Abstract: A dual-direction synchronous loading method for a true-triaxial test apparatus includes the following steps: Step S1, loading a sample and adjusting the sample at a center of a sample box and a rigid loading frame; Step S2, setting parameters and sending action instructions through a computer control panel; and Step S3, collecting load signals collected by each sensor acquired by a PID controller, and coordinating a size of triaxial dual-direction loading loads to realize a single instruction dual-direction synchronous loading. The method ensures that a rock sample is kept at a center of a pressure chamber before being loaded, so that a focus of a loading axis is always at a same position as a center of the sample in space, and the function of synchronous loading of two loading actuators in the same direction under a single instruction can be achieved.

Abstract: A monolithic integrated multi-segment cascade optical frequency comb and its chip are disclosed, which belongs to the technical field of sensing detection, quantum information and optical communication technology. The optical frequency comb includes a first semiconductor passive mode-locking laser, a semiconductor optical amplifier, and a second semiconductor passive mode-locking laser sequentially integrated and connected; the first semiconductor passive mode-locking laser includes a first reverse bias absorption area integrated with an optogalvanic distribution grating and a first gain cavity length extender (coupled multi-ring or multi-disk); the second semiconductor passive mode-locking laser includes a second reverse bias absorption area and a second gain cavity length extender (coupled multi-ring or multi-disk); each structure is connected to each other by electrical isolation grooves.

Abstract: Disclosed are solid forms of an activator of soluble guanylate cyclase (sGC). The invention also relates to methods of making these solid forms, pharmaceutical compositions comprising these solid forms, and their use for medical conditions responsive to treatment with an activator of sGC.

Abstract: Disclosed are a phenyl amino sodium propionate derivative, a preparation method therefor and an application thereof. Specifically, disclosed are sodium 3-(4-(2-(9H-carbazole-9-yl)ethoxy)phenyl)-2-((2-(4-(4-(2-sodium forrnate-2-((2-(4-fluorobenzoyl)phenyl)amino)ethyl)phenoxy)benzoyl)phenyl)amino)propionate, a preparation method therefor and the use thereof for quality control of a bulk drug or formulation of Chiglitazar or a derivative thereof. Particularly, the compound can be used as a control substance or standard substance for the detection of impurities/related substances in Chiglitazar or a sodium salt drug thereof.

Abstract: The present invention disclosure also relates to a pharmaceutical composition that ccomprises the compound as an active ingredient.

Abstract: The present invention relates to a hydroxamate compound represented by formula (I), a preparation method therefor, and an application thereof. The present invention also relates to a pharmaceutical composition comprising the compound as an active ingredient and a use of the compound or pharmaceutical composition for treating and/or preventing related diseases mediated by TYK2.

Abstract: A biphenyl compound represented by formula (I), a preparation method therefor and an application thereof. The present invention also relates to a pharmaceutical composition that comprises the compound as an active ingredient. The compound is a novel small molecule immunomodulator having excellent oral absorption features and can be used for treating and/or preventing various immunity-related diseases.

Abstract: A biphenyl compound represented by formula (I), a preparation method therefor and an application thereof. The present invention also relates to a pharmaceutical composition that comprises the compound as an active ingredient. The compound is a novel small molecule immunomodulator having excellent oral absorption features and can be used for treating and/or preventing various immunity-related diseases.

Abstract: The disclosure relates to the technical field of battery charging and swapping, and in particular, to a control method and system for a battery charging and swap station, a medium, an apparatus, and a battery charging and swap station. The disclosure is intended to solve the problem that a battery charging and swap station is prone to false alarm and halt at a low temperature. To this purpose, the battery charging and swap station in the disclosure includes a battery swap apparatus. The battery swap apparatus includes a locking/unlocking mechanism. The locking/unlocking mechanism is configured to be capable of locking and unlocking a battery locking mechanism through rotation of a locking/unlocking head of the locking/unlocking mechanism.

Abstract: A peridynamics-based finite element method (PeriFEM) for an structural damage analysis, comprising the following steps: A1: generating finite elements of a structure, A2: generating peridynamic elements based on the finite elements; A3: calculating a global load vector; A4: calculating a global stiffness matrix; A5: formulating and solving a linear algebra equation about the global node displacement vector; A6: evaluating whether the result satisfies the convergence criteria; if so, go to step A7, if not, return to step A4; A7: increasing the external load successively and loop A3-A7 after that, until the external load exceeds the maximum external load; A8: plotting the results. The implementation of PeriFEM in software includes the following operations: B1: generating the peridynamic elements for inputting into the software; B2: programing the formulation of the element stiffness matrix in step A4 as a subroutine; and B3: setting a method for the updating the subroutine.

