Patents by Inventor Zhibin Luo

Zhibin Luo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Naphthylurea derivatives and medical applications thereof
    Patent number: 9469639
    Abstract: The present invention relates to naphthylurea derivatives. Such substances can significantly inhibit VEGFR2 and PDGFR-? receptor tyrosine kinase phosphorylation at nanomolar concentration levels. It is a novel type of tyrosine kinase inhibitors which can be used in the treatment of tyrosine kinase-mediated diseases or symptoms such as malignancies and ocular diseases accompanied with pathologic neovascularization.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: October 18, 2016
    Assignee: Radiant Pharma & Tech. Co., Ltd.
    Inventors: Yingjian Hu, Zhibin Luo, Yanhong Zhang, Li Han, Yun Wang, Hongfei Lu
  • NAPHTHYLUREA DERIVATIVES AND MEDICAL APPLICATIONS THEREOF
    Publication number: 20160207916
    Abstract: The present invention relates to naphthylurea derivatives. Such substances can significantly inhibit VEGFR2 and PDGFR-? receptor tyrosine kinase phosphorylation at nanomolar concentration levels.
    Type: Application
    Filed: August 20, 2014
    Publication date: July 21, 2016
    Inventors: Yingjian HU, Zhibin LUO, Yanhong ZHANG, Li HAN, Yun WANG, Hongfei LU
  • Chiral catalyst, process for preparing the same and its use in the oxidate coupling of naphthols
    Patent number: 7151070
    Abstract: The compound of this invention is a useful catalyst for the oxidative coupling of naphthol. Its originality lies in that it is a novel vanadium complex of Schiff's base formed by a chiral amino acid and a formyl biphenol or its derivative. Its axis chirality is induced to form by the chiral amino acid. It has the general formula: where R represents a benzyl, an isopropyl, an isobutyl or a tertiary butyl and the configuration of the amino acid is R or S. The compound can catalyze oxidative coupling of naphthol or its derivative to form binaphthol or its derivatives with a high optical purity.
    Type: Grant
    Filed: February 27, 2003
    Date of Patent: December 19, 2006
    Assignee: Chengdu Institute of Organic Chemistry Chinese Academy of Sciences
    Inventors: Liuzhu Gong, Zhibin Luo, Quanzhong Liu, Aiqiao Mi, Yaozhong Jiang
  • Chiral catalyst, process for preparing the same and its use in the oxidate coupling of naphthols
    Publication number: 20050256345
    Abstract: The compound of this invention is a useful catalyst for the oxidative coupling of naphthol. Its originality lies in that it is a novel vanadium complex of Schiff's base formed by a chiral amino acid and a formyl biphenol or its derivative. Its axis chirality is induced to form by the chiral amino acid. It has the general formula: where R represents a benzyl, an isopropyl, an isobutyl or a tertiary butyl and the configuration of the amino acid is R or S. The compound can catalyze oxidative coupling of naphthol or its derivative to form binaphthol or its derivatives with a high optical purity.
    Type: Application
    Filed: February 27, 2003
    Publication date: November 17, 2005
    Applicant: Chengdu Institute of Organic Chemistry Chinese Academy of Sciences
    Inventors: Liuzhu Gong, Zhibin Luo, Quanzhong Liu, Aiqiao Mi, Yaozhong Jiang