is a magnetic pressure retaining control device, which comprises: a valve seat, a magnetic valve cover, and a trigger magnetic member for repelling the magnetic valve cover; the magnetic valve cover and an open end of the valve seat are movably connected; when the magnetic valve cover is in an open state, the trigger magnetic member is opposite to an end surface of the magnetic valve cover away from an inside of the valve seat. A cylindrical magnet is also arranged in the valve seat. By the magnetic between the trigger magnet and the magnetic valve cover, and the magnetic between the magnetic valve cover and the valve seat, a reliable guarantee for the closure between the magnetic valve cover and the valve seat is provided. The valve seat and the valve cover are tightly closed under different conditions.

Abstract: A system for the in-situ retained coring of a rock sample has a driving module (300), a retaining module (200), and a coring module (100) which are connected in sequence. The coring module (100) includes a rock core drilling tool and a rock core sample storage cylinder, the retaining module (200) includes a rock core sample retaining compartment. The driving module includes a coring drill machine that has a drill machine outer cylinder unlocking mechanism. The rock core drilling tool includes a coring drill tool, a core catcher (11), and an inner core pipe (12). The coring drill tool has an outer core pipe (13) and a hollow drill bit (14). The rock core sample retaining compartment has an inner coring cylinder (28), an outer coring cylinder (26), and an energy accumulator (229).