Abstract: The disclosure relates to the technical field of safety protection, and in particular, to a safety protection method and system for a battery charging and swap station, a medium, an apparatus, and the battery charging and swap station. The disclosure aims to solve the problem of small coverage of an existing safety protection method. For this purpose, the battery charging and swap station in the disclosure includes a battery swap platform, a battery swap apparatus, position detection devices, and safety scanning devices. The battery swap platform can bear a vehicle with a battery to be swapped. The position detection devices can send an electrical signal when blocked. The safety scanning devices can monitor one of a plurality of preset monitoring regions each time.

Abstract: The present disclosure discloses a method and a system for automatically resuming a call after network handover, and belongs to the field of network calls. In the method of the present disclosure, during a call between a first terminal and a second terminal, when the first terminal is handed over from a first network to a third network, the first terminal first stores call resources, then registers with a server through the third network, constructs a resume request, and sends the resume request to the second terminal via the server, and the second terminal resumes the call with the first terminal according to the resume request. The present disclosure can ensure communication stability after network handover of a communication device, thereby avoiding call interruption caused by the network handover during communication of the communication device.

Abstract: In the present disclosure, a piece is disposed on a glove core of a glove structure, and an edge of the piece is to injected and filled with molding material to have an injection molding assembly thereon. The injection molding assembly at least fills a section gap between the glove core and the edge of the piece. By using the injection molding assembly, the section gap between the glove core and the edge of the piece is masked, and an adhesive effect for bonding the piece is also obtained. Thus, the present disclosure provides positive and reliable means for preventing the edge of the piece from being separated from the glove core, making the glove structure maintain its required function in long term, increasing the quality and the lifetime of the glove structure, and making the glove structure have a curved surface shape to present its three-dimensional shape.

Abstract: A mask, a mask assembly, an exposure machine, a method for testing shadowing effect on a window, and a photolithography method are provided. The mask includes a light transmission area; a functional window provided at a side of the light transmission area; and at least one of a first detection mark and a second detection mark; wherein the first detection mark is flushed with a border of the functional window adjacent to an interior of the mask; and the second detection mark is disposed between the profile of the light transmission area and the functional window.

Abstract: Provided is a quinoline derivative having indoleamine-2,3-dioxygenase inhibitory activity, specifically, provided is a compound of general Formula (I) or pharmaceutically acceptable salt thereof, its pharmaceutical composition, preparation method and use in the manufacture of a medicament for immunomodulating and preventing and/or treating of a disease associated with IDO expression abnormality and/or tryptophan metabolism abnormality. Also provided is use of a combination medication of the quinoline derivative and HDAC inhibitor and its use in the manufacture of an anti-tumor drug.

Abstract: A mask, a mask assembly, an exposure machine, a method for testing shadowing effect on a window, and a photolithography method are provided. The mask includes a light transmission area; a functional window provided at a side of the light transmission area; and at least one of a first detection mark and a second detection mark; wherein the first detection mark is flushed with a border of the functional window adjacent to an interior of the mask; and the second detection mark is disposed between the profile of the light transmission area and the functional window.

Abstract: A glove has a glove core and a glove component. The glove core has a palm portion, a dorsum portion, a side portion of hand and a finger portion; the palm portion and the finger portion are connected to each other via a connection point, the finger piece portion has a first and second bonding portions with a distance therebetween, the finger piece portion is bound to the finger portion via the first bonding portion, and the finger piece portion is bound to the palm portion via the second bonding portion. The connection point, the first bonding portion and the second bonding portion are formed to have a virtual triangle, thus the finger portion and the palm portion have an angle being less than 180 degrees, and that is, the finger portion bends forward the palm portion to make the glove comply with the ergonomic principle.

Abstract: The present invention relates to a formamide compound, a preparation method therefor and an application thereof. The structure of the compound is shown in formula (I), and the definition of each variable in the formula is as provided in the description. The compound is capable of inhibiting the activity of ASK1 kinase. The compound of the present invention may be used in the treatment/prevention of diseases associated with ASK1 kinase, such as inflammatory diseases, metabolic diseases, autoimmune diseases, cardiovascular diseases, neurodegenerative diseases, cancers and other diseases.

Abstract: A glove structure of the present invention has a glove palm, a glove back and an edging. The edging is a bent sheet and has an upper side edge and a lower side edge, wherein the lower and upper side edges are respectively adhered to the glove palm and the glove back via joining regions, and the lower and upper side edges bend toward the glove palm. Thus, the whole glove structure bends along a direction being from the glove back to the glove back to make the glove structure be a ergonomics structure which the fingers bend toward the glove palm when the human hand is under a working state or a general state without force.