Abstract: An apparatus for ventilatory treatment is provided. The apparatus may include at least one gas entrance configured to introduce a first gas into the apparatus and introduce a second gas into the apparatus; a gas mixing assembly configured to mix the first gas and the second gas to generate a mixed gas; a gas export configured to discharge a flow of the mixed gas; and a noise reduction assembly configured to reduce noise of the apparatus.

Abstract: A blower device and a respirator including the blower device. The blower device comprises a case, a blower vibration source disposed within the case and a buffering assembly for associating the blower vibration source and the case, wherein the vibration absorption assembly comprises at least two of a locating buffering member associated with a top portion of the blower vibration source, a connection buffering member in which at least a part of the blower vibration source is received and a support buffering member associated with a bottom portion of the blower vibration source. The blower device is capable of effectively buffering vibration of the blower device, decreasing noise transmission and has a simple structure.

Abstract: The present application belongs to the technical field of proteolysis-targeting chimeras (PROTACs), and discloses a PROTAC molecule and a preparation method and use thereof. A ligand for a target protein in the PROTAC molecule of the present application is a pyridine carboxylic acid-1-oxide derivative. In cell and zebrafish experiments, the PROTAC molecule exhibits no toxic and side effects at a drug concentration allowing a desired effect. At a cellular level, an inhibition level of the PROTAC molecule for human tyrosinase (TYR) reaches less than or equal to 1 ?mol/L. The PROTAC molecule in the present application can significantly reduce the generation of melanin by degrading TYR, and has excellent solubility, safety, and efficacy and a low effective concentration.

Abstract: The present application proposes a composite separator, including: a base membrane, a first nanofiber layer, and a ceramic powder. The first nanofiber layer is positioned on a first side of the base membrane. The ceramic powder forms a first ceramic coating positioned between the first nanofiber layer and the base membrane, or, the ceramic powder is added to the first nanofiber layer. In addition, the present application further proposes a method for preparing the composite separator, and a battery.

Abstract: A blower device and a respirator including the blower device. The blower device comprises a case, a blower vibration source disposed within the case and a buffering assembly for associating the blower vibration source and the case, wherein the vibration absorption assembly comprises at least two of a locating buffering member associated with a top portion of the blower vibration source, a connection buffering member in which at least a part of the blower vibration source is received and a support buffering member associated with a bottom portion of the blower vibration source. The blower device is capable of effectively buffering vibration of the blower device, decreasing noise transmission and has a simple structure.

Abstract: A tube assembly includes a first tube piece and a second tube piece. The first tube piece includes an inlet end connecting a gas source and an outlet end connecting the second tube piece. The first tube piece includes a discharging hole that is configured so that, in a connecting state, the discharging hole is closed to make the gas to enter the second tube piece, in the separating state, the discharging hole is opened to make the gas to be discharged outside from the discharging hole. The tube assembly includes a valve member that is configured so that, in the connecting state, the valve member opens the outlet end of the first tube piece to make the gas to enter the second tube piece, and in the separating state, the valve member closes the outlet end to make the gas to be discharged outside from the discharging hole.

Abstract: Provided is a method for determining a respiratory phase, applied to a ventilation therapy device including a respiratory conduit. The method includes: acquiring a gas flow value of the respiratory conduit, and acquiring a pressure value of a pressure sensor, wherein the pressure sensor is used for collecting a pressure in the respiratory conduit; converting the gas flow value and the pressure value into a first value and a second value under a same reference; and determining a current respiratory phase of a patient based on a difference of the first value and the second value.

Abstract: A virtual wearing method for a mask includes: acquiring a facial image of a user; determining actual facial feature data according to the facial image; determining and displaying one or more matched first masks of various models according to the actual facial feature data; determining a target mask from the first masks according to received first input from the user; and generating wearing picture information according to the facial image and the target mask, and displaying the wearing picture information. It can not only accurately match a plurality of first masks of different types and sizes suitable for the facial features of the user according to the facial feature data of the user, but also generate and display the wearing picture information through virtual reality and other technologies, so as to simulate the effect of the user wearing the target mask.

Abstract: A heating control circuit and a ventilator are provided. The heating control circuit includes a control device and a switching device, an input end of the control device being connected to an alternating-current power source, an output end thereof being connected to a control end of the switching device, and an output end of the switching device is connected to a heating member; and the control device is configured to generate, according to different output voltages of the alternating-current power source, a driving signal for controlling a duty ratio of the switch device to adaptively change, so that the power output from the switching device to the heating member is constant.

Abstract: A water tank mounting structure and a ventilation treatment apparatus for such structure. The water tank mounting structure comprises a cavity for containing a water tank and a side wall defining the cavity, wherein the side wall comprises an inner side wall spaced apart from an outer side, a first gas hole provided in the inner side wall, and a second gas hole provided in the outer side wall, both holes arranged in a staggered manner perpendicular to the side wall. The arrangement of the double-layer side wall, and the first and second gas holes in the inner and outer side walls, respectively, allows for hot gas in the cavity to be effectively removed. The staggered arrangement of the gas holes allows for water to flow downward along the side wall without invading the cavity when water enters through the second gas hole. A waterproof effect is achieved.

Abstract: An oxygen generator includes an adsorption tower and an exhaust muffler. The adsorption tower includes a loading cavity for loading a molecular sieve, and a nitrogen exhaust port in communication with the filling cavity; the exhaust muffler includes a gas inlet and a gas outlet, the gas inlet being in communication with the nitrogen exhaust port; and the exhaust muffler is configured to only allow a gas to flow unidirectionally from the gas inlet to the gas outlet. In the oxygen generator, the exhaust muffler is arranged at the nitrogen exhaust port of the adsorption tower, and the exhaust muffler is configured to only allow a gas to flow unidirectionally from the gas inlet to the gas outlet.

Abstract: An exhaust assembly, a ventilation assembly, a frame assembly and a mask system. When the mask system is worn, the nostrils and the mouth of a user are respectively covered by means of a nose structural body and a mouth structural body, which can meet the requirement of mouth breathing and thus has the advantage of good clinical blood gas parameters. Since the mask system seals around the nostrils of the user and thus avoids pressing the bridge of nose or two sides of the wing of nose of the user, the mask system has a smaller and lighter structure and better visibility, and thus has improved comfort. Compared with a full-face mask, the nasal mask is not prone to feeling claustrophobic and has better compatibility for people. The mask system can improve the treatment effect and treatment compliance.

Abstract: An exhaust assembly, a frame assembly, a cushion assembly and a patient interface device are provided. The patient interface device includes: a cushion assembly including a nasal cushion to be in contact with a face of a patient, the nasal cushion is configured to be adaptively fitted around nostrils of the patient in response to the patient interface device being worn by the patient, and the nasal cushion is configured to, when being pressed against the basis nasi of the patient due to a pressurized gas to seal, apply no clamping effect on the ala nasi of the patient; a frame assembly with two sides being connected to the nasal cushion and a vent pipe, respectively; and a head strap connected to the frame, the head strap is configured to be fixed around the head of the patient in response to the patient interface device being worn by the patient.

Abstract: An oronasal cushion includes a nasal structure and an oral structure that are connected to each other. A penetrating cavity is formed inside the nasal structure and the oral structure. The cavity can receive pressurized gas. The nasal structure fits around a wearer's nostrils to seal. The oral structure fits around the wearer's mouth to seal. The nasal structure is configured to not pinched against the wearer's nose when sealed against the wearer's nose base by means of pressurized gas. The oral structure is configured to accommodate and fit around the wearer's mouth in response to the oronasal cushion being put on by the wearer. The oral structure includes an oral soft pad in contact with the wearer's face and a reinforcing structure connected to the oral soft pad.

Abstract: A fire protection device includes a housing, a valve body, a torsion spring, and a meltable member, a fluid passage is provided in the housing, the fluid passage is provided with a first opening and a second opening, the first opening and the second opening are used for connecting with a pipeline of an oxygen therapy instrument or a patient end, respectively; the valve body is located in the fluid passage and is rotatably connected to the housing; the valve body is provided with an accommodating cavity, and the fluid passage and the accommodating cavity are two spaces independent from each other; the torsion spring is embedded in the accommodating cavity so as to drive the relative rotation of the valve body and the housing; and the meltable member is disposed on an inner wall of the fluid passage.

Abstract: Provided in the present invention is a multi-element co-doped sodium-ion positive electrode material, which is characterized in that the phase of the positive electrode material is an O3 phase, the space group thereof is R-3m, and the chemical formula thereof is Na?MaLibCucTidO2+?, wherein M is at least one of Ni, Co, Mn, Cr, V, Al, Fe, B, Si, Mg and Zn, 0.5???1, ?0.1???0.1, 0<a<0.95, 0<b<0.25, 0<c<0.3, 0<d<0.6, a+b+c+d=1, and the charge neutrality condition is met. Also provided in the present invention is a preparation method for and the use of the multi-element co-doped sodium-ion positive electrode material.

Abstract: A respiratory ventilation apparatus configured to deliver a respiratory gas to a patient interface is provided. The apparatus may include a gas pressurization unit configured to generate a pressurized respiratory gas, a gas inlet port configured to introduce the respiratory gas into the respiratory ventilation apparatus, a gas outlet port configured to discharge the pressurized respiratory gas to a respiration tube, a detection module configured to detect the pressure of the pressurized respiratory gas, at least one non-volatile memory configured to store a plurality of parameters and a plurality of programs, and one or more controllers. The one or more controllers may be configured to initiate the respiratory ventilation apparatus upon a boot operation, and/or initiate a program that constantly reads information from the detection module, and controls the pressure of the pressurized respiratory gas using the information read from the detection module and at least one parameter